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Purpose: In 2017, the Geneva Alzheimer’s disease (AD) Biomarker Roadmap initiative adapted the framework of the systematic validation of oncological diagnostic biomarkers to AD biomarkers, with the aim to accelerate their development and implementation in clinical practice. With this work, we assess the maturity of [18F]flortaucipir PET and define its research priorities. Methods: The level of mat
Äldre anställdas ställning på arbetsmarknaden är onekligen osäker. I detta arbete försöker jag att räta ut och förstå hur äldre arbetstagare är skyddade på arbetsmarknaden genom att undersöka hur gällande rätt är designat. Detta görs genom en komparativ studie mellan Sverige och Kina, där en rad olika undersökningsområden kopplat till anställningsskydd för äldre bearbetas. Arbetet berör och förklaThe status of the elderly on the labour market is undeniably precarious. In this thesis, I am trying to straighten out how the elderly are protected on the labour market and how the legislation to protect them is designed. This is done through a comparative study between Sweden and China, where a number of research areas associated with employment protection for elderly are processed. I am, in thi
The global pandemic of Covid-19 has drastically changed the behaviour of citizens around the world. This research aims to identify actions that ensure low-carbon, inclusive forms of mobility that respond to the behavioural changes during Covid-19. The city of Hamburg, Germany, and its problems with transport-related emissions and socio-economic inequalities serve as a representative case study. Th
Background: Well-established associations exist between the risk of small for gestational age (SGA) and unidimensional sociodemographic factors. We investigated social inequalities in SGA risk and adopted an intersectional approach that simultaneously considers different social categories. By doing so, we could assess heterogeneities in SGA risk within unidimensional sociodemographic categories. M
Family caregivers in palliative care have a need for knowledge and support from health professionals, resulting in the need for educational and supportive interventions. However, research has mainly focused on the experiences of family caregivers taking part in interventions. To gain an increased understanding of complex interventions, it is necessary to integrate the perspectives of health profes
In Sweden the Sami people is a national minority of indigenous people. Traditionally they are living in northern Sweden but can be found all over the country. The Church of Sweden has a long tradition of giving church services using the native Sami language in the Swedish part of Sapmi, the Sami people name of their land. The problem of recruiting Sami speaking clergy has always been great and dif
The EU has over the years tried to implement a common European identity to legitimize its increased sovereignty in Europe. In present time, nationalist movements have been assembling in European countries which seem to contradict the aimed effect of the European identity. This thesis examines the outspoken nationalist group Identity and Democracy in the European Parliament and how they portray the
This thesis attempts to understand how digital representations of the body understand and mediate the digital and Real body. In order to approach this inquiry, this thesis will engage with and compare debates regarding the semiotic register of the index, and how it has been understood in relation to analogue photography versus digital media. This inquiry will be guided by an investigation into the
The intensification of forest management over the recent decades, in combination with the effects of a warming climate, leaves forestry and forest management with the challenging task of maintaining forest ecosystems’ further abilities to provide ecosystem services. By systematically reviewing peer- reviewed academic literature this study analyzes the concept of multifunctionality and its applicat
Trinidad and Tobago is a country with a long history in the hydrocarbon industry. This makes the country one of the wealthiest in the Caribbean region and most poised to be at the edge of innovation and sustainable technology use. However, unsustainable urban development practices have resulted in increasing negative impacts. Governments world-wide have been introducing policies and regulations to
Background In the surroundings of the Dadaab Refugee Camps in Kenya lives a large pastoral population under less favourable conditions than the people inside the refugee camps. Many international NGO’s have started to support the hosting community, but there seems to be a lack of long term oriented development work. This project is based on a wonder over why it apparently is difficult for an inter
Hip-related pain is a well-recognised complaint among active young and middle-aged active adults. People experiencing hip-related disorders commonly report pain and reduced functional capacity, including difficulties in executing activities of daily living. Patient-reported outcome measures (PROMs) are essential to accurately examine and compare the effects of different treatments on disability in
The Tsenkher structure in the Gobi-Altai, Mongolia is a c. 3.7 km diameter crater with a well-preserved ejecta blanket. It has been hypothesized to be either of impact or volcanic origin in our previous work. Observations during our 2007 expedition and related sample analyses give further support for an impact origin. The evidence includes the presence of a structurally uplifted near-circular rim
Background: Despite the promising evidence of health-promoting and preventive interventions for maintaining health among older people, not all interventions can be implemented due to limited resources. Due to the variation of content in the interventions and the breadth of outcomes used to evaluate effects in such interventions, comparisons are difficult and the choice of which interventions to im
Gambling disorder is associated with severe financial, social, and psychological consequences, but treatment-seeking rates have been described to be low. Apart from formal treatment, motivational interventions in nontreatment-seeking high-risk gamblers have been shown to be promising. However, little is known about the effectiveness and acceptability of such motivational interventions carried out
The impact of the microbiota on our health is rapidly gaining interest. While several bacteria have been associated with disease, and others being indicated as having a probiotic effect, the individual biomolecules behind these alterations are often not known. A major problem in the study of these factors in vivo is their low abundance in complex environments. We recently identified the first secr
This review examines the current status of knowledge of sepsis and pneumonia in the elderly population and how the dynamics of the pulmonary challenge affects outcome and consequences. Led by an unprecedented shift in demographics, where a larger proportion of the population will reach an older age, clinical and experimental research shows that aging is associated with certain pulmonary changes, b
