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Background Starting in the 1960s, a broad-based patients’ rights movement began to question doctors’ paternalism and to demand disclosure of medical information, informed consent, and active participation by the individual in personal health care. According to scholars, these changes contributed to downplay the biomedical approach in favor of a more patient-oriented perspective. The Swedish non-p
Endosomal entrapment is known to be a major bottleneck to successful cytoplasmic delivery of nucleic acids (NAs) using cationic liposome-NA nanoparticles (NPs). Quantitative measurements of distributions of NPs within early endosomes (EEs) have proven difficult due to the sub-resolution size and short lifetime of wildtype EEs. In this study we used Rab5-GFP, a member of the large family of GTPases
A hollow fiber supported liquid membrane module using one single fiber impregnated with a mixture of 1,10-dibenzyl-1,10-diaza-18-crown-6 and bis(2-ethylhexyl)phosphate dissolved in hexylbenzene was used for passive sampling of ppb levels of Pb(II), Cu(II), Zn(II), Mn(II), Ni(II), and Cd(II) in water. The target ions were simultaneously transported and preconcentrated into a citric acid acceptor so
Background: To study costs and outcome for serious hand and arm injuries during the first year after the trauma. Methods: In patients with a Hand Injury Severity Score (HISS) > 50, DASH and EQ-5D scores as well as factors related to costs within the health care sector, costs due to lost production and total costs were evaluated. Coxregression analysis stratifying for mechanism of injury was used t
We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - Septemb
Purpose: To assess baseline factors that may predict fast tibiofemoral cartilage loss over a 30-month period. Materials and Methods: The Multicenter Osteoarthritis (MOST) study is a longitudinal study of individuals who have or who are at high risk for knee osteoarthritis. The HIPAA-compliant protocol was approved by the institutional review boards of all participating centers, and written informe
Following the collapse of socialism in 1989, Eastern European countries experienced rapid socio-spatial reorganization causing a significant loss of urban greenspace (UGS). Greenspaces provide socio-environmental benefits, making them a crucial component of urban sustainability. This study explores the development of greenspace in Plovdiv (Bulgaria), which serves as a case study to understand disc
Intellectual Property Rights, IPR, are tools to incentivize innovation and investment in Research and Development (R&D) to promote growth and are traditionally used for economic interests before environmental and social concerns. The research project IPACST has developed a business tool kit for supporting organizations in designing their IP models to increase environmental and social impact. T
The main purpose of this thesis is to investigate the digital skills that are important for accountants in order to stay relevant in the era of digitalization. In addition, the research has two sub-purposes. The first sub-purpose is to study the digitalization-related training. Secondly, the thesis aims to explore the accountants’ opinions on the challenges associated with the digitalization in th
After more than a century of colonial subjugation by the United States, Puerto Rico’s stunted development model has finally collapsed. As a result, the island is currently facing one of the worst economic crises in its history. Despite the United States’ continued affirmation of its political dominance over Puerto Rico, it has largely placed the blame for the crisis on Puerto Ricans themselves, ac
People’s ability to learn holds a promise for sustainability as learning is seen to enable change; yet, the prevalence of norms and values in society that reinforce unsustainability may severely challenge this process. The debate on what role learning can play is centered around the question whether people can learn from others and if so, how to enhance it. More precisely, who has to learn what fr
Technology has revolutionized various industries, including the mobility sector. While many new mobility services have entered the market, the shift towards a more digitalised environment fostered the digital divide, making various mobility services more accessible for those that are tech-savvy. Especially elderly people however often face significant challenges adapting to new technologies. So fa
This thesis poses structural and behavioural competition problems in digital markets in terms of core platforms services provided by the gatekeepers under the proposed Digital Markets Act by the European Commission, where such problems are the most evident. This thesis analyses whether existing competition and more sector-specific legal tools are functional to address these problems. Traditional l
In the contemporary global context, the global focus on reducing environmental impacts in any formats has intensified. This study intends to assess the environmental impacts and life cycle costs associated with the A1-A5 stages (production and construction stages) of the Köping Port project and eight additional proposed scenarios. The Solidification/ Stabilization method along with the in-situ tec
Access to water is taken for granted in water abundant countries like Sweden, but safe water supply is increasingly threatened by droughts. This thesis analyses how the Swedish water sector responded to the unprecedented drought in 2018, by analysing water security discourse through the framework “What’s the problem represented to be?”. It explores implications of the drought on water policy and h
Women in developing countries have been and are still suffering from various disadvantages on the labor market. We use a fixed effects model with a hierarchical structure to assess the empirical relationship between economic integration, measured by trade, exports and imports, and the female labor force participation rate (FLFPR). The relationship between economic integration and the female employ
Sweden is often considered a global forerunner of family demographic shifts brought about by increasing individualization and globalization. While modern theories often depict a general movement away from romantic love sentiments and toward more rational, equal and casual exchanges and defamilization, feminist scholarship critiques the optimism of these claims in light of persisting structural ine
The Kyoto protocol was the first tangible approach to prevent increasing amounts of greenhouse gases in the atmosphere. In order to attain this objective, the parties of the protocol decided to put restrictions on anthropogenic emissions caused by production in developed countries. This territorially defined production-based method of measuring might have been a misguided path though. Researchers
Climate change represents one of the most serious threats to international environmental, social and economic security. The growing energy consumption is producing enormous amounts of carbon dioxide (CO2) emissions, which are fastening climate change and polluting the environment. For this reason, the European Union (EU) desires to act as a global leader in combating climate change and is therefor
The RAINBOW program, a Child and Family-Focused Cognitive Behavioral Therapy program (CFF-CBT) for Pediatric Bipolar Disorder (PBD) designed for children aged 8-12 years and their parents, in a parallel group format, has been adapted to adolescents aged 14-17. The aim of this study was to investigate if CFF-CBT is effective and feasible for adolescents and their parents in Sweden. Method: The samp
