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167 MP279 You Et Al. Joint Modeling AOAS 2024

Joint modeling of multistate and nonparametric multivariate longitudinal data The Annals of Applied Statistics 2024, Vol. 18, No. 3, 2444–2461 https://doi.org/10.1214/24-AOAS1889 © Institute of Mathematical Statistics, 2024 JOINT MODELING OF MULTISTATE AND NONPARAMETRIC MULTIVARIATE LONGITUDINAL DATA BY LU YOU1,a, FALASTIN SALAMI2,c, CARINA TÖRN2,d, ÅKE LERNMARK2,e AND ROY TAMURA1,b 1Health Inform

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-01/167_MP279_You%20et%20al.%20%20Joint%20modeling%20_AOAS_2024.pdf - 2026-05-26

Formation of the bicoid morphogen gradient: an mRNA gradient dictates the protein gradient

The Bicoid (Bcd) protein gradient is generally believed to be established in pre-blastoderm Drosophila embryos by the diffusion of Bcd protein after translation of maternal mRNA, which serves as a strictly localized source of Bcd at the anterior pole. However, we previously published evidence that the Bcd gradient is preceded by a bcd mRNA gradient. Here, we have revisited and extended this observ

Telomerase activation as a possible mechanism of action for psychopharmacological interventions.

Originally studied in relation to aging and cancer research, telomerase is now also investigated in relation to psychiatric disorders and treatments. Based on emerging clinical and preclinical data, we hypothesise that telomerase activation could represent a novel element mediating the mechanism of action of certain psychopharmacological interventions (e.g. antidepressants, lithium and antipsychot

Protein microchip bioassay with dual fluorescent- and MALDI read-out.

Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundan

Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: Six-month study

Several studies have shown that alpha-ketoglutaric acid (AKG) increases serum levels of proline and has beneficial effects on skeletal development. We studied the effect of alpha-ketoglutaric (AKG) acid calcium salt (6 g AKG and 1,68 Ca/day) or calcium alone (1.68 Ca/day) on serum C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin (OC), as well as lumbar spine bone minera

Dykungens dotter : hos H. C. Andersen och Birgitta Trotzig

Hans Christian Andersen's tale "The Marsh King's Daughter" (1858) is analysed in relation to Birgitta Trotzig's prose tale of the same title, Dykungens dotter (1985), with the emphasis on Andersen's tale which would seem to be a pious Christian morality in which evil is destroyed and the powers of light conquer darkness. At the same time, Andersen's symbols make clear that darkness is a necessary

BRCA1-positive patients are small for gestational age compared with their unaffected relatives

The BRCA1 gene is thought to exert its main function early in life. We, therefore, studied the effects of BRCA1 mutations on birth weight and birth length. This was carried out by comparing 33 women with and without mutations. Birth weight and length were obtained from a self-administered questionnaire. BRCA1 mutations carriers had a significantly lower birth weight (P = 0.0041) compared with non-

How to compensate the irreplaceable? A socio-legal research project within victimology about the relation between formal and informal norms

As an ambition to stress the construction of an external and an internal dimension within law I have chosen to study the non-pecuniary damages to victims of crime. The foundation for these damages came from the deep structure of law about the idea that the right to integrity of the human body and soul are one of the corner- stones in the state governed by law. But when it comes to estimating the a

Kontinuerliga tvåfraktionsinsamlare för övervakning av partikulära luftföroreningar i arbetsmiljö

Rapporten beskriver prototyper av kontinuerliga tvåfraktionsinsamlare för övervakning av partikulära luftföroreningar i arbetsmiljö som har konstruerats. En prototyp är personburen och ger möjligheter till insamling av två partikelstorleksfraktioner i 18 diskreta intervall. PIXE-metoden (analys med partikelinducerad röntgenstrålning) används för multielementanalys av de erhållna proven. Även med m