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Islet autoantibodies are currently used to classify type 1 diabetes at diagnosis as they reflect the autoimmune pathogenesis of the disease. The presence of maternal autoantibodies reactive with pancreatic islet antigens is thought to increase the risk for type 1 diabetes in the offspring. The objective of this study was to determine seroconversion to islet autoantibodies in non-diabetic mothers d
The type and potency of an immune response provoked during vaccination will determine ultimate success in disease prevention. The basis for this response will be the design and implementation of antigen presentation to the immune system. Whereas direct antigen administration will elicit some form of immunological response, a more sophisticated approach would couple the antigen of interest to a vec
Vårt mål är att öka kunskapen om demens- och minnessjukdomar - alltifrån uppkomst till behandling. Forskningen omfattar ett flertal diagnoser, bland annat Alzheimers sjukdom, Lewy Body demens och Parkinsons sjukdom. Markörer och tidig upptäckt av Alzheimer, genom bland annat ryggvätskeprov, är ett styrkeområde där vi uppnått resultat som omsatts i daglig, klinisk användning. Genom innovativ använWe embrace the big picture of dementia and memory diseases. This includes the course from origin and early detection to treatment. The scope includes a wide range of diagnoses, among these Alzheimer’s Disease, Lewy Body Dementia and Parkinson’s Disease. Early detection of Alzheimer’s Disease, by using new markers, is one of our most promising fields. Spinal fluid test concepts, developed by us, ar
Avdelningen forsknings- och externkommunikation har följande ansvarsområden: forskningskommunikation, innehållsproduktion, samt redaktion och medierelationer.The Research and External Communication unit has the following areas of responsibility: research communication, content production, editorial activities and media relations.
Mjukdelssarkom utgör en heterogen grupp av ovanliga tumörer och innefattar ett 50-tal olika subtyper med varierande klinisk bild och prognos. Två tredjedelar är höggradigt maligna tumörer och en tredjedel av patienterna avlider i tumörsjukdom. I Södra sjukvårdsregion är vården av patienter med sarkom centraliserad till SUS/Lund. Sarkomgruppen i Lund utreder och behandlar patienter med sarkom och Soft tissue sarcomas constitute a heterogeneous group of rare tumours with some 50 histopathologic types with different clinical characteristics and prognosis. Two thirds are highly malignant tumours and one third of the patients die due to metastatic disease. The care of sarcoma patients in the Southern Swedish health care region is centralised to the Lund Sarcoma Centre. We have a large data ba
The remarkable growth of e-commerce has defined the recent years of various industries worldwide. Driven by consumers, the e-commerce surge (e-retail in particular) stems from the final leg of the supply chain: the last mile. As the growing flow of e-commerce orders continues to generate new records for annual revenues, key actors in the last mile face the challenges of increasing customer demands
IntroductionEmerging evidence suggests a difference in access to facilities for medical termination of pregnancy (MTP) and delivery among women in different regions of the country. However, we lack assessments at a large scale across all geographies. Our study aims to describe the percent contribution of private and public sectors in institutional deliveries and MTP in India.MethodsA secondary dat
Objective: The objective of this study is to study the fetal scalp temperature (FST) and maternal axillary temperature (MAT) during vaginal delivery relative to progression of labor, uterine contractions (UC) and epidural analgesia (EDA), and to construct normal temperature reference ranges related to stage of labor. Material and methods: Temperatures were recorded continuously in labor of 132 wom
Maligna lymfom är tumörer utgående från immunsystemet. De innefattar ca 50 olika undergrupper med vitt skilda kliniska förlopp. Målet för vårt arbete är att förbättra överlevnad och livskvalitet för patienter med maligna lymfom, också med hänsyn tid långtidseffekter av behandling, samt att förbättra metoder för diagnostik och prognostik för dessa sjukdomar. Vår grupp har sedan många år bedriviThe area of research for our group is malignant lymphomas – aiming for the improvement of the quality of life and survival of these patients. The paradigm behind most of current health care is evidence –based medicine. The evidence basis is primarily derived from clinical trials, but data can also be extracted from alternate sources such as national or regional data registries. The objective of ou
AIMS: The oncological, surgical and cosmetic results, patient satisfaction and psychological morbidity of immediate breast reconstruction following mastectomy for breast cancer were evaluated. METHODS: From 1980 to 1994, 79 immediate breast reconstructions were performed in Malmo. From 1985 immediate breast reconstruction was performed in 21% of mastectomies among patients
High-resolution video generates substantial volumes of data that exceed typical network transmission capabilities, forcing a trade-off between video quality and bandwidth constraints. This thesis explores region-based compression techniques for sports video that intelligently allocate bits based on visual importance, preserving quality where it matters most while reducing bandwidth in less critica
Vi utvärderar behandlingsmetoder för svårbehandlade psykiatriska tillstånd, med målet att förbättra behandlingsresultat och klinisk praxis. KetECT-studien, som jämförde ketamin med elektrokonvulsiv terapi (ECT) vid unipolär depression, har bidragit till att ketamin nu är ett alternativ för vissa patienter. Blodprover och kognitiva data från KetECT kommer att analyseras för att identifiera biomarköWe evaluate treatment methods for refractory psychiatric conditions, aiming to improve outcomes and clinical practice. The KetECT study, which compared ketamine with electroconvulsive therapy (ECT) in unipolar depression, has led to ketamine being considered an alternative for certain patients. Blood samples and cognitive data from KetECT will be analyzed to identify biomarkers that can predict tr
I kompetenscentret Sentio kopplas excellent forskning och innovation vid universitet, företag och forskningsinstitut samman för att realisera visionen om ett världsledande centrum för utveckling av banbrytande integrerad sensorteknologi som möjliggör digital realtidsoptimering av industriella produkter och produktionsprocesser för en hållbar industri. Genom kontinuerlig och smart processoptimerinThe Sentio Competence Centre collects all necessary excellent competences to introduce beyond cuttingedge integrated sensor technology widely in production and products of Swedish industry. This allows a new level of adaptive control, use of AI integration in production, exact management of material and energy resources, introduction of new production methods, extending product lifetimes and a bre
