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Background and purpose - Assessment of potential disparities in access to care is a vital part of achieving equity in health and healthcare. We have therefore studied the effect of socioeconomic status (SES) on the rates of knee and hip replacement due to osteoarthritis. Methods - This was a cohort study in Skåne, Sweden. We included all residents aged ≥ 35 years with consultations between 2004 an

A reliable serological marker of acute cellular rejection (ACR) after small bowel transplantation (SBTx) is still missing. Plasma citrulline level (PCL) reflects the functional integrity of intestinal mucosa which is partially lost during ACR. The aim of our study was to investigate the role of PCL as marker of ACR after SBTx. Eighteen German landrace pigs were used and divided into three groups.

Importance: Circulating levels of neurofilament light (NfL) and glial fibrillary acidic protein (GFAP) are important in the course of brain injury in adults, but longitudinal postnatal circulating levels in preterm infants have not been investigated. Objectives: To examine postnatal longitudinal serum levels of NfL and GFAP in preterm infants during the first 15 weeks of life and to explore possib

The last couple of decades have seen an explosion of novel colloidal drug delivery systems, which have been demonstrated to increase drug efficacy, reduce side-effects, and provide various other advantages for both small-molecule and biomacromolecular drugs. The interactions of delivery systems with biomembranes are increasingly recognized to play a key role for efficient eradication of pathogens

Introducing a sociological perspective on judicial emotions, we argue that previous studies underemphasize structural andinteractional dimensions. Through key concepts in the sociology of emotions we relate professional court actors’ emotionmanagement to the emotional regime of the judiciary. Examples from the Swedish judiciary illustrate three main arguments:(a) The idea of rational justice as noIntroducing a sociological perspective on judicial emotions, we argue that previous studies underemphasize structural andinteractional dimensions. Through key concepts in the sociology of emotions we relate professional court actors’ emotionmanagement to the emotional regime of the judiciary. Examples from the Swedish judiciary illustrate three main arguments:(a) The idea of rational justice as no

Background: OncoMasTR is a new multigene prognostic test that was discovered via a novel transcriptional network analysis method that identified upstream Master Transcription Regulators (MTRs), which regulate previously identified prognostic biomarkers. The optimised OncoMasTR signature incorporating clinicopathological information has been shown to be significantly prognostic for predicting dista

The understanding of the genesis of life-threatening cancer and its invasion calls for urgent development of novel technologies for real-time observations, early diagnosis, and treatment. Quantum dots (QDs) grabbed the spotlight in oncology owing to their excellent photostability, bright fluorescence, high biocompatibility, good electrical and chemical stability with minimum invasiveness. Recently

Huntington's disease (HD) is caused by an expanded polyglutamine tract in the protein huntingtin (htt). Although HD has historically been viewed as a brain-specific disease, htt is expressed ubiquitously, and recent studies indicate that mutant htt might cause changes to the immune system that could contribute to pathogenesis. Monocytes from HD patients and mouse models are hyperactive in response

The invention relates to hyperpolarised 13C-alanine, its use as imaging agent, an imaging medium comprising hyperpolarised 13C-alanine and methods of 13C-MR detection wherein such an imaging medium is used. Further, the invention relates to methods of producing hyperpolarised 13C-alanine.

Many neurons typically fire action potentials in brief, high-frequency bursts with specific consequences for their synaptic output. Here we have examined short-term plasticity engaged during burst activation using electrophysiological recordings in acute rat hippocampal slices. We show that CA3-CA1 glutamate synapses exhibit a prominent depression of presynaptic release probability for approximate

Omkring 20 procent av alla människor världen över (1,5 miljarder) har inte ett officiellt, juridiskt dokument som bevis på sin identitet. Detta påverkar till exempel deras rösträtt, att öppna ett bankkonto, få formell anställning eller söka juridisk ersättning. Deras brist på bevis på juridisk existens exkluderar dem alltså från att delta på samtliga nivåer i samhället. Denna omfattande problematiAround 20% of all people worldwide (1.5 billion) do not have an official and legally recognized document as proof of their identity. This affect, for example, their right to vote, to open a bank account, obtain formal employment or seek legal compensation. In other words, their lack of proof for their legal existence excludes them from participating in society on all various levels. This was ackno

Detta examensarbete ger ett förslag på en ny järnvägsstation i Kirunas nya centrum. I Kiruna pågår just nu en stadsomvandling, där en tredjedel av staden flyttas tre kilometer österut på grund av markdeformationer från Kirunagruvan. Detta innebär stora förändringar för Kirunaborna men även stora förändringar i stadsbilden, då majoriteten av centrum har eller kommer rivas och byggas upp igen i nya This thesis gives a suggestion for a new railway station in the new city center of Kiruna, Sweden. Kiruna is now experiencing an urban transformation, where one third of the population and the city moves three kilometers to the east due to ground deformations coming from the Kiruna iron ore mine. This leads to huge changes for Kiruna’s population, but also huge changes in the cityscape, since most

The airline industry is undergoing hard time after the deregulation. Incumbents are facing increased competition from the new entrants- low cost airlines and try to keep their market share, which is mainly composed of business travelers to themselves. At the same time low cost airlines by providing low cost, point-to-point services try to compete with incumbents. Strategies of both incumbent and l

Agriculture Development Led Industrialization (ADLI) has been government development strategy since 1990s; and its objective was to develop a market oriented modernized agriculture sector, with the development of the industry to follow this as a next development stage using the raw material from agriculture. The strategies for the agriculture development have focussed on extension and research ser

Eutektiska lösningar är en blandning av två fasta ämnen som bildar en vätska i rumstemperatur när de blandas i rätt förhållande. Det som sker är att molekylerna i de två ämnena binder starkt till varandra och bygger upp ett nätverk mellan sig och på så sätt bildar en vätska. Läkemedel innehåller en aktiv substans, det som faktiskt hjälper när man har ont eller är sjuk. Många aktiva substanser trivDeep eutectic solvents, DES, is a type of solvent made by mixing a quaternary ammonium salt with a hydrogen bond donor at the eutectic point of the system. Most common quaternary ammonium salt is Choline Chloride, ChCl. A specific DES, Choline:CAGE has shown promise in delivering insulin through the skin of mice. Four different systems containing Choline chloride were chosen: ChCl:glycerol, ChCl:

När en kvinna föder barn kan hon få skador i underlivet. Det kan göra att man senare behöver opereras för att t.ex. tarmen eller urinblåsan inte sitter helt fast på sin ursprungliga plats i magen utan istället buktar ut i slidan, något som kallas för framfall. Ca 7000 kvinnor opereras för sådana problem varje år i Sverige och det blir en stor kostnad för samhället. Även om man kan få framfall utanBACKGROUND: It is well-known that pelvic organ prolapses and perineal tears can be a consequence of vaginal birth. Seven thousand women undergo surgery for pelvic organ prolapses in Sweden every year. OBJECTIVE: To search for medical literature that describes the identification and repair of the anatomical structures present in obstetrical perineal tears. To make an attempt to understand how prola

Problem discussion: The internal foundry of ITT Flygt occasionally has problems with on-time delivery to the product workshops. This could lead to extra costs regarding labour and stock keeping. ITT Flygt are today unaware of the extent of these costs. Objectives: The main objective of the master thesis is to investigate the effects of low delivery accuracy from the foundry to PVC. This main objec

Low-energy buildings are nowadays often used in common speech, for selling or promotion – everything has to be ”low energy”. But how do you know if your house is a low energy building? And how do the manufacturers of the building components know? Is there an official definition, what technical criteria do these buildings have to fulfill? The growing of low-energy buildings causes a demand of compl