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The cytokine TGFβ1 induces epidermal Langerhans cell (LC) differentiation from human precursors, an effect mediated through BMPR1a/ALK3 signaling, as revealed from ectopic expression and receptor inhibition studies. Whether TGFβ1‒BMPR1a signaling is required for LC differentiation in vivo remained incompletely understood. We found that TGFβ1-deficient mice show defective perinatal expansion and di

Someone who throws away their rubbish on a street-corner or in a ditch is guilty of sloth. This may appear harmless, but seen through the lens of waste management, sloth soon develops into a deadly sin that harms other people’s lives and health. Hiding and forgetting waste has always been a practice with potentially disastrous consequences; buried containers full of toxins will eventually start to

CMKLR1 (chemoattractant-like receptor 1) is a G-protein-coupled receptor implicated in cartilage and bone development and is expressed in organs like the parathyroid gland, brain, and lung. The receptor is also expressed in dendritic cells and in macrophages where it acts as a co-receptor for entry of HIV/SIV isolates into human CD4(+) cells. Recently, a protein named "chemerin" (also known as TIG

Compression anastomotic ring-locking procedure (CARP) is a novel procedure for creating colonic anastomoses. The surgical procedure allows perioperative quantification of the compression pressure between the intestinal ends within the anastomosis and postoperative monitoring of the anastomotic integrity. We have recently shown that CARP is a safe and effective method for colonic anastomoses in pig

Type II collagen (CII) is a candidate cartilage-specific autoantigen, which can become post-translationally modified by hydroxylation and glycosylation. T cell recognition of CII is essential for the development of murine collagen-induced arthritis (CIA) and also occurs in rheumatoid arthritis (RA). The common denominator of murine CIA and human RA is the presentation of an immunodominant CII-deri

This study explored the role of secreted fibroblast-derived factors in prostate cancer growth. Analyses of matched normal and tumor tissue revealed up-regulation of CXCL14 in cancer-associated fibroblasts of a majority of prostate cancer. Fibroblasts overexpressing CXCL14 promoted the growth of prostate cancer xenografts, and increased tumor angiogenesis and macrophage infiltration. Mechanistic st

Background: A trial fibrillation (AF) is a common problem in pacemaker patients. We conducted a prospective observational study in patients paced for bradycardia with associated paroxysmal or persistent AF, to determine whether P-wave duration may stratify patients at higher risk for AF recurrences and AF-related hospitalizations. The patients were evaluated for the prevalence, cause, and predicto

BACKGROUND: Recent studies have found that particulate matter (PM) attached radioactivity was associated with certain adverse health effects including increased blood pressure and lung dysfunction. However, there has been no investigation on the direct effect of PM radioactivity on mortality.METHODS: Exposures to ambient PM gamma activities were determined using U.S. EPA RadNet data. Data on daily

Collective harm cases are situations in which things will become worse if enough acts of a certain kind are performed but no single act of the relevant kind will make a difference to the outcome. The inefficacy argument says that since one such act does not make a difference to the outcome, you have no outcome-related reason to refrain from acting in this way. If this argument holds, you have no cCollective harm cases are situations in which things will become worse if enough acts of a certain kind are performed but no single act of the relevant kind will make a difference to the outcome. The inefficacy argument says that since one such act does not make a difference to the outcome, you have no outcome-related reason to refrain from acting in this way. If this argument holds, you have no c

Muller cells are the principle glia cells of the retina that maintain the integrity and function of the retina and are thought to support and protect neurons during various insults. α2-adrenergic receptor agonists have been shown to be neuroprotective and Mu[[unable to display character: ̈]]ller cells are suggested to take part in these effects. The purpose of this project was to study th

PurposeThe Physical Internet (PI) is an emerging concept that applies the Digital Internet as a design metaphor for the development of sustainable, interoperable and collaborative freight transport. With the aim of aiding researchers and policy makers in their future efforts to develop efficient logistics systems, the purpose of this paper is to present a review of the existing literature on the P

Background: Anillin (ANLN), an actin-binding protein required for cytokinesis, has recently been presented as part of a prognostic marker panel in breast cancer. The objective of the current study was to further explore the prognostic and functional value of ANLN as a single biomarker in breast cancer. Methods: Immunohistochemical assessment of ANLN protein expression was performed in two well cha

The ability to form long-term memories exists very early during ontogeny; however, the properties of early memory processes, brain structures involved and underlying cellular mechanisms are poorly defined. Here, we examine the role of extracellular signal-regulated kinase (ERK), a member of the mitogen-activated protein kinase/ERK signaling cascade, which is crucial for adult memory, in the consol

This paper explores the relationship between democratization and economic redistribution using case study analysis applied to Sweden and Brazil. We find that democratization is intimately connected to redistribution through the welfare state, but as an event in itself is neither a necessary nor a sufficient cause of redistributive reforms. Democratization is not strictly necessary, because in anti

NGEK01_VT16_Final_Course_Evaluation_2 Kopia av NGEK01_VT16 Antal svar: 11 Ange kursens (dvs de schemalagda delarna) övergripande kvalitet. (1 = Mycket dålig, 2 = Dålig, 3 = OK, 4 = Bra 5 = Mycket bra) Ange kursens (dvs de schemalagda delarna) övergripande kvalitet. (1 = Mycket dålig, 2 = Dålig, 3 = OK, 4 = Bra 5 = Mycket bra) Antal svar 1 0 (0,0%) 2 0 (0,0%) 3 2 (18,2%) 4 5 (45,5%) 5 4 (36,4%) Sum

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/ngek01_vt16_final_course_evaluation.pdf - 2026-07-17

Professor, Programchef - Magisterprogram i Dataanalys och ekonomi Kontaktinformation E-post: joakim [dot] westerlund [at] nek [dot] lu [dot] se Telefon: +46 46 222 89 97Organisation Nationalekonomiska institutionen Rumsnummer: Alfa1:4027 Hämtställe: 10 WebbplatsJoakim Westerlunds profil i Lunds universitets forskningsportalPersonlig webbplats:https://sites.google.com/site/perjoakimwesterlund/ Publ

https://www.ehl.lu.se/joakim-westerlund - 2026-07-16