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This paper presents the development as well as the architecture of a computer-aided dedicated fixture design system intended to support the design of lightweight (carbon fiber composite) grippers for a major truck company. Lightweight grippers were required due to the increasing production rates in the automotive industry. The current robotic equipment was facing diverse problems during transporta
The United Nations (UN)-led global consultations on new development goals, which will replace the Millennium Development Goals (MDGs), started in 2012. In comparison with the creation of the MDGs, the road towards the post-2015 goals is much more inclusive and participatory. The consultations are part of a longer trend, in which intergovernmental organizations seek to strengthen their legitimacy
The paper provides an attempt to direct the research in the area of venture capitalist and the board of directors in SMEs. Issues about boards in venture capital-backed technology based industrials are explored, and various research designs are used to meet different research questions. Empirical results indicate that venture capital firms purposefully use boards in the portfolio firm, and boards
Particle size distributions and hygroscopic growth were studied in a town in Sweden with extensive emissions from wood combustion. The average deposited fraction of particle number, surface area and volume dose in the human respiratory tract was estimated using the data set, as well as the typical deposition pattern of the two dominant particle source types: wood combustion and traffic exhaust. As
OBJECTIVE: To define a minimum Standard Set of outcome measures and case-mix factors for monitoring, comparing, and improving healthcare for patients with clinically diagnosed hip or knee osteoarthritis (OA) with a focus on defining the outcomes that matter most to patients. METHODS: An international Working Group (WG) of patients, arthroplasty register experts, orthopedic surgeons, primary care
The ability of particles to activate and form cloud droplets influences the functioning of the Earth's hydrological cycle. This work links the particle water uptake at subsaturation to the critical supersaturation ratio needed for particles to become cloud condensation nuclei (CCN). Five models using the particle hygroscopic growth at subsaturation for predicting the critical supersaturation neede
The dynamic regulation of ligand binding is considered crucial for integrin function. However, the importance of activity regulation for integrin function in vivo is largely unknown. Here, we have applied gene targeting to delete the GFFKR sequence of the lymphocyte function-associated antigen-1 (LFA-1) alpha(L) subunit cytoplasmic domain in mouse germline. Lymphocytes from Lfa-1(d/d) mutant mice
In this paper, multiple windows, optimal for locally stationary processes (MW-LSP) are used to estimate the spectrogram of the electroencephalogram (EEG) where we focus on the ability to estimate transient frequency changes. A peak of known frequency was evoked in the EEG spectrum in a predetermined time interval, by using a 9 Hz flickering light. We investigate the multiple windows corresponding
Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide with anti-tumor activity. Here we show that when bound to anginex, galectin-1 binds various glycoprotei
This is a thesis about interdisciplinarity, scientific integration, and problem solving in sustainability science. Sustainability science is an emerging and highly interdisciplinary field that seeks to integrate vastly differentiated bodies of knowledge in addressing the challenge of transitioning contemporary societies towards sustainability. Interdisciplinarity is paramount. Interdisciplinarity
A search for resonant and nonresonant pair production of Higgs bosons in the bbτ+τ- final state is presented. The search uses 36.1 fb-1 of pp collision data with s=13 TeV recorded by the ATLAS experiment at the LHC in 2015 and 2016. Decays of the τ-lepton pairs with at least one τ lepton decaying to final states with hadrons and a neutrino are considered. No significant excess above the expected b
Climate change increases the risks of heat stress, especially in urban areas where urban heat islands can develop. This literature review aims to describe how severe heat can occur and be identified in urban indoor environments, and what actions can be taken on the local scale. There is a connection between the outdoor and the indoor climate in buildings without air conditioning, but the pathways
The personal union between Norway and Sweden, established in 1319, has received little interest by historians, and is usually seen as terminated in 1363, if not earlier. But it was, in fact, an important factor in Scandinavian politics all the way until the establishment of the Kalmar Union under Queen Margrete in 1389. Important parts of western Sweden stayed in the union with Norway, which gave
Background Depression is a common disorder in both men and women, and the recurrence rate is high. The aim of this study was to identify risk factors for recurrence in depression in the Lundby Study. Methods The Lundby Study is a community-based longitudinal study with focus on mental health. The study started in 1947 and three follow-ups have been carried out since, the last one in 1997. The po
