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Gastroparesis is a well-known complication of diabetes mellitus, both in symptomatic and asymptomatic patients. Esophageal dysmotility has also been described, but is not as well-characterized. The etiology and effect of these complications need to be clarified. The aim of the present study was to evaluate esophageal and gastric motility, complications, gastrointestinal symptoms, and plasma biomar
Objectives: Depression is common but not always recognized and often undertreated among elderly. Cardiovascular diagnoses have been reported to be associated with depression. The study examined if this association could be confirmed in a frail elderly population. It also assessed the association between high depressive scores and certain health complaints and the use of certain drugs, respectively
Popular Abstract in Swedish Under de senaste par decennierna har en specifik tolkning av döva och dövhet blivit alltmer etablerad på det ”officiella” dövområdet i Sverige, tillika anammat av såväl professionella som föräldrar till döva barn. Döva ska enligt detta synsätt hellre betraktas som tillhörande en kulturell och språklig minoritet än som handikappade. Medicinska strävanden att “laga defektIn the last couple of decades a particular interpretation of deaf and deafness has been established in ‘official’ arenas in Sweden. Deaf individuals, according to this view, should not be seen as disabled, but rather as belonging to a cultural and linguistic minority. Such views find expression in a locally established usage that may be termed a deaf culture discourse. Discourse can be seen as a
AimsTo assess the variation in ovarian carcinoma type diagnosis among gynaecological pathologists from Nordic countries, and whether a rationally designed panel of immunohistochemical markers could improve diagnostic reproducibility. Methods and resultsEight pathologists from four countries (Sweden, Denmark, Norway, and Finland) received an educational lecture on the diagnosis of ovarian carcinoma
There is a need for improvement of the commonly used adenovirus vectors based on serotype 5. This study was performed on three adenovirus serotypes with a CAR-binding motif (Ad4p, Ad5p and Ad17p) and three non-CAR-binding serotypes (Ad11p, Ad16p and Ad21p). The capacity of these alternative adenovirus vector candidates to deliver DNA into low-passage glioma cell lines from seven different donors w
Policy on greening freight constitutes a recent addition to the discourse on sustainability in the EU. To stimulate economic growth, the EU also plans for freight transport activity to grow significantly over the coming decades. In this paper, drawing on critical discourse analysis and Marxian geographical thought, I show how the argument for implementing sustainable freight is constructed in EU f
We investigated the function of cyclin-dependent kinase 2 (Cdk2) in neural progenitor cells during postnatal development. Chondroitin sulfate proteoglycan (NG2)-expressing progenitor cells of the subventricular zone (SVZ) show no significant difference in density and proliferation between Cdk2-/- and wild-type mice at perinatal ages and are reduced only in adult Cdk2 -/- mice. Adult Cdk2-/- SVZ ce
Mörk materia har funnits sedan tidernas begynnelse, från den Stora Smällen. Under Universums första hundratals miljoner år var tyngdkraften från den mörka materian så kraftfull att den drog till sig den vanliga materian, som muskler till revben, och formade gigantiska strukturer. De första galaxerna växte där dessa strängar möttes.Galaxer kolliderade med andra galaxer, och slogs samman för att
The biochemical mechanisms underlying glucose-stimulated insulin secretion from pancreatic beta-cells are not completely understood. To identify metabolic disturbances in beta-cells that impair glucose-stimulated insulin secretion, we compared two INS-1-derived clonal beta-cell lines, which are glucose-responsive (832/13) or glucose-unresponsive (832/2). We found that despite a marked impairment o
Abstract Background. The plasma level of cystatin C is a better marker than plasma creatinine for successful aging. It has been assumed that the advantage of cystatin C is not only due to it being a better marker for glomerular filtration rate (GFR) than creatinine, but also because an inflammatory state of a patient induces a raised cystatin C level. However, the observations of an association be
