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High flux, monolithic water purification filters based on polylactic acid (PLA) functionalised with fish scale extracted hydroxyapatite (HAp) were prepared by solvent-assisted blending and thermally induced phase separation (TIPS), followed by twin-screw extrusion into filaments and processed via three-dimensional (3D) printing. The printed filters with consistent pore geometry and channel interco
Ongoing climate variability and change are increasing the burden of diarrhoeal disease worldwide. Meaningful early warning systems with adequate lead times (weeks to months) are needed to guide public health decision–making and enhance community resilience against health threats posed by climate change. Toward this goal, we trained various machine-learning models to predict diarrhoeal disease rate
BACKGROUND Reusing anaesthesia infusion-set components may reduce the climate impact from plastic waste and discarded medications. Infusion-set contents can be shielded from patient contact by single use of an infusion line fitted with dual antireflux valves, preventing retrograde entry of microorganisms, and eliminating the risk for patient-to-patient cross-contamination. However, infusion-set co
Dimethyl ether (DME) is promising as an additive for co-firing with ammonia (NH3) to solve the problem of its low reactivity combustion. However, the combustion modeling of blended fuels is challenging, and previous efforts primarily relied on the adjustment of rate constants for key reactions to bridge the gap between experiments and simulations. In the present work, ab initio kinetic studies wer
Design thinking is an innovative methodology that may be applied by small and medium enterprises which emphasizes a human-centered approach to problem-solving, facilitating the creation of novel solutions for complex and open-ended challenges like the development of new products. Despite its recognized importance in business and academia, many industrial SMEs struggle with applying design thinking
In this study, a combined workflow of computational methodologies is introduced to explore the transformative landscape of the ancient city of Savatra (Central Anatolia Region, Türkiye), which faces long-term risks stemming from natural and anthropogenic threats. Emphasis was placed on regional and local scale landscape analysis, employing aerial and ground-based remote-sensing techniques to unrav
Synaptogenesis, the formation of functional synapses, is a crucial step for the development of the central nervous system. Among the genes involved in this process are cell adhesion molecules, such as protocadherins and neuroligins, which are essential factors for the identification of the appropriate partner cell and the formation of synapses. In this work, we studied the expression and the genet
With the post-Kyoto climate negotiations underway, global emissions must be cut by 66% by, 2050 according to the IPCC, to prevent further damage to the environment. In order for this emission cut to be possible, all nations have to be a part of these negotiations. The Kyoto Protocol and the UNFCCC is the natural starting point for a new climate regime that must be established. Through a literatur
Concerto for Double Bass and Orchestra by Eduard Tubin is considered to be one of the most challenging pieces of the double bass repertoire as it is known to be a physically demanding work. It was written for double bass player Ludvig Juht who was a physically big built man and welcomed the technical challenges. This thesis aims to analyze these challenges of the piece for a player with smaller ph
With his notion of original affirmation, Paul Ricoeur wishes to reinstate the primacy of being over nothingness, joy over anguish, and affirmation over negation. Having adopted the term from Jean Nabert, he draws from the tradition of French reflective philosophy to formulate his conception of the originally affirmative nature of existence. Ricoeur argues that positive values can be found in and t
This study aims to identify the most cost-effective and environmentally friendly retrofit solutions for enhancing the energy efficiency of second homes in Sweden. Second homes, often used intermittently throughout the year, represent a significant portion of residential energy use and carbon emissions. Therefore, optimizing energy consumption in these homes is critical for achieving national and g
Soil moisture (SM) is an essential climate variable that controls fundamental hydrological and climatic processes. Soil moisture products derived from microwave remote sensing often provide measurements at low spatial resolution and incomplete temporal records. This thesis presents a novel method for estimation soil moisture at both high spatial and temporal resolution by using a deep learning rec
The e-commerce sector in the modern, digital age is an increasingly important component of the global economy. For the European union, coping with this emerging market has meant regulatory challenges in several legislative areas, not least in the field of taxation. One of the most recent initiatives in removing obstacles for the e-commerce is the so-called VAT e-commerce package. The VAT e-commer
Electric cars are by many considered a sustainable solution to the ever-growing demand for road vehicles and fuel. The transportation sector is responsible for almost a third of the total greenhouse gas emissions globally and approximately 80% of these emissions can be attributed to road vehicles. Thus, there is an urgent need for a shift away from fossil fuels in the sector. While the consumer in
A novel multi-source data fusion method based on Bayesian inference (BIF) was proposed in this study to blend the advantages of in-situ observations and remote sensing estimations for obtaining accurate chlorophyll-a (Chla) concentration in Lake Taihu (China). Two error models (additive and multiplicative) were adopted to construct the likelihood function in BIF; the BIF method was also compared w
The aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill non-bleeding adult patients without liver failure or anticoagulation treatment, with Owren PT > 1.2, who were prescribed intravenous vitamin K1. Blood was drawn at baseline and at 20–28 h after vitamin K1 administratiThe aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill non-bleeding adult patients without liver failure or anticoagulation treatment, with Owren PT > 1.2, who were prescribed intravenous vitamin K1. Blood was drawn at baseline and at 20–28 h after vitamin K1 administrati
Recent advances in cell reprogramming have made it possible to form new therapeutic cells within the body itself via a process called direct conversion or lineage reprogramming. A series of studies have shown that it is possible to reprogram resident glia into new neurons within the brain parenchyma. These studies opened up for the targeted attempts to achieve functional brain repair using in vivo
