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Purpose: In a multicenter prospective cohort study, we assessed the diagnostic yield of the Nordic guidelines for germline investigation in myeloid neoplasms and mapped the spectrum of inherited and somatic variants. Experimental Design: Eighty-five patients (acute myeloid leukemia, n = 38; myelodysplastic syndromes, n = 26; thrombocytopenia, n = 14; and other, n = 7) fulfilling the Nordic criteri
Casein micelles are key structures in milk, influencing stability, nutritional properties, and functionality. Their hierarchical architecture, which is dynamic and responsive to environmental conditions, plays a crucial role in dairy processing. Understanding the structural and dynamic properties of casein micelles is essential for optimizing dairy products and processing techniques. This study pr
Purpose: Radiation therapy (RT) causes tissue damage and inflammation. Because cytokines play a key role in such processes, their expression levels can be an indicator of cell and tissue toxicity. This critical review aims to explore whether levels of circulating inflammatory biomarkers in peripheral blood are associated with proton- or photon-based therapy in the pelvic area and how these levels
Educational development initiatives in the form of short-lived, isolated pedagogical courses may at best change the thinking and practice of a few pioneers, and then perhaps only temporarily. It is only possible to successfully address the need that such initiatives are intended to meet if the impact is lasting and effects a cultural change locally at the university. In this study, we look beyond
Robots, which were seen as gimmicks in science fiction stories until not so long ago, have already crossed into reality. Thanks to the ever-growing autonomy of robots and ever-expanding variety of roles assigned to them, they are becoming more integrated into the ordinary course of everyday life. With the advent of social robots that can engage human beings on personal levels, for the first time,
Human-induced climate change has emerged as one of the greatest sustainability challenges of our time, with significant risks for human health, livelihoods and security. However, technological solutions to phase out the use of fossil fuels in industrialized countries are politically contested. Their adoption depends on disrupting the institutions and behaviours that perpetuate the dependence on fo
The goal of this thesis work is to implement a convolutional neural network on an FPGA device with the capability of recognising human sign language. The set of gestures that the neural network can identify has been taken from the Swedish sign language, and it consists of the signs used for representing the letters of the Swedish alphabet (a.k.a. fingerspelling). The motivation driving this projec
This thesis evaluates the performance of an EPR programme for post-consumer PET waste management by PET recycling company (PETCO) in South Africa. It analyses waste management policies of South Africa that are relevant to EPR. Using a set of evaluative tools, the thesis reveals areas for improvement in the EPR scheme. It also identifies areas in informal sector interventions where EPR can contribu
Today, Swedish police authorities nationwide collect data of traffic accidents. The information is stored in a national database managed by the Swedish Transport Agency and is an important resource in the process of analysing and improving road safety. Literature studies in this thesis, together with earlier work by the author have suggested that the data collection process is in need of an upda
Nature-based Solutions (NBS) are one of the approaches to the regeneration of urban areas. These solutions are copied from, inspired by, or supported by nature. The solutions, ideally, result in multiple benefits to the society and environment. The examples of NBS measures for stormwater management are, including but not limited to, natural swale, retention ponds, and green roofs. Such measures ha
This study was motivated by the current vulnerable status of Chinese taught as a second language in Swedish gymnasium education, calling for further knowledge on how theories on second language (L2) acquisition can benefit instruction on L2 Chinese. Since language textbooks often constitute the curriculum in Swedish classrooms, two Chinese textbooks were targeted for analysis in terms of the seque
In the face of climate change, governments in the Global North have decided on various decarbonisation plans. With the transport sector causing more than a quarter of the global greenhouse gas emissions, its decarbonisation has become a central debate. Yet, plans for a sustainable mobility system are largely focused on local and regional scales, neglecting the global entanglements of the supply ch
Abstract Title: An exploratory study of sourcing options for alternative materials to leather. Authors: Akashdeep Maheshwari and David Marriaga Diaz – Master Students in Logistics & Supply Chain Management. Division of Engineering Logistics. Lunds Tekniska Högskola (LTH), Lund University. Thesis supervisors: Caroline McGarvey – Sustainability Manager / Material and Innovation Deployment Lead
In recent years, Iceland has experienced a growing demand for residential housing and the average square-meter price for apartments and single-family homes in the Capital Region has almost doubled between 2010 and 2019. Property sales in Iceland are most commonly intermediated by real estate brokers and the sales process stands in contrast to other Nordic countries, since it involves a bidding pro
Popular Abstract in Swedish Avstår barn i fattiga länder från utbildning framförallt för att de är fattiga eller för att de upplever att skolan inte har något meningsfullt att erbjuda? Svaret på den frågan har stor betydelse för vilken politik som bör föras. Ett empiriskt bidrag till en sådan frågeställning är i vilken utsträckning som utbildning kan tänkas vara ett ?lönsamt? alternativ för indiviWhy do some children in the developing world choose to stay out of school? Is it mainly because poverty leaves them with no options or because schooling seems to offer them few benefits? The answers to these questions have profound policy implications. An empirical input into this discussion is the extent to which schooling can actually be perceived as a profitable option in various countries and,
With the attempts to achieve higher thermal efficiency, turbine blades are exposed to very high temperature gases and may undergo severe thermal stress and fatigue. Thus, in order to develop optimal cooling strategies and reduce the heat transfer it is important to obtain a good understanding of both the complex flow field and the heat transfer characteristics in turbine rotor/stator hot-gas passa
In the Nordic Reference Interval Project 2000 (NORIP) serum, Li-heparin plasma and EDTA buffy coat were collected at 102 laboratories in 5 Nordic countries from healthy individuals aged 18 years or more and evenly distributed for laboratory, gender and age. Multiple aliquots of these samples from each of about 3000 persons are now stored at the Nordic Reference Interval Project Bio-bank and Databa
A generalized scattering matrix method is presented for spin-dependent electron transport in a quantum waveguide under the modulations of local magnetic field and/or spin-orbit interaction (SOI). All the required Hamiltonian matrices are expressed in terms of a common basis spanned by the products of the transverse spatial eigenstates and the spin eigenstates of the leads. In the formulation we ha
Objectives To study early-onset group B streptococcal (EOGBS) morbidity, mortality, and maternal risk factors. Design Observational, population-based, retrospective. Data from national registers and medical records. Setting Sweden, 1997-2001. Population Cohort of 640 infants with a diagnosis of GBS infection out of 435 070 live births. Method Infants with diagnoses GBS sepsis (P36.0) and/or pneumo
