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Background: The aim of this study was to describe out-of-hospital cardiac arrest (OHCA) survivors' ability to participate in activities of everyday life and society, including return to work. The specific aim was to evaluate potential effects of cognitive impairment. Methods and Results: Two hundred eighty-seven OHCA survivors included in the TTM trial (Target Temperature Management) and 119 match
In recent years, the need for sustainable practices within the food industry has become increasingly important and incorporating Industry 4 [...]
In order to alleviate the financial burden on the healthcare sector as well as relax its employees’ workload, there is a need to introduce novel tools that automate some of the tasks that today are performed manually. Especially pathology poses a problem with few pathologists, demanding manual labour and unnecessary work on benign tissue. As a response, the DOGS project aims to develop a tool to a
The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple
The zinc finger transcription factor Wilms' tumor gene 1 (WT1) acts as an oncogene in acute myeloid leukemia. A naturally occurring alternative splice event between zinc fingers three and four, removing or retaining three amino acids (+/-KTS), is believed to change the DNA binding affinity of WT1, although there are conflicting data regarding the binding affinity and motifs of the different isofor
Photodynamic therapy (PDT) for the treatment of prostate cancer has been demonstrated to be a safe treatment option capable of inducing tissue necrosis and decrease in prostate specific antigen (PSA). Research groups report on large variations in treatment response, possibly due to biological variations in tissue composition and shortterm response to the therapeutic irradiation. Within our group,
Recent animal studies have shown that D-glucose is a potential biodegradable MRI contrast agent for imaging glucose uptake in tumors. Here, we show the first translation of that use of D-glucose to human studies. Chemical exchange saturation transfer (CEST) MRI at a single frequency offset optimized for detection of hydroxyl protons in D-glucose (glucoCEST) was used to image dynamic signal changes
Popular Abstract in Swedish Den här boken handlar om ömsesidighet i sociala relationer - om vänskap. Den handlar också om de moraliska och rättsliga normer och föreställningar som istället främjar ensidiga, eller till och med direkt fientliga, relationer. Arbetet utgår från vissa centrala punkter i den aristoteliska etiken. Undersökningen kretsar kring de värden som konstituerar den sociala relatiThis is a book about reciprocity in social relationships - about friendship. It also deals with the moral and legal norms which, conversely, promote one-sided and even directly hostile relationships. The starting-point for this work is certain central elements in Aristotelian ethics. The study revolves around the values which constitute the social relationship of friendship and the central questio
Aim: “Early” withdrawal of life support therapies (eWLST) within the first 3 calendar days after resuscitation from cardiac arrest (CA) is discouraged. We evaluated a prospective multicenter registry of patients admitted to hospitals after resuscitation from CA to determine predictors of eWLST and estimate its impact on outcomes. Methods: CA survivors enrolled from 2012–2017 in the International C
Purpose: The emphasis on early diagnosis to improve cancer survival has been a key factor in the development of cancer pathways across Europe. The aim of this analysis was to explore how the emphasis on early diagnosis and timely treatment is reflected in patient's accounts of care, from the first suspicion of colorectal or lung cancer to their treatment in Denmark, England and Sweden. Method: We
The Paris Agreement requests a substantial reduction of greenhouse gas (GHG) emissions. These emissions are currently mainly estimated from bottom-up inventories and process-based models of land and ocean fluxes. Another, complementary approach is based on measurements of the atmospheric GHG concentration in combination with atmospheric inverse modelling to provide the GHG fluxes. For the latter a
The sharing of digital information between phases in the planning and building process still have shortcomings. Ourstudy is performed as a test case on a construction project in a municipality and focuses on two aspects of how the sharing of building information could be improved: 1) to get a more process oriented approach to the information flow. Here we will test if the ISO-standard Product Life
Reliable safe water supply is a pillar of society and a key to public health. The Nordic countries have an abundance of clean fresh water as a source for drinking water supplies. They have followed developments in safeguarding water, both the recommendations of the World Health Organization framework for safe drinking water and European legislation. Worldwide, including the Nordic countries, small
Purpose: Onyx® embolization causes severe artifacts on subsequent CT-examinations, thereby seriously limiting the diagnostic quality. The purpose of this work was to compare the diagnostic quality of the tailored metal artifact reducing algorithms iMAR to standard reconstructions of CTA in patients treated with Onyx® embolization. Method: Twelve consecutive patients examined with Dual Energy CTA a
Purpose: Neurofilament light (NfL) is a biomarker reflecting neurodegeneration and acute neuronal injury, and an increase is found following hypoxic brain damage. We assessed the ability of plasma NfL to predict outcome in comatose patients after out-of-hospital cardiac arrest (OHCA). We also compared plasma NfL concentrations between patients treated with two different targets of arterial carbon
A massive population growth in cities is currently being witnessed in most countries around the world. As urban populations grow, cities eventually expand geographically into what was considered countryside and nowadays distinguishing between what is city and what is countryside is getting increasingly difficult. In many Western countries, it is being observed that areas near cities seem to capita
Objectives: Dysglycemia and glycemic variability are associated with poor outcomes in critically ill patients. Targeted temperature management alters blood glucose homeostasis. We investigated the association between blood glucose concentrations and glycemic variability and the neurologic outcomes of patients randomized to targeted temperature management at 33°C or 36°C after cardiac arrest. Desig
