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The type III receptor tyrosine kinase FLT3 is frequently mutated in acute myeloid leukemia. Oncogenic FLT3 mutants display constitutive activity leading to aberrant cell proliferation and survival. Phosphorylation on several critical tyrosine residues is known to be essential for FLT3 signaling. Among these tyrosine residues, Y842 is located in the so-called activation loop. The position of this t
Smooth muscle cell (SMC) proliferation is a key process in stabilization of atherosclerotic plaques, and during restenosis after interventions. A clearer understanding of SMC growth regulation is therefore needed to design specific anti-proliferative therapies. Retinoic acid has been shown to inhibit proliferation of SMCs both in vitro and in vivo and to affect the expression of extracellular matr
We investigated the function of cyclin-dependent kinase 2 (Cdk2) in neural progenitor cells during postnatal development. Chondroitin sulfate proteoglycan (NG2)-expressing progenitor cells of the subventricular zone (SVZ) show no significant difference in density and proliferation between Cdk2-/- and wild-type mice at perinatal ages and are reduced only in adult Cdk2 -/- mice. Adult Cdk2-/- SVZ ce
The first positive genome-wide association study on gestational length and preterm delivery showed associations with a gene involved in the selenium metabolism. In this study we examine the associations between maternal intake of selenium and selenium status with gestational length and preterm delivery in 72,025 women with singleton live births from the population based, prospective Norwegian Moth
Pond water is used in everyday life by many people in Bangladesh, however, without sufficient and reliable information regarding water quality and pollution status. For this reason, geospatial analysis and mapping of water quality indices such as metal (MI), contamination (Cd), and physicochemical water quality index (WQI) were assessed to improve the understanding of potential pollution sources.
Kurskod: SANA14, 30 hp Terminsperiod 19 januari 2026 - 7 juni 2026 Obligatoriskt introduktionsmöteKursen startar med ett obligatoriskt introduktionsmöte. Du finner också tid och plats för detta och kommande föreläsningar genom att söka på kurskoden (SANA14) i schemat. Hitta ditt schema via TimeEdit.Du får fram gatuadressen i TimeEdit genom några knapptryck: klicka på adressen i kolumnen för Lokale
https://www.soc.lu.se/valkomstbrev-vartermin/valkommen-till-socialantropologi-grundkurs - 2026-07-15
Kurskod: SANA25, 30hp. Terminsperiod 19 januari 2026 - 7 juni 2026 Obligatoriskt introduktionsmöteKursen startar med ett obligatoriskt introduktionsmöte. Du finner också tid och plats för detta och för kommande föreläsningar genom att söka på kurskoden (SANA25) i schemat. Hitta ditt schema via TimeEdit.Du får fram gatuadressen i TimeEdit genom några knapptryck: klicka på adressen i kolumnen för Lo
https://www.soc.lu.se/valkomstbrev-vartermin/valkommen-till-socialantropologi-fortsattningskurs - 2026-07-15
Kurskod: SANK03, 30hp. Terminsperiod 19 januari 2026 - 7 juni 2026 Obligatoriskt introduktionsmöteKursen startar med ett obligatoriskt introduktionsmöte. Du finner också tid och plats för detta och för kommande föreläsningar genom att söka på kurskoden (SANK03) i schemat. Hitta ditt schema via TimeEdit.Du får fram gatuadressen i TimeEdit genom några knapptryck: klicka på adressen i kolumnen för Lo
https://www.soc.lu.se/valkomstbrev-vartermin/valkommen-till-socialantropologi-kandidatkurs - 2026-07-15
Existing research acknowledges users as an important external source of innovation for firms, but mainly focuses on user innovation in mature firms. The aim of this paper is to understand why and how startups strategically integrate users in the innovation process. To achieve this purpose we chose an abductive, qualitative research approach and conducted a multiple case study on six Swedish high-t
With an increasing focus on the national tests in Sweden, investigating how the tests affect teachers is highly relevant. The aim of this study is to provide further insight as to what role the national tests in English 5 and 6 play on teacher mindset, in order to allow for an informed evaluation of the role they play in assessment. This was achieved by a mixed methods approach, using both a quest
Discourse of reshoring as a possible risk mitigation strategy during times of uncertainty has during the recent decade become more prominent. This thesis examines the casual relationship between uncertainty and reshoring within the electrical manufacturing and pharmaceutical manufacturing industries in the U.S. The research question proposed is: How efficient are measures of uncertainty in predict
Objectives To investigate the possible impact of maternal obesity on ultrasonographic dating of pregnancy. Methods The Swedish Medical Birth Registry was used to identify 842 083 singleton pregnancies for which the estimated date of deliver), (EDD) according to last menstrual period (EDD-LMP) and according to ultrasound examination (EDD-US) and maternal body mass index (BMI) in early pregnancy wer
The purpose of the thesis is to investigate how the semiconductor industry will develop during the period 2007-2012. Issues: The main issues presented are: • How will the competitive landscape change from 2007 to 2012? • How will companies succeed in the industry in 2012? • What position will the Integrated Device Manufacturers take in the value chain in 2012? Method: In order to achieve the purpo
Development aid organizations are increasingly turning their focus on men and masculinities in the pursuit of women’s empowerment. Despite much effort to improve the lives of women, the hegemonic definition of empowerment in economic and individualistic terms have not been able to attack the unequal power structures between men and women, causing them to persist until this day. This essay explores
The purpose of this study is to investigate how peace and conflict within Nigeria can be understood. This is done by the application of a range of developmental indicators as well as theoretical variables drawn from the field of why insurgencies emerge. This study also includes the role of the Nigerian state in this dynamic. The applied method is a within-case comparison of three cases; the North
Sweden was once known for its open and generous refugee reception, with a mindset that was different from its neighbouring countries. However, this has changed in recent years. Due to an increased influx of people seeking asylum in Sweden, restrictive measures were put in place. The political discourse on migration shifted from a welcoming narrative to enforcing border controls and limiting access
Modern slavery is connected to the global trade and company supply chains. This essay aims to examine how this is regulated and addressed today, from a legal and corporate social responsibility (CSR) perspective, and analyse the extent to which such obstacles can be overcome. To reach the aim of this study, a traditional legal dogmatic method, together with an empirical method in the form of a cas
Purpose: This study intends to explore how video games companies work with strategic brand management. Methodology: A qualitative literature review and case study of Blizzard Entertainment using Kapferer’s Brand Identity Prism. The data was collected from Blizzard as well as other secondary sources. Findings: The findings of this paper shows that Kapferer’s Brand Identity Prism was applicable to t
