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Diffusion-weighted magnetic resonance imaging (DW-MRI) aims to disentangle multiple biological signal sources in each imaging voxel, enabling the computation of innovative maps of tissue microstructure. DW-MRI model development has been dominated by brain applications. More recently, advanced methods with high fidelity to histology are gaining momentum in other contexts, for example, in oncologica
We present the first systematic comparison of the charged-particle pseudorapidity densities for three widely different collision systems, pp, p–Pb, and Pb–Pb, at the top energy of the Large Hadron Collider (sNN=5.02TeV) measured over a wide pseudorapidity range (−3.5
BACKGROUND: Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with Type 2 diabetes (T2D).METHODS: We conducted a systematic review and meta-analysis of longitudinal studies to identify potentially novel prognostic factors that may improve CVD risk prediction in T2D. Out of 9380 studies identified, 416 studies met inclusion criteria. Outcome
INTRODUCTION: Hip and knee osteoarthritis (OA) are increasingly common with a significant impact on individuals and society. Non-pharmacological treatments are considered essential to reduce pain and improve function and quality of life. EULAR recommendations for the non-pharmacological core management of hip and knee OA were published in 2013. Given the large number of subsequent studies, an upda
The bonding of glass substrates is an important process in the fabrication of glass micro/nanofluidic devices. In this study, the influence of the surface roughness of glass substrates after low-temperature bonding is investigated. It is found that plasma etching can be used to control the surface roughness to the range 2-9 nm. Substrates with a roughness of 5 nm or less can be bonded. The pressur
Responsible internationalization is a term increasingly used to promote relationship building in a world shaped by the growing impact of global challenges and geopolitical competition. In these changing global conditions, researchers and universities have learned that they need to adhere to an expanded set of research norms. Today these norms include aspects well known to researchers, such as rese
A fundamental issue in the metabolic field is whether it is possible to understand underlying mechanisms that characterize individual variation. Whole-animal performance relies on mitochondrial function as it produces energy for cellular processes. However, our lack of longitudinal measures to evaluate how mitochondrial function can change within and among individuals and with environmental contex
Leveraging the potential of machine learning and recognizing the broad applications of binary classification, it becomes essential to develop platforms that are not only powerful but also transparent, interpretable, and user friendly. We introduce alphaML, a user-friendly platform that provides clear, legible, explainable, transparent, and elucidative (CLETE) binary classification models with comp
Asthma, which affects some 300 million people worldwide and caused 455,000 deaths in 2019, is a significant burden to suffers and to society. It is the most common chronic disease in children and represents one of the major causes for years lived with disability. Significant efforts are made by organizations such as WHO in improving the diagnosis, treatment and monitoring of asthma. However asthma
OBJECTIVE: The longitudinal variations in serum levels of the hormone osteocalcin is largely unknown during infancy and early childhood. Our aim was to establish reference limits for total serum osteocalcin during specific time points from birth until 5 years of age and present those in the context of sex, breastfeeding practices and gestational age (GA).DESIGN: Blood samples from 551 Swedish chil
The increasingtest data volume required to ensure high test quality when testinga System-on-Chip is becoming a problem since it (the test datavolume) must fit the ATE (Automatic Test Equipment) memory. In thispaper, we (1) define a test quality metric based on fault coverage,defect probability and number of applied test vectors, and (2) atest data truncation scheme. The truncation scheme combines
The dynamics of ethanol production/consumption in baker's yeast were studied under feed- rate controlled conditions. The yeast was grown on molasses in an 8-l fed-batch reactor and experiments were done at cell concentrations between 5 and 65 g l−1. Small changes in the feed rate were made around a feed rate corresponding to the critical growth rate, at which the yeast cell metabolism switches bet
Objective: Varying degrees of inter-organizational collaboration concerning children at risk has grown rapidly since the 1980s. Collaboration is understood to provide a more holistic view of the child’s needs, lead to better care and treatment, more efficient law enforcement as well as increase knowledge in general. The aim of this presentation is to explore processes and effects, by highlighting
Using a system analysis approach compares different systems for handling and treatment of toilet waste and organic household waste. Design issues considered are source separation of urine, use of vacuum toilets and advanced nutrient recovery processes such as Reverse Osmosis (RO). All of the studied systems have low emissions of eutrophy ing compounds. Other environmental effects are mainly relate
