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Apoptotic cells have been reported to down- regulate membrane-bound complement regulatory proteins ( m- C- Reg) and to activate complement. Nonetheless, most apoptotic cells do not undergo complement- mediated lysis. Therefore, we hypothesized that fluid phase complement inhibitors would bind to apoptotic cells and compensate functionally for the loss of m- C- Reg. We observed that m- C- Reg are d

The solid state structure of endo,endo-bicyclo[3.3.1]nonane-2,6-diol, rac-2, shows a hydrogen bonded, three-connected, chiral 3D-net with utg-topology, distinctively different from those formed by the so called tubuland diols, e.g. 2,6-dimethylbicyclo[3.3.1]nonane-exo2, exo-6-diol, rac-5, that crystallise as three-connected, chiral etanets and from the qtz-net formed by weaker hydrogen bonds in th

Protein affinity reagents (PARs), most commonly antibodies, are essential reagents for protein characterization in basic research, biotechnology, and diagnostics as well as the fastest growing class of therapeutics. Large numbers of PARs are available commercially; however, their quality is often uncertain. In addition, currently available PARs cover only a fraction of the human proteome, and thei

BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015.METHODS: We estim

Planets form in protoplanetary discs of gas, dust and ice around newborn stars. In the Solar System, not only planets are found as a result from the time of planet formation, but also remnant planetesimals in the form of asteroids, Kuiper belt objects and comets. Recent observations, e.g. by the space mission Rosetta, have found that comets are porous objects barely able to hold themselves togethe

En sammanfattning av uppsatsen på maximalt 8000 tecken. This thesis is mainly dealing with the mobility of the employees within the borders of the European Union. Legislative framework from the EU is favourable and the Commission has set as one of it goals to promote the migration. Globalisation trends and contemporary business concepts need people who are mobile on the other hand. But migration n

Context The relationship of platelet function testing measurements with outcomes in patients with acute coronary syndromes (ACS) initially managed medically without revascularization is unknown. Objective To characterize the differences and evaluate clinical outcomes associated with platelet reactivity among patients with ACS treated with clopidogrel or prasugrel. Design, Setting, and Patients Pat

Southeast Asia is the hardest-hit region worldwide regarding the frequency and severity of natural hazards, which are deemed to increase significantly in the incoming years. The International Red Cross and Red Crescent Movement (RCRC) in Southeast Asia, through its International Federation of Red Cross and Red Crescent Societies (IFRC) Asia Pacific Regional Office (RO), IFRC Country Cluster Suppor

Water for firefighting is often associated with drinking water, due to fire hydrants. Fire hydrants have been installed in towns for a long time and are one of the most common ways for the rescue service to get hold of water for extinguishing fires. This report evaluates the ways that the rescue service uses their water and how the get continuously water to the fire site. Other extinguishing metho

Gendered violence against woman and children has been in existence and predominant in various societies for a long period of time with its intensity varying from one factor to the other. Many nations around the world including Ghana in West Africa have measures and directives to mitigate of the persistent social menace and possibly eradicate it towards sustainable welfare and development for indiv

In later time many companies have faced a major strategically change of focus and companies that have previous acted as traditional product manufacturers now describe themselves as providers of complete solutions. Tetra Pak Processing Systems, operating in the liquid food processing industry, has faced an increased level of competition the past years. The globalization of the industry means that c

OBJECTIVE: To compare costs of transurethral prostatic resection (TURP) and transurethral microwave thermotherapy (TUMT) for symptomatic benign prostatic hyperplasia (BPH) in a randomized, controlled trial. METHODS: In 70 BPH patients all costs were calculated for management, including complications and repeat treatment, during TURP or TUMT and 24-month follow-up. Clinical outcome was judged from

This article presents new evidence on the efforts of states to collect and process information about themselves, their territories, and their populations. We compile data on five institutions and policies: the regular implementation of a reliable census, the regular release of statistical yearbooks, the introduction of civil and population registers, and the establishment of a government agency ta

Relying on three new indicators of the information capacity of states, this paper provides new evidence on the ability of states to collect and process information about the territories and populations that they govern. The three indicators are (a) the availability of a reliable census, (b) the establishment of a permanent government agency tasked with processing statistical information about the