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Hyperinsulinemia is an adaptive mechanism that enables the maintenance of normoglycemia in the presence of insulin resistance. We assessed whether glucagon is also involved in the adaptation to insulin resistance. A total of 1,437 individuals underwent an oral glucose tolerance test with measurements of circulating glucose, insulin, and glucagon concentrations at 0, 30 and 120 min. Early glucagon
Multilevel Monte Carlo is a novel method for reducing the computational cost when computing conditional expectations of stochastic processes. This paper considers the transition density for diffusion processes. It is known that the transition density can be written as an expectation by utilizing the law of total probability combined with the Markov property. This idea is combined with the multilev
Background: Although sugar consumption has been associated with several risk factors for cardiometabolic diseases, evidence for harmful long-term effects is lacking. In addition, most studies have focused on sugar-sweetened beverages (SSBs), not sugar per se. Objective: The aim of this study was to examine the associations between added and free sugar intake, intake of different sugar sources, a
Heterotrimeric G proteins are intracellular membrane-attached signal transducers involved in various cellular processes in both plants and animals. They consist of three subunits denoted as α, β and γ. The γ-subunits of the so-called AGG3 type, which comprise a transmembrane domain, are exclusively found in plants. In model species, these proteins have been shown to participate in the control of p
Background: The W allele of the G460W polymorphism in the adducin-1 gene has been occasionally associated with increased blood pressure (BP). The aim of this study was to test whether the G460W variant is associated with BP levels and BP progression rate and whether G460W associations with BP are affected by sex, body mass index (BMI), or age. Methods: The G460W polymorphism was genotyped in the p
A delayed rectifier voltage-gated K+ channel (Kv) represents the largest ionic conductance of platelets and megakaryocytes, but is undefined at the molecular level. Quantitative RT-PCR of all known Kv alpha and ancillary subunits showed that only Kv1.3 (KCNA3) is substantially expressed in human platelets. Furthermore, megakaryocytes from Kv1.3-/- mice or from wild-type mice exposed to the Kv1.3 b
The purpose of this thesis is to discuss the reasoning behind the prominence of resilience building in Malawi’s development strategies, how resilience building is performed in Malawi, and what the potential and consequences of resilience in Malawi might be. In observations of a resilience building project and interviews with development practitioners, it was found that resilience had become promin
Vi har i detta examensarbete utfört samtidig mätning av värmeutveckling (hydratationshastigheten) och relativ fuktighet (självuttorkningen) hos hydratiserande cement. Denna studie har gjorts på fyra grundrecept med olika cement där vatteninnehållet har varierats för att få olika självuttorkning. Mätningarna av relativ fuktighet är utförda med RF-sensorer som ger utslag i millivolt som därefter omv
Human Rights questions has during the last 60 years been one of the biggest questions among which people come together to support each other. It was the responsibility of states to make sure that no violations of the UDHR made by other states, individuals or companies were possible, but no solid rules have been created. During the last couple of years multi-national enterprises has gathered in a p
The Old Wood in a New Light database project focuses on the digitization and accessibility of the results of dendrochronological samples analyzed and archived at four Swedish university-based tree-ring laboratories at Lund University, Stockholm University, University of Gothenburg, and the Swedish University of Agricultural Sciences. Collaboration with the Environmental Archaeology Laboratory and The Old Wood in a New Light database project focuses on the digitization and accessibility of the results of dendrochronological samples analyzed and archived at four Swedish university-based tree-ring laboratories at Lund University, Stockholm University, University of Gothenburg, and the Swedish University of Agricultural Sciences. Collaboration with the Environmental Archaeology Laboratory and
Backgrounds: There is a discrepancy between west and east on the relationship between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). This study aimed to find out the possible reason for this and to clarify the association between NAFLD and CKD by analyzing two population-based datasets from the US and China. Methods: Two health examination datasets from China and the U
In this study we use comparative genomics to uncover a gene with uncharacterized function (1700011H14Rik/C14orf105/CCDC198), which we hereby name FAME (Factor Associated with Metabolism and Energy). We observe that FAME shows an unusually high evolutionary divergence in birds and mammals. Through the comparison of single nucleotide polymorphisms, we identify gene flow of FAME from Neandertals into
Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer. In the present study, we examined the expression of cystatin C and its association with matrix metalloproteinases 2 (MMP2) and androgen receptor (AR) in a tissue microarray compa
This paper examines how the International laws of, in and after war are, as a Schmittian political theology, instructed by a Christian eschatological concept of time. The paper uncovers how Christian remnants are present in both international law and in our Nordic societies, suggesting that we ought to consider carefully how our understanding and narration of time is furthering the eschatological
Transfer pricing and EU customs law are regulated by two separate sets of rules. Ultimately, the objective of transfer pricing, as a tax measure, is to ensure that the transactions between associated enterprises are conducted in accordance with the same terms as between independent enterprises. The objective of EU customs law is, however, to ensure that the single market of the EU functions proper
Meddelanden från HT-biblioteken | oktober 2025 Meddelanden från HT-biblioteken | oktober 2025 Publicerad den 15 oktober 2025 https://www.pickpik.com Här kommer oktober månads nyhetsbrev från HT-biblioteken. Det innehåller bland annat information om våra workshops, dokumenthanteringsplanen Klara Dialog, vårt nyförvärv och månadens e-resurs L'Année philologique. Innehållsförteckning Finn – nytt söks
https://www.htbibl.lu.se/article/meddelanden-fraan-ht-biblioteken-oktober-2025 - 2026-07-02
