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Cytokines play an important role in the regulation of homeostasis and inflammation. A de-regulated cytokine function can subsequently promote chronic inflammation. This is supported by clinical evidence showing the beneficial effect of inhibiting TNF-alpha through injection of antibodies and soluble receptor in disorders such as rheumatoid arthritis and Crohn's disease. Systemic anti-TNF-alpha the
This work aims to evaluate the predictive strength of the relative seriality, parallel and Lyman-Kutcher-Burman (LKB) normal tissue complication probability (NTCP) models regarding the incidence of radiation pneumonitis (RP), in a group of patients following lung cancer radiotherapy and also to examine their correlation with pulmonary function tests (PFTs). The study was based on 47 patients who r
Mechanically strong and flexible membranes with very high local concentrations of immobilized proton-conducting phosphonic acid have been achieved by grafting poly(vinylphosphonic acid) side chains onto polysulfones. The graft copolymers were prepared by anionic polymerization of diethyl vinylphosphonate initiated from lithiated polysulfones, followed by quantitative cleavage of the ester function
Background and Purpose: The purpose of this study was to determine which leads in the standard 12-lead electrocardiogram (ECG) are the best for detecting acute coronary syndrome (ACS) among chest pain patients in the emergency department. Methods: Neural network classifiers were used to determine the predictive capability of individual leads and combinations of leads from 862 ECCs from chest pain
Kursguide - Course Syllabus • • • • Fastställande Kursplanen är fastställd av Ledningsgruppen för kandidatprogrammet i Food Service Management och Logistics Service Management 2012-05-21 och senast reviderad 2012-09-11. Den reviderade kursplanen gäller från och med 2012-10-01, vårterminen 2013. Allmänna uppgifter Kursen är en obligatorisk kurs inom kandidatprogrammet för Logistics Service Manageme
https://www.ses.lu.se/sites/ses.lu.se/files/kp_smlb203.pdf - 2026-06-25
The Coastal Giant Salamander (Dicamptodon tenebrosus) is classified as threatened at the northern periphery of its range in British Columbia (BC), Canada, primarily due to forestry practices and habitat fragmentation. Characterising dispersal behaviour and population connectivity is therefore a priority for this region, while genetic differentiation in core versus peripheral locations remains unst
Coprolites (fossilized faeces) are common, yet previously unreported, elements in the Campanian (Upper Cretaceous) shallow-marine strata of Asen, southern Sweden. They are associated with a diverse vertebrate fauna and comprise at least seven different morphotypes that suggest a variety of source animals. Their faecal origin is corroborated by several lines of evidence, including chemical composit
This study examined mortality and predictors of death in 1,396 primary amphetamine users (85% males) who were interviewed with the Addiction Severity Index in the Swedish criminal justice system during 2000-2006 and followed through 2008. Forty-nine clients deceased (standardized mortality ratio 4.1 [3.0-5.4]), at least 84% of deaths were violent or drug-related (12% suicides), and Cox regression
Purpose: To what extent active surveillance and deferred treatment for localized risk prostate cancer are used is unclear. We assessed the use of surveillance and of deferred treatment in a population based, nationwide cohort in Sweden. Materials and Methods: In the National Prostate Cancer Register of Sweden, with a 98% coverage vs the compulsory Swedish Cancer Registry, we identified 8,304 incid
The European Spallation Source (ESS) linac will consist of three families of superconducting RE cavities to accelerate protons to a final beam energy of 2.5 GeV for collision with the target. Beam induced HOMs in these cavities may drive the beam unstable and increase the cryogenic load, severely limiting the operation of the linac. The effect of these modes on the beam quality is investigated in
Moving towards circular economy is considered as a fundamental way to achieve sustainable development, but practices and tools that can support businesses in implementing this concept are still underdeveloped. Moreover, there is uncertainty about the impact that the adoption of circularity has on the current way of working of a company. With the adoption of aspects of action research on a rock and
Electricity price prediction is increasingly important as the prices become more volatile due to the expan- sion of weather-dependent renewable electricity sources. The electricity market of focus in this thesis is the Nord pool intraday market and the regulating prices occurring on it. For actors trading on the intra- day market increased volatility implies greater risks since the regulating pric
The relevance of M&E insights being utilized for reporting, contra planning purposes, for predicting level of outcome implementation have been neglected in previous literature. However, this study can show that when measurements and evaluations is used for future planning of communication activities, level of outcome implementation increase largely. This study can also predict the level of wh
The type of pattern recognition methods used for controlling modern prosthetics, referred to here as single-label classification methods, restricts users to a small amount of movements. One prominent reason for this is that the accuracy of these classification methods decreases as the number of allowed movements is increased. In this work a possible solution to this problem is presented by looking
The purpose of this study was to investigate whether Södra Cell Mörrum, SCM, could invest in a steam turbine to produce profitable electricity from excess steam, which is currently being released into the atmosphere. Furthermore, this study investigated the potential side effects from this installation and suggests solutions. This study was conducted in two phases: collecting data which was then s
This Letter presents evidence for the associated production of a W boson and a top quark using 2.05 fb(-1) of pp collision data at root s = 7 TeV accumulated with the ATLAS detector at the LHC. The analysis is based on the selection of the dileptonic final states with events featuring two isolated leptons, electron or muon, with significant transverse missing momentum and at least one jet. An appr
Users of Business Intelligence (BI) systems have started to demand more flexible systems in which they could be empowered to serve themselves – self-service BI. In this paper we aim at explaining how such development influences designers of BI solutions and how it impacts the design situation. To say something about this we adapted the PACT (People, Activity, Context, Technology) framework on the
A search is reported for Higgs boson decay to mu(+)mu(-) using data with an integrated luminosity of 24.8 fb(-1) collected with the ATLAS detector in pp collisions at root s = 7 and 8 TeV at the CERN Large Hadron Collider. The observed dimuon invariant mass distribution is consistent with the Standard Model background-only hypothesis in the 120-150 GeV search range. For a Higgs boson with a mass o
A capillary-based model modified for characterization of monolithic cryogels is presented with key parameters like the pore size distribution, the tortuosity and the skeleton thickness employed for describing the porous structure characteristics of a cryogel matrix. Laminar flow, liquid dispersion and mass transfer in each capillary are considered and the model is solved numerically by the finite
