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The M protein of Streptococcus pyogenes is a major bacterial virulence factor that confers resistance to phagocytosis. To analyze how M protein allows evasion of phagocytosis, we used the M22 protein, which has features typical of many M proteins and has two well-characterized regions binding human plasma proteins: the hypervariable NH2-terminal region binds C4b-binding protein (C4BP), which inhib
Providing accessible, acceptable and appreciated public transport for elderly people is essential. This work studies the relation between elderly people’s preferences of standard factors in different public transport systems, and their physical capacity. Three public transport systems are focused, service route traffic, trunk route traffic and special transport service, which demand different capa
The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh
Ash is produced in combustion of biomass. Sonic part of this matter is called fly ash and is carried by the flow and causes not only air pollution and erosion, but also call affect the thermal radiation. The effects of fly ash particles oil the thermal radiation are considered ill this investigation. By analyzing sampled data in all electrostatic filter, a realistic particle size distribution is f
Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i
The contribution of civil society to quality of government is important to evaluate. Civil society is often touted as means to enhance quality of government and parallel to this idea the sector grown has substantially over time. Does civil society actually contribute to quality of government, and does civil society involved in expressive- or service functions differ in this regard? This is a quant
Background: All parents in Sweden are invited to child health service (CHS) parental groups, however only 49% of the families participate. The way the parental groups are managed has been shown to be of importance for how parents experience the support and CHS nurses describe feeling insecure when running the groups. Lack of facilitation, structure and leadership might jeopardise the potential ben
Abstract in Danish I dialog med Proust aktualiserer den franske forfatter Marcel Prousts betydning for Danmark. Afhandlingen leverer et nyt kapitel til dansk- litteratur- og åndshistorie. For første gang blotlægges den franske forfatters indvirkning på dansk litteratur og kultur. Det forsknings- og formidlingsmæssige sigte er at kaste lys over den påvirkning og indflydelse, som Prousts verdensberøI dialog med Proust actualizes the importance of the french writer Marcel Proust in Denmark. The dissertation brings a new chapter to the history of danish literature and history of thought. For the first time the significance and influence of Prousts world famous novel, À la recherche du temps perdu (1913-27) on Danish culture; on critics, writers and artists is revealed - from critic Kai Friis M
Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel
Risk analysis is important for safety-critical IT systems and services, both in public and private organizations. However, the actual practices and the challenges of risk analysis in these contexts have not been fully explored. This paper investigates the current practices of risk analysis by an interview-based investigation. This study investigates several factors of the risk analysis process, e.
"Foreword: The durability of building materials, especially the corrosion of reinforcement in concrete structures, has been a main research area in Scandinavia during the last decades. Results from many laboratories in the Scandinavian countries, and outside of Scandinavia, indicate that there are certain relationships between the service life and different concrete parameters, such as the water/b
Species extinction rates have during the last centuries reached levels leading scholars to proclaim a sixth mass extinction, even referred to as defining element of the Anthropocene. How humanity relates to nature and biodiversity has thus become part of how we delineate and describe the geological epoch we live in. Sustainability science has since its origins built on a research agenda calling fo
Spatial planning of Blue-Green Infrastructure (BGI) should ideally be based on well-evaluated and context specific solutions. One important obstacle to reach this goal relates to adequate provisioning of data to ensure good governance of BGI, i.e., appropriate planning, design, construction, and maintenance. This study explores the gap between data availability and implementation of BGI in urban p
De senaste åren har rättsfall och debatter gjort allmänheten uppmärksam på att våld som sker inom idrott behandlas annorlunda än våld i andra delar av samhället. Vissa tycker att ett självstyre inom idrotten vore lämpligt, medan andra tycker att man inom idrotten bör följa samma regler som alla andra. Syftet med den här uppsatsen är att utreda hur idrottsvåld tar sig uttryck i den svenska rätten sIn recent years, court cases and debates has brought attention to the fact that violence between athletes, from a legal point of view is treated differently than violence in other areas of society. Some favor autonomy for the world of sports and others think that athletes should follow the same rules as everyone else. The purpose of this essay is to examine how violence between athletes during org
Multimedia has become one of the cornerstones of our 21st century society and, when combined with mobility, has enabled a tremendous evolution of our society. However, joining these two concepts introduces many technical challenges. These range from having sufficient performance for handling multimedia content to having the battery stamina for acceptable mobile usage. When taking a projection of w
Brevmall Postadress CRC, Lunds universitet, Jan Waldenströms gata 35, Skånes universitetssjukhus SUS, 205 02 Malmö Besöksadress CRC, Jan Waldenströms gata 35, Skånes universitetssjukhus SUS, Malmö Telefon dir 040-391002, växel 040-391000 Telefax 040-391004 E- post hugh.connell@med.lu.se Internet http://www.medicin.lu.se Enhetenchef Med-serv i ce Beslut - tillfälliga riktlinjer för användning av lo
