Filetype
INTRODUCTION: Development of asthma and allergies in childhood/adolescence commonly follows a sequential progression termed the 'atopic march'. Recent reports indicate, however, that these diseases are composed of multiple distinct phenotypes, with possibly differential trajectories. We aim to synthesise the current literature in the field of machine learning-based trajectory studies of asthma/all
The diagnosis of lymphoma relies mainly on clinical examination and laboratory explorations. Among the latter, morphological and immunohistochemical analysis of a tissue biopsy are the cornerstones for proper identification and classification of the disease. In lymphoma with blood and/or bone marrow involvement, multiparameter flow cytometry is useful. This technique can also be applied to fresh c
The acidobasic and complexing properties of 1-methyl-2-mercaptoimidazole (Methimazole, an anti-thyroid drug) were investigated. The pKa 11.49 ± 0.03 was estimated by molecular absorption spectroscopy (I = 0.10 M NaCl, t = 25.0 ± 0.1 °C). This value is in good agreement with the value 11.58 ± 0.05, obtained using the solvent-extraction technique. Theoretical (LFER and quantum chemical calculations)
Oncologists frequently approach patients to discuss difficult topics, such as bad news about cancer progression and referrals to palliative care and hospice. To communicate effectively in these difficult situations, it is helpful to assess what the patient knows and wants to know about their disease in general and, specifically, their prognosis. Although some patients fully accept the diagnosis of
Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxy
Over recent decades, management of people with hemophilia (PwH) has been greatly improved by scientific advances that have resulted in a rich and varied therapeutic landscape. Nevertheless, treatment limitations continue to drive innovation, and emerging options have the potential to realize further improvement. We advocate four general principles to optimize benefits from innovation: individualiz
The Swedish Campaign for Nuclear Disarmament (SCND) fought the military’s plans to acquire Swedish nuclear weapons and protested the nuclear arms race, 1961–1967. This article presents SCND’s ideological orientation by focusing on temporalities. SCND saw the Second World War as a decisive event and tried to avert a crisis and a dystopia by manifesting remembrance of past nuclear detonations, and b
OBJECTIVES: Analysis of the long-term risks of ischaemic stroke and cerebral bleeding in patients with atrial fibrillation after mitral valve surgery and concomitant Cox-maze IV procedure. METHODS: In total, 397 patients with symptomatic degenerative mitral valve insuffciency and atrial fibrillation, underwent mitral valve surgery and Cox-maze IV in Sweden between 2009 and 2017. In this retrospect
Glucuronic acid (GlcA) is an abundant substituent in hardwood xylan, and it is often found in its methylated form as methyl glucuronic acid (MeGlcA). GlcA and MeGlcA are sugar acids, bound to the xylose backbone at position O-2, and their presence can affect the digestibility of the polymer. Currently, detection of released GlcA or MeGlcA from synthetic substrates such as pNP-glucuronic acid can b
Pathways to Sustainable Welfare critically examines how cities can address the dual challenges of climate change and sustainability while ensuring the welfare of their populations.Focused on three Swedish cities, it explores the integration of environmental and welfare concerns in local policies, urban movements and public opinions. Based on theories of inertia, emergence and transformation, it id
The higher education sector has been massively disrupted by COVID-19. The technological changes of the past two decades have enabled a ‘blended learning’ approach. Nonetheless, most academics were not prepared to become fully online teachers with very short notice (nor were most students prepared to learn online) in 2020. Our aim was to investigate and document changes in teaching from the perspec
Our understanding of public support for climate policies predominantly stems from studies in the Global North and a focus on isolated policy types. Here, we examine how public support for four different climate policy types and the effect of ideological explanatory variables on such support vary among countries of the Global North and Global South. We surveyed representative samples of each three
Internet of Things (IoT) are one of the key enablers of personalized health. However, IoT devices often have stringent constraints in terms of resources, e.g., energy budget, and, therefore, limited possibilities to exploit the state-of-the-art Deep Neural Networks (DNNs). Energy-aware Neural Architecture Search (NAS) is proposed to tackle this challenge, by exploring lightweight DNN (DNN) archite
Lidar technology was utilized to non-destructively explore the diverse insect life in the Taï virgin forest of Côte d'Ivoire. This study employed an entomological Lidar scanned at different elevation angles, combined with traditional insect trapping at different canopy heights, to investigate the composition and spatial-temporal distribution of insects within the forest canopy. We detected stratif
Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake. Here, we evaluated the efficacy and safety of combined administration of two dopamine-enhancing drugs, varenicline (a partial nicotinic acetylcholine receptor
Context. HR 10 has only recently been identified as a binary system. Previously thought to be an A-type shell star, it appears that both components are fast-rotating A-type stars, each presenting a circumstellar envelope. Although showing complex photometric variability, spectroscopic observations of the metallic absorption lines reveal variation explained by the binarity, but not indicative of de
Wood's flammability, low dimensional stability, and poor fungal resistance limit its application. In this study, Scots pine sapwood (Pinus sylvestris L.) was treated with a low-molecular-weight phenol–formaldehyde (PF) resin and a monoguanidine phosphate flame retardant (FR) to achieve multifunctional enhancement. Differential scanning calorimetry confirmed no interference of FR with PF curing, wh
This work advances and demonstrates the utility of a reporting framework for collecting and evaluating annotations of medical images used for training and testing artificial intelligence (AI) models in assisting detection and diagnosis. AI has unique reporting requirements, as shown by the AI extensions to the CONSORT (Consolidated Standards of Reporting Trials) and SPIRIT (Standard Protocol Items
