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Development of a concept for a SmartCashCenter

A trend, which can be noted in the field of cash handling, is the increase of ATMs that are able to recirculate banknotes. Cash recycling means that notes deposited by one customer are then available for withdrawal by another from the same machine. Cash recycling has both economic advantages and reduces environment impact, as transport to machines for filling and emptying them can be decreased. Wh

Structure and energetics of molecular recognition in galectin-3-ligand interactions

Molecular recognition is the key aspect of any cellular and biological function. Two or more molecules interacting with each other cause the effects that drives various basic functions that are fundamental to cells. Be these protein-protein, protein-nucleic acid or protein-ligand interactions, they all play important roles in a cell. Protein-ligand interactions are the most studied as they can hav

Assessment of Computational Methods for Ligand Binding

Most drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca

Purchasing Assessment Tool – Assessment and benchmarking of strategic purchaser skill set

The role of strategic purchasing has become increasingly important for financial success, and the portfolio of necessary skills and competencies has evolved. However, ways of assessing current competency levels for strategic purchasing development are not standardized, objective or efficient. In our thesis, we created and validated a Multiple Choice Question assessment tool for this purpo

A polynomial multicommodity flow problem with difficult path generation

In the paper we consider a commonly known network design problem with demand restoration assuming stub release. No compact linear programming (LP) formulation for the problem is known, and all known non-compact LP formulations of the problem require NP-hard path generation (pricing). Therefore, the problem itself is suspected to be NP-hard - this, however, is not actually known. The main result of

Disputationer 2022

Anders SjögrenStraffrättsliga förhållningsregler – En rättsvetenskaplig studie av förbuds-, påbuds- och permissivregler som riktar sig till enskildaDatum för disputation: fredagen den 14 oktoberFakultetsopponent: professor em Dan Frände, Helsingfors universitetÄmne: straffrättAbstractThis thesis focuses on conduct rules in criminal law. Such rules prohibit, proscribe and permit different courses o

https://www.jur.lu.se/forskning/disputationer/disputationer-2022 - 2026-05-23