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Aims: Iron deficiency (ID) is comorbid in up to 50% patients with heart failure (HF) and exacerbates disease burden. Ferric carboxymaltose (FCM) reduced HF hospitalizations and improved quality of life when used to treat ID at discharge in patients hospitalized for acute HF with left ventricular ejection fraction <50% in the AFFIRM-AHF trial. We quantified the effect of FCM on burden of disease an
Objectives To retrospectively evaluate ophthalmological and neurological outcomes in a Swedish cohort of infants born before 24 weeks gestational age (GA) and explore risk factors for visual impairment. Setting Eye and paediatric clinics in Sweden. Participants Infants screened for retinopathy of prematurity (ROP) (n=399), born before 24 weeks GA, 2007-2018. Cases were excluded if ophthalmological
Evaporation is one of the main components of the hydrological cycle, and its estimation is crucial and important for water resources management issues. Access to a reliable estimator tool for evaporation simulation is important in arid and semi-arid areas such as Iran, which lose more than 70% of their received precipitation by evaporation. Current research employs the Bayesian Regularization (BR)
Packaging can play a key role in reducing food waste and enabling resource efficient logistics operations. This paper offers insights into why this potential is not fully adopted by companies in food supply chains by exploring adoption barriers for sustainable packaging practices in ten companies in South Africa and Sweden. The paper develops an analytical framework from theory and applies it to t
Side-channel resilience is a crucial feature when assessing whether a postquantum cryptographic proposal is sufficiently mature to be deployed. In this paper, we propose a generic and efficient adaptive approach to improve the sample complexity (i.e., the required number of traces) of plaintext-checking (PC) oracle-based sidechannel attacks (SCAs), a major class of key recovery chosen-ciphertext S
Trots att jordbrukets näringsutsläpp till Östersjön har minskat krävs mycket mer för att uppnå de uppsatta miljömålen. Vi har utvärderat politiken som används för att minska utsläppen från de nio länder som samarbetar om restaureringen av Östersjön. Vi finner att den nuvarande politiken är otillräcklig eftersom:Många länder har inte genomfört de utlovade åtgärderna för att minska näringsutsläpp fr
PURPOSE: Dynamic glucose-enhanced (DGE) MRI relates to a group of exchange-based MRI techniques where the uptake of glucose analogues is studied dynamically. However, motion artifacts can be mistaken for true DGE effects, while motion correction may alter true signal effects. The aim was to design a numerical human brain phantom to simulate a realistic DGE MRI protocol at 3T that can be used to as
This article introduces the Framework for Integrating Rights and Equality (FIRE): a transdisciplinary framework that builds synergies between human rights-based (HRBA) and gender equality approaches to disaster risk reduction (DRR) and climate change adaptation (CCA). It describes how FIRE has been developed, tested and refined over the course of a five-year regional learning and technical coopera
With the urgent demand for ultralow-temperature refrigerators worldwide, the operation reliability and stability of the refrigeration system becomes greatly crucial. In this study, a -80 oC ultralow-temperature cascade refrigeration system (CRS) is developed. From aspects of global warming potential (GWP) and ozone depletion potential (ODP), the environmentally friendly refrigerants R290 and R170
The atmospheres of ultra-hot Jupiters are highly interesting and unique chemical laboratories. Due to the very high atmospheric temperatures, their chemical composition is dominated by atoms and ions instead of molecules, and the formation of aerosols on their day-sides is unlikely. Thus, for these planets detailed chemical characterisations via the direct detection of elements through high-resolu
In ultrafast spectroscopy, the temporal resolution of time-resolved experiments depends on the duration of the pump and probe pulses, and on the control and characterization of their relative synchronization. Free-electron lasers operating in the extreme ultraviolet and X-ray spectral regions deliver pulses with femtosecond and attosecond duration in a broad array of pump–probe configurations to s
Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia
BACKGROUND: Shared decision-making (SDM) between clinicians and patients is one of the pillars of the modern patient-centric philosophy of care. This study aims to explore SDM in the discipline of trauma and emergency surgery, investigating its interpretation as well as the barriers and facilitators for its implementation among surgeons.METHODS: Grounding on the literature on the topics of the und
Background: Primary healthcare providers are increasingly challenged in supporting patients with psychosocial needs. Arts on Prescription (AoP) has been shown to improve primary healthcare patients’ mental health wellbeing. The aim of the current study is to understand the psychosocial effect of participating in an Arts on Prescription programme. Methods: A total of 112 primary healthcare patients
Background: Lung injury in COVID-19 is characterized by neutrophil invasion and the release of neutrophil extracellular traps (NETs). An aberrant NET formation may induce local inflammation and increase sputum viscosity. Inhalation of DNase I (dornase alfa) is a treatment option that degrades NETs in the airways. Previous case series have indicated positive clinical effects of inhaled dornase alfa
District heating and cooling is a simple but powerful technology that could contribute to decarbonising Europe's heating and cooling supply. However, its current overall penetration is minor. Furthermore, future systems could adopt different configurations with various settings of temperature levels or production location. This thesis has aimed to improve existing tools to evaluate district heatin
