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Deep learning is a machine learning technique inspired by the biological nervous system. The method has been used more and more over the last decades. Within this thesis, convolutional neural networks (CNN:s) are used for Gleason classification of prostate cancer in histopathological images. The data that has been used consists of digitalized microscopic images of prostate biopsies stained with ha
Drought is projected to increase in frequency and intensity and impacts trees with increased water stress and increased mortality rate. Water stresses can cause hydraulic failure-related mortality or carbon starvation due to tree species having different strategies to deal with water stresses. LPJ-GUESS-HYD (Hydraulic implementation of a new plant hydraulics scheme in LPJ-GUESS) was developed to i
The purpose of this paper is to predict the cost-effectiveness of a preventive health care project based on physical exercise that will take place at Medicon Village, Lund, in the fall of 2016. Data from the Health Survey for England is used to develop an empirical model with individual fixed effects that estimates the relationship between physical exercise and psychological well-being. The freque
This study evaluated the sample sizes necessary to estimate several soil and vegetation characteristics within 10% confidence intervals with 95% probability in three terra firme tropical rainforest sites. Across all three plots, the most spatially heterogeneous variables were measurements of total standing crop root mass, ground surface litter mass, litter fall, root growth and soil respiration wh
The modelling of damage effects in materials constitutes a major challenge in various engineering-related disciplines. However, the assumption of purely local continuum damage formulations may lead to ill-posed boundary value problems and—with regard to numerical methods such as the finite element method—to mesh-dependent solutions, a vanishing localised damage zone upon mesh refinement, and hence
In this paper, a novel multiple representation data structure for dynamic visualisation of 3D city models, called CityTree, is proposed. To create a CityTree, the ground plans of the buildings are generated and simplified. Then, the buildings are divided into clusters by the road network and one CityTree is created for each cluster. The leaf nodes of the CityTree represent the original 3D objects
The three-year research project funded by MSB applies design science, in combination with traditional scientific investigation, to develop a method to guide the planning phase of capacity development projects for disaster risk reduction and climate change adaptation. The method facilitates local participation and ownership as it builds on the strengths of the Logical Framework Approach (LFA), whil
Isotropic chiral media can be modelled in several ways. We show that when realizing such a medium from spiral inclusions with real permittivities and permeabilities in a periodic structure, a modified Drude–Born–Fedorov model is obtained. This model equals the original Born model for small wave vectors, but the strength of the chirality depends on the propagation direction. The effective parameter
We present the design of a split-and-delay unit for the production of two delayed replicas of an incident extreme ultraviolet (XUV) pulse. The device features a single grazing incidence reflection in combination with attenuation of remaining infrared light co-propagating with the XUV beam, offering a high throughput without the need of introducing additional optics that would further decrease the
Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnose
The late Eocene may have been a period with an enhanced flux of extraterrestrial matter to Earth related either to a comet or an asteroid shower. The evidence comes from two very large and several medium-sized impact craters, at least two microtektite-microkrystite layers, and a stratigraphic interval with enhanced extraterrestrial He-3, all within the period ca. 36.3-34.3 Ma. Here, we show that t
Comparisons have revealed large discrepancies among the many methods for measuring soil CO2 efflux indicating the need for an absolute calibration of methods. This study presents a calibration system, constructed to imitate an area of soil, and its application to two different chamber systems for the measurement Of Soil CO2 efflux: one open and one closed dynamic. Air rich in CO2 was allowed to di
We report on the applications of a single-longitudinal-mode (SLM) pulsed alexandrite laser system for diagnostics of parameters of flow/combustion interest. The laser system is characterized by its narrow linewidth, high peak power, and broad tunablity. The absolute frequency of the laser output was monitored by a wavelength diagnostic system, which included a high-resolution confocal etalon and a
The COST/IWA benchmark simulation model has been available for seven years. Its primary purpose has been to create a platform for control strategy benchmarking of activated sludge processes. The fact that the benchmark has resulted in more than 100 publications, not only in Europe but also worldwide, demonstrates the interest in such a tool within the research community In this paper, an extension
Profilins are small, widely expressed actin binding proteins, thought to be key regulators of actin dynamics in living cells. So far, three profilin-genes have been described: profilin-I (PFN1), profilin-II (PFN2) with two splice variants and the recently identified profilin-III (PFN3). Here we describe the genomic organization of the genes encoding human and mouse profilin-III. Both are single ex
A previously presented robust and fast diagnostic NOx model was modified into a predictive model. This was done by using simple yet physically based models for fuel injection, ignition delay, premixed heat release rate and diffusion combustion heat release rate. The model can be used both for traditional high-temperature combustion and for high-EGR, low-temperature combustion. It was possible
A shift in business thinking from selling products to providing service solutions to customer needs is becoming noticeable. It is driven by increasing competition and the need to identify new profit centres for producers of mature products. This paper identifies a new product group that could be interesting from the product-service system perspective - baby prams. The study presents a new business
Current internal radiation dosimetry models for the small intestine, and for most walled organs, lack the ability to account for the activity uptake in the intestinal wall. In existing models the cross-dose from nearby loops of the small intestine is not taken into consideration. The aim of this investigation was to develop a general model for calculating the absorbed dose to the radiation-sensiti
