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The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. The GIP-induced increase in osteopontin expression was inhibited by the NFAT (the transcription factor
Background: Long-term exposure to air pollution is a hypothesized risk factor for ischemic stroke. In a large case-control study with a complete study base, we investigated whether hospital admissions for ischemic stroke were associated with residential concentrations of outdoor NOx, as a proxy for exposure to air pollution, in the region of Scania, Southern Sweden. Methods: We used a two-phase ca
Background: Cohort studies of the relationship between air pollution exposure and chronic health effects require predictions of exposure over long periods of time. Objectives: We developed a unified modeling approach for predicting fine particulate matter, nitrogen dioxide, oxides of nitrogen, and black carbon (as measured by light absorption coefficient) in six U.S. metropolitan regions from 1999
A bioanode with high current density and coulombic efficiency was developed by co-immobilization of pyranose dehydrogenase from Agaricus meleagris (AmPDH) with the dehydrogenase domain of cellobiose dehydrogenase from Corynascus thermophiles (recDHCtCDH) expressed recombinantly in Escherichia coli. The two enzymes were entrapped in Os-complex modified electrodeposition polymers (Os-EDPs) with spec
Background. Linear programming has been used extensively as a tool for nutritional recommendations. Extending the methodology to food formulation presents new challenges, since not all combinations of nutritious ingredients will produce an acceptable food. Furthermore, it would help in implementation and in ensuring the feasibility of the suggested recommendations. Objective. To extend the previou
In models of anomaly-mediated supersymmetry breaking (AMSB), the lightest chargino is predicted to have a lifetime long enough to be detected in collider experiments. This letter explores AMSB scenarios in pp collisions at root s = 7 TeV by attempting to identify decaying charginos which result in tracks that appear to have few associated hits in the outer region of the tracking system. The search
Follow-up methods must be easy for young people to handle. We examine Interactive Voice Response (IVR) as a method for collecting self-reported data. Sixty inpatients were recruited from a child and adolescent psychiatric emergency unit in Malmö, Sweden and called every second (N = 30) or every fourth (N = 30) day from discharge until first visit in outpatient care. A pre-recorded voice asked them
Background: In evaluating complex interventions, it is a challenge for researchers to provide transparent reporting of the intervention content with sufficient detail and clarity such that effects can be compared across studies or countries. Objective: To describe and compare the content of current rehabilitation for patients with inflammatory arthritis across 4 northern European countries. Patien
With the rise of serious environmental threats brought about by climate change, governments, organizations, leaders, and academics are constantly seeking ways to address this growing concern, and the development of a circular economy model is seen as a viable solution towards ensuring environmental sustainability alongside economic growth. The concept of circular economy has been defined in a mult
Title: The Carbon Impact of Component Production in China: Investigating the Impact of Carbon Border Adjustment Policies for a Global Manufacturing Company Authors: Fabian Bergman & Spiros Pavlidis Supervisor: Eva Berg, Lecturer at Engineering Logistics, Faculty of Engineering (LTH) at Lund University Examiner: Louise Bildsten, Associate Lecturer at Engineering Logistics, Faculty of Enginee
The research examines the effect of tonality on cross-border mergers and acquisitions (M&A) based on press release announcements. The impact of effective communication, tonality, and positive and negative words on the investor's behaviour and firm performance will be analysed to understand the impact on internal and external stakeholders. A comprehensive database of Swedish companies'
Under de senaste åren har transrättighetsrörelsen fått ökad spridning och uppmärksamhet både inom den queera rörelsen och i västvärlden och i media överlag. Debatter om att implementera ett tredje juridiskt kön för de personer som inte vill vara registrerade som man eller kvinna, och för personer födda med tvetydiga primära eller sekundära könsorgan, har ökat och nya policys implementeras i oIn recent years, the trans rights movement has gained a lot of traction and publicity both inside the queer movement and in western society and media at large. Debates on implementing a third legal gender for people who wish to not be registered as male or female, and for people born with ambiguous sex characteristics, have increased and new policies are being implemented in different countrie
Seeing how climate change disproportionately affects women and children, the voices of young people and women are vital to incorporate into discussions and decision-making processes regarding climate change. This thesis explores the experiences of young women in the climate movement who have participated at the COP climate conferences between 2015-2023. By drawing on the theoretical framework of f
Flow cytometry (FCM) is a powerful method for analysing cell characteristics, for cell quantification and for separation of different species. An automated FCM processing pipeline for lactic acid bacteria (LAB) was developed, and an analytical pipeline for co-cultures of LAB and Saccharomyces cerevisiae was designed. Data processing pipelines for Limosilactobacillus reuteri DSM 17938 sampled over
In the wake of the globalization, international tax planning structures has become vital for US investors in order to meet economic challenges and to survive on the competitive market. This research indicates that countries in Europe, such as Sweden and Switzerland, provide a favourable environment for US multinational corporations to set up holding companies as a way to enjoy benefits of legal ta
The quest for effectiveness and results has become a top political priority in the international development sector during the last decade. One of the prevailing tools for effectiveness and goal fulfilment for development projects is the Logical Framework Approach (LFA). Implementing organisations, such as NGOs, are often obliged to use the LFA for planning, implementation and evaluation in order
A confocal microscope is built to examine molecular powders, and in particular the (PhSn)_4S_6 cluster, that emits white light when irradiated with infrared laser light. The confocal microscope operating at long working distances is assembled and characterized. The components of the setup are first chosen according to requirements of the planned experiment. Thereafter, the microscope is assembled
