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Chronic respiratory diseases, such as asthma, represent a significant global health issue. Symptoms are commonly treated through inhalation therapy, enabling the delivery of the active pharmaceutical ingredient (API) directly to the lungs. Pulmonary drug delivery offers several advantages, including reduced risk of systemic side effects and a minimally invasive route of administration. Dry-powder
Till följd av digitaliseringen har annonsmarknaden genomgått en strukturell förändring där sociala medier har blivit en framträdande marknadsföringskanal. Samtidigt använder nästan samtliga barn i Sverige sociala medier i dag. Inom marknadsföringsrätten anses barn utgöra särskilt sårbara konsumenter, vilket föranlett att barn erhåller ett särskilt marknadsföringsrättsligt skydd. Den senaste tiden Due to digitalization, the advertising market has undergone a structural shift, with social media emerging as a prevalent marketing channel. Simultaneously, almost all children in Sweden use social media today. Within marketing law, children are considered particularly vulnerable consumers and as a result children are afforded additional legislative protection. Nevertheless, shortcomings in the ad
In paediatric hospital wards, parents or caregivers who are physically capable are already present with their child when a fire emergency occurs. Yet existing approaches to hospital evacuation have either overlooked their potential role or treated them as additional occupants for staff to manage. If these caregivers could evacuate independently with their child, staff could direct their efforts to
This paper investigates the characteristics and history of value added taxes. Many previous studies have focused on the theoretical implications of value added taxes; this paper differs in the method used as well as the phrasing of research question. This paper seeks out to answer whether a redesign of the current Value Added Tax system in Sweden could be a Pareto improvement. It looks at relevant
The paper researches the viable options for Hamas as a case study in the development of a peace paradigm through answering the question of ‘What should Hamas do, while under siege, to act responsibly in favor of the interests of its constituency?’ By comparing the logics of social constructivist and realist theories as methods of analysis in addressing the formulation, operationalization and socia
Rapid Diagnostic Tests (RDTs) for malaria are restricted to a few biomarkers and antibody-mediated detection. However, the expression of commonly used biomarkers varies geographically and the sensibility of immunodetection can be affected by batch-to-batch differences or limited thermal stability. In this study we aimed to overcome these limitations by identifying a potential biomarker and by deve
Marine sedimentary ikaite is the parent mineral to glendonite, stellate pseudomorphs found throughout the geological record which are most usually composed of calcite. Ikaite is known to be metastable at earth surface temperatures and pressures, readily breaking down to more stable carbonate polymorphs when exposed to warm (ambient) conditions. Yet the process of transformation of ikaite to calcit
In this chapter we summarize the solution developed by team KTH for the Amazon Picking Challenge 2016 in Leipzig, Germany. The competition, which simulated a warehouse automation scenario, was divided into two parts: a picking task, where the robot picks items from a shelf and places them into a tote, and a stowing task, where the robot picks items from a tote and places them in a shelf. We descri
The Cherenkov Telescope Array (CTA) is the next-generation gamma-ray observatory currently under construction. It will improve over the current generation of imaging atmospheric Cherenkov telescopes (IACTs) by a factor of five to ten in sensitivity and it will be able to observe the whole sky from a combination of two sites: a northern site in La Palma, Spain, and a southern one in Paranal, Chile.
Using molecular simulation to aid in the analysis of neutron reflectometry measurements is commonplace. However, reflectometry is a tool to probe large-scale structures, and therefore the use of all-atom simulation may be irrelevant. This work presents the first direct comparison between the reflectometry profiles obtained from different all-atom and coarse-grained molecular dynamics simulations.
Background: Small-angle scattering (SAS) is a powerful technique capable of determining the sample averaged structure of systems within sizes ranging from 1 nm to ~500 nm. This is particularly useful when applied to the study of self-assembled organic systems. Objective: This review article introduces the method of model-dependent analysis of small angle scattering. Method: The underlying mathemat
Differential equations are an important building block for modeling processes in physics, biology, and social sciences. Usually, their exact solution is not known explicitly though. Therefore, numerical schemes to approximate the solution are of great importance. In this thesis, we consider the temporal approximation of nonlinear, nonautonomous evolution equations on a finite time horizon. We pres
INTRODUCTION: Recent clinical trials of amyloid beta (Aβ)-targeting therapies in Alzheimer's disease (AD) have demonstrated a clinical benefit over 18 months, but their long-term impact on disease trajectory is not yet understood. We propose a framework for evaluating realistic long-term scenarios. METHODS: Results from recent phase 3 trials of Aβ-targeting antibodies were integrated with an estim
The costly and complex needs for children with long-term illness are challenging. Safe eHealth communication is warranted to facilitate health improvement and care services. This mixed-methods study aimed to describe parents’ usage and experiences of communicating with professionals during hospital-to-home-transition after their child’s preterm birth or surgery for col-orectal malformations, using
Emerging data indicates SGRT could improve safety and quality by preventing errors in its capacity as an independent system in the treatment room. The aim of this work is to investigate the utility of SGRT in the context of safety and quality. Three incident learning systems (ILS) were reviewed to categorize and quantify errors that could have been prevented with SGRT: SAFRON (International Atomic
In order to reduce maritime transportation's greenhouse gas and pollutant emissions, marine engine manufacturers need to deepen the fundamental understanding of the injection and spray process. Two-dimensional unsteady-state Reynolds-averaged Navier-Stokes simulations were conducted to investigate evaporating high-pressure marine engine sprays, in which an injector with a nozzle diameter of 0.44 m
Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of disease and no available disease-modifying treatments. Symptomatic early-stage OA of the knee (the focus of this Review) urgently needs to be identified and defined, as efficient early-stage case finding and diagnosis in primary care would enable health-care providers to proactively and substantially reduce
We approach critically the assertion that a referendum ultimately defends the “traditional family,” by examining the articulation of anti-gender politics in Romanian parliamentary debates. We contribute theoretically by employing the concept of retrogressive mobilization in plebiscitary circumstances. We show that in Romania the contours of retrogressive mobilization transgress both the ideologica
