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Al-Ga-based alloys are promising carriers of renewable energy, which can provide hydrogen by hydrolysis in challenging working environments. Manipulating their performance by different process conditions and comprehending the mechanisms are important for achieving directional design synthesis of alloys and enhancing their practicality. This study presents a novel approach to optimizing the hydroge
Dator- och TV-spel är relativt nyligen introducerade och komplext utformade verk, vilket innebär en utmaning avseende upphovsrättsligt skydd. I huvudsak består ett sådant spel av ett flertal olika upphovsrättsliga alster, inkluderande programvaran, som är oupplösligt sammansatta i en och samma produkt. Detta leder till att den upphovsrättsliga klassificeringen varierar beroende på aktuell jurisdikThe video game poses a challenge in terms of copyright protection due to the complexity and novelty of its nature, in essence being comprised of multiple copyrightable elements, resulting in jurisdictionally diverse legal classification and harmonisation within the EU is not yet achieved. As the varying options of copyright classification of video game affects the applicability of EU anti-circumve
Ice covers ten percent of the earth’s surface, seven percent of its oceans and is currently dominating the visual landscape as a key theme of climate communication in the media. Focusing on representations of climate change that implement ice as a key motif, this thesis postulates why and how climate discourse shapes, and is shaped by, the technological, social and institutional production of imag
Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are recognized as severe diseases of the lungs and are closely linked to cigarette smoking and environmental pollution and share common mechanisms such as oxidative stress, inflammation, matrix degradation, and airway remodeling. Epidermal growth factor receptor (EGFR), a transmembrane receptor featuring an extracellular ligand bind
Non-native plants are a growing problem in Antarctica. By encroaching on native plants’ habitats, they risk leaving the last frontier of authentic wilderness irreversibly altered. As the climate continues to change and more people visit Antarctica, non-native plants’ spread and impacts are expected to become more severe. The Protocol on Environmental Protection to the Antarctic Treaty prohibits in
AimOur aim is to provide a-priori information on air-quality implications of potential future energy carriers in transportation relevant for sustainability, life cycle and health-impact assessments.MethodologyInformation on air- and climate-pollutant formation from energy carriers is collected in detailed laboratory assessments on heavy-duty combustion engines as well as on non-tailpipe emissions.
This project was based on a thesis about how product semiotics and aesthetics has defined a design standard for many products. Hence the development for those products may have stagnated. The proj- ect began by researching different products and domains to see how designers throughout the years had “thought outside the box”, to then try to see how much I could push towards that direction. The fi
In a digital age where travellers are increasingly looking for the cheapest, fastest or most sustainable way to travel, comparing different modes of transport efficiently becomes a challenge. The internet offers a wide range of websites and travel providers, fragmenting information and forcing travellers to navigate inefficiently between different platforms and websites. Multimodal Digital Mobili
Designing high-rise buildings is a complex and challenging task involving several parameters and variables. Recently, there have been major attempts to design the overall form of these buildings based on optimization approaches. This paper introduces a multi-objective optimization framework based on Genetic Algorithm, namely Energy Efficient Form-finder (EEF), consisting of four main steps of Form
The (p)ppGpp-mediated stringent response is a bacterial stress response implicated in virulence and antibiotic tolerance. Both synthesis and degradation of the (p)ppGpp alarmone nucleotide are mediated by RelA-SpoT Homolog (RSH) enzymes which can be broadly divided in two classes: single-domain ‘short’ and multi-domain ‘long’ RSH. The regulatory ACT (Aspartokinase, Chorismate mutase and TyrA)/RRM
Energy security has become a key priority in the European Union’s (EU) policy. However, climate change mitigation commitments run in parallel. The purpose of this paper is to analyze the extent to which the EU’s climate change mitigation and energy security policies are coherent. The relationship is far from clear-cut, as both areas are complex and wide-ranging. We use a simple assessment framewor
This study examines the management of used mobile phones in the United Kingdom between 2005 and 2008. It shows that the replacement cycle for mobile phones got shorter during the period due to heavy handset subsidies given by mobile network operators. The planned obsolescence presented a business opportunity for the exports of used phones to developing countries. However, the collection for re-use
The plasminogen activator (PA) system has been proposed to have important roles in rheumatoid arthritis. Here we have used the autoinumme collagen type II (CII)-induced arthritis (CIA) model and mice deficient for urokinase-type PA (uPA) or plasminogen to investigate the role of the PA system for development of arthritis. Our data revealed that uPA-deficient mice have a lower severity and incidenc
AIMS/HYPOTHESIS: The molecular mechanisms of insulin release are only partially known. Among putative factors for coupling glucose metabolism to insulin secretion, anaplerosis has lately received strong support. The anaplerotic enzyme pyruvate carboxylase is highly expressed in beta cells, and anaplerosis influences insulin secretion in beta cells. By inhibiting pyruvate carboxylase in rat islets,
The cAMP response element-binding protein (CREB) is believed to play a pivotal role in dopamine (DA) receptor-mediated nuclear signaling and neuroplasticity. Here we demonstrate that the significance of CREB for gene expression depends on the experimental paradigm. We compared the role of CREB in two different but related models: L-DOPA administration to unilaterally 6-hydroxydopamine lesioned rat
