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Objective: Needle acupuncture in small children has gained some acceptance in Western medicine. It is controversial, as infants and toddlers are unable to consent to treatment. We aimed to assess its efficacy for treating infantile colic. Design: A systematic review and a blinding-test validation based on individual patient data from randomised controlled trials. Primary end-points were crying tim
Aims: (i) Determine whether between-observer reproducibility for Ki67 when assessed on whole sections according to a standardized scoring protocol is adequate for clinical application. (ii) Compare between-observer reproducibility of Ki67 scores assessed on hot-spots to scores using a global method that averages across a tissue section.Background: The nuclear proliferation biomarker Ki67 has multi
The human population displays wide variety in demographic history, ancestry, content of DNA derived from hominins or ancient populations, adaptation, traits, copy number variation, drug response, and more. These polymorphisms are of broad interest to population geneticists, forensics investigators, and medical professionals. Historically, much of that knowledge was gained from population survey pr
Background: The purpose of this study is to validate a new five-tiered prognostic classification system to better discriminate cancer-specific mortality in men diagnosed with primary non-metastatic prostate cancer. Methods: We applied a recently described five-strata model, the Cambridge Prognostic Groups (CPGs 1-5), in two international cohorts and tested prognostic performance against the curren
Aim: To evaluate aerobic exercise in migraine and co-existing tension-type headache and neck pain. Methods: Consecutively recruited persons with migraine and co-existing tension-type headache and neck pain were randomized into an exercise group or control group. Aerobic exercise consisted of bike/cross-trainer/brisk walking for 45 minutes, three times/week. Controls continued usual daily activitie
We evaluated the performance of QuantiFERON-TB Gold Plus (QFT-Plus), which includes two Mycobacterium tuberculosis antigen formulations (TB1 and TB2), for detection of latent tuberculosis infection during pregnancy. Eight-hundred-twenty-nine Ethiopian pregnant women (5.9% HIV-positive) were tested with QFT-Plus, with bacteriological sputum analysis performed for women with clinically suspected tub
A search for a Higgs boson produced via vector-boson fusion and decaying into invisible particles is presented, using 20.3 fb−1of proton-proton collision data at a centre-of-mass energy of 8 TeV recorded by the ATLAS detector at the LHC. For a Higgs boson with a mass of 125 GeV, assuming the Standard Model production cross section, an upper bound of 0.28 is set on the branching fraction of H → inv
Background: Chronic low-grade inflammation and associated insulin resistance and metabolic abnormalities have been proposed as 'common soil' for diabetes mellitus (DM) and cardiovascular disease (CVD). This paper aimed to investigate the inflammatory profiles of DM and CVD and to distinguish their shared and specific markers. Methods: Based on the Malmö Diet and Cancer cohort, total and differenti
This article explores the similarities between the two most successful Swedish films of the past years. Through a focus on the two elderly protagonists the article discusses how the films acknowledge challenges in these men’s lives and in both contemporary and past society, but effectively repackage any serious issue in a form that remains palatable to audiences in Sweden and internationally. Them
Application of the Luttinger theorem to the Kondo lattice YbRh 2 Si 2 suggests that its large 4f-derived Fermi su
The objective is to estimate the number of deaths attributable to cardiovascular diseases and diet-related cancers that could be prevented or delayed in Sweden if adults adhere to the official dietary recommendations. We used an age-group and sex-specific epidemiological macro-simulation model to estimate preventable deaths due to the discrepancies between actual intake and recommended intake of c
Background: Recently, the block-sequential regularized expectation maximization (BSREM) reconstruction algorithm was commercially introduced (Q.Clear, GE Healthcare, Milwaukee, WI, USA). However, the combination of noise-penalizing factor (β), acquisition time, and administered activity for optimal image quality has not been established for
Introduction: Community Case Management (CCM) aims to improve health outcomes among children under five with malaria, diarrhea, and pneumonia, but its effectiveness in Malawi is limited by inconsistent standards of delivery characteristic of paper-based interventions. This may lead to negative impacts on child health outcomes and inefficient use of health system resources. This study evaluated the
This study analyses the influence of green roofs in different heights of the urban canopy layer: from the pedestrian level, up to 1m above the rooftop, in a social housing project in the South of Brazil. In order to quantify the cooling contribution of green roofs to the local microclimate, the housing project was simulated with ENVI-met 4.0 in the summer season. The variables used to assess the g
For several membrane separation processes, hollow fibre modules are either an already established or a promising type of module. Based on the analogy between mass and heat transfer, an engineering approach is proposed to estimate the shell-side mass transfer coefficient for axial flow in hollow fibre modules with due allowance for the void fraction. The approach enables one to take the entrance ef
Among concentrating solar power technologies, direct steam generation solar tower power plants represent a promising option. These systems eliminate the usage of heat transfer fluids allowing for the power block to be run at greater operating temperatures and therefore further increasing the thermal efficiency of the power cycle. On the other hand, the current state of the art of these systems doe
Context While vascular endothelial growth factor-targeted therapy and mammalian target of rapamycin inhibition are effective strategies in treating clear cell renal cell carcinoma (ccRCC), the most effective therapeutic approach for patients with non-clear cell RCC (non-ccRCC) is unknown. Objective To systematically review relevant literature comparing the oncological outcomes and adverse events o
Given the current energy crises, recent efforts have been directed at bringing energy efficiency and environmental awareness across the board into architectural education in Egypt. Although interest in sustainable design teaching and learning started more than 20 years ago at both post graduate and undergraduate level in Egypt, ecological illiteracy persists in architecture education. There is a l
