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The present work is mainly focused on the development of enzyme-based bioanalytical devices, which can further be applied as analytical tools for industrial, medical and environmental applications. The first part of the work deals with the practical applications of thermometric biosensors for determination of various sugars (fructose and lactose) in a real samples. Thermometric biosensors possess
Water vapor condensation and two-phase flow appear in plate heat exchangers being used as condensers. Analysis of water phase change and flow dynamics is an important but complicated task due to large change in water physical/transport properties across the water liquid-vapor interface boundary. In particular, a singular-link behaviour in Navier-Stokes (N-S) equations is present due to the large s
Participatory design (PD) has taken as its ideal that designers and users should engage in an equal language game. When we apply PD in contexts where some of the users involved are weak, ill, or have impairments, this assumed equality can no longer be an ideal. The workshop explores new ideals for participatory design in non-work settings with highly heterogeneous user constellations.
Corporate mergers and acquisitions (M&As) have during the last decade established themselves as prominent tools for corporate strategy. Consequently, more and more organizations direct their attention towards the potential benefits of a corporate merger and acquisition (M&A) and the problems of leveraging the potentials. This thesis addresses information systems (IS) integration in the con
The thesis aims to compare two approaches to psychosocial rehabilitation – day centres and clubhouses – and to explore if either appears better suited to support people in mental health recovery. The recovery focus is on opportunities for engaging in meaningful daily occupations, accessibility to social interaction and factors pertaining to perceived health and well-being. The thesis consists of f
The aim of this study was to investigate non-solvent precipitation of starch to produce nanoparticles that could be used in Pickering emulsions. The material used was waxy maize, modified with octenyl succinic anhydride. Different methods of non-solvent precipitation were investigated, and a method based on direct mixing of an 8% starch solution and ethanol (ratio 1:1) was found to produce the sma
Quantum chemical geometry optimisations have been performed on realistic models of the active site of myoglobin using density functional methods. The energy of the hydrogen bond between the distal histidine residue and CO or O2 has been estimated to be 8 kJ/mol and 32 kJ/mol, respectively. This 24 k J/mol energy difference accounts for most of the discrimination between CO and O2 by myoglobin (abo
Water exchange of tetraaquaplatinum(II) has been studies by use of high-pressure oxygen-17 NMR spectroscopy. Negative entropies and negative volumes of activation support associative activation. The tretraaquapalladium(II) complex reacts 1.4x10exp6 times faster than the corresponding platinum(II) complex.
Background: Chronic non-healing wounds present a substantial economic burden to healthcare system; significant reductions in quality of life for those affected, and precede often serious events such as limp amputations or even premature deaths. This burden is also likely to increase with a larger proportion of elderly and increasing prevalence of life-style diseases such as obesity and diabetes. R
Cerebrospinal fluid (CSF) biomarkers may support the diagnosis of Alzheimer's disease (AD). We studied if the diagnostic power of AD CSF biomarker concentrations, i.e., Aβ42, total tau (t-tau), and phosphorylated tau (p-tau), is affected by differences in lateral ventricular volume (VV), using CSF biomarker data and magnetic resonance imaging (MRI) scans of 730 subjects, from 13 European Memory Cl
Global warming and its effects on climate are of great concern. Climate change can affect buildings in different ways. Increased structural loads from wind and water, changes in energy need and decreased moisture durability of materials are some examples of the consequences. Future climate conditions are simulated by global climate models (GCMs). Downscaling by regional climate models (RCMs) provi
