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Rationale: Cardiopulmonary exercise testing (CPET) is the gold standard to evaluate exertional breathlessness, a common and disabling symptom. However, the interpretation of breathlessness responses to CPET is limited by a scarcity of normative data. Objectives: We aimed to develop normative reference equations for breathlessness intensity (Borg 0–10 category ratio) response in men and women aged
Scanning coherent X-ray microscopy (ptychography) has gained considerable interest during the last decade since the performance of this indirect imaging technique does not necessarily rely on the quality of the X-ray optics and, in principle, can achieve highest spatial resolution in X-ray imaging. The method can be easily extended to 3D by adding standard tomographic reconstruction schemes. Howev
Using examples from Poland, Elżbieta Drążkiewicz explores the question of why states become donors and individuals decide to share their wealth with others through foreign aid. She comes to the conclusion that the concept of foreign aid requires the establishment of a specific moral economy which links national ideologies and local cultures of charitable giving with broader ideas about the global
Background: This study investigated the association of two levels of targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA) with administered doses of sedative and analgesic drugs, serum concentrations, and the effect on time to awakening. Methods: This substudy of the TTM2-trial was conducted at three centers in Sweden, with patients randomized to either hypothermia or
Background: We aimed to evaluate cumulative occurrence and impact of COVID-19 in patients with chronic respiratory failure (CRF) treated with long-term oxygen therapy (LTOT). Material and methods: Data were obtained from the SCIFI-PEARL study on the entire Swedish population and on patients with oxygen-dependent CRF and no COVID-19 diagnosis before start of LTOT. Analyses were performed for three
This article examines the historical genesis, nature, features and international legal status of the Institute representation at the UN, both on the territory of the member states and of the member states to the UN. An attempt was made to reveal the status and characteristics of the offices of both the UN and its specialized agencies. On the basis of the analysis, proposals were made to strengthen
Flowing water impacts bridges over rivers primarily in two ways: (1) hydrodynamic forces that directly impact the structure and (2) scouring at piers and abutments, including contraction scour. The design prin-ciples for bridges in Sweden, including both impacting forces and local scour, are relatively simplistic. The purpose of this paper is to examine the impact of extreme river flows on bridges
In response to escalating disasters, inclusive crisis planning is crucial. This study examines a specialized workshop that engaged people with disabilities in crisis planning, focusing on a simulated flood scenario. Stakeholders from disability organizations and the local municipality collaborated, including eight crisis communicators and thirteen individuals with disabilities. The workshop facili
Earlier treatment of breast cancer results in better survival. Screening enables this through detection of tumors before they cause symptoms. On the negative side, some tumors if not detected through screening would not cause symptoms, leading to overdiagnosis. Improvements in image quality allow even earlier detection and diagnosis of even smaller tumors at an even earlier stage. This study aims
Collaboration in governing complex environmental challenges is the norm. However, collaboration does not necessarily deliver desirable outcomes, and the importance of forming collaborative networks that effectively address the challenges at hand has been emphasized in theory and practice. Evidence for what constitutes a suitable network structure is still scarce, and the understanding of what fact
The chapter discusses the importance of the EU continuing to promote improved living and working conditions for its citizens without simultaneously risking competition between workers from different member states. The problem discussion is based on the significance of social improvements for the EU to maintain support among citizens and the challenges that arise when EU law encounters the differen
Three different semiconductor nanowires are combined into a single optoelectronic artificial neuron. Our device provides a path towards low power computations with significantly reduced circuit footprint, thus addressing critical limitations in neuromorphic photonics. The false-coloured scanning electron micrograph shown in Figure 1a depicts the fabricated nanowire neuron. Two pin-doped InP nanowi
Photonics-based approaches to neuromorphic hardware offer advantages in speed and connectivity but often suffer from large device footprints.[1] Here, we present an ultra-compact artificial neuron built from semiconductor nanowires. A scanning electron micrograph of the nanowire device is presented in Figure 1a. Inside the dashed box, we show the neuron built from three III-V nanowires - two InP p
In this article, I explore the assigned role of interpreters in journalism training programmes in Vietnam, focusing on two media aid projects funded by the Swedish International Development Cooperation Agency (Sida): the Local Radio Project and the Further Training of Journalists programme. The study is based on qualitative analyses of project documentation and interviews with former trainers. A t
BackgroundLong-term oxygen therapy (LTOT) given for at least 15 hours/day improves survival in patients with severe chronic hypoxemia. However, the recent REDOX trial showed that LTOT prescribed for 24 hours/day was not superior to 15 hours/day in terms of death, hospitalizations, or self-reported outcomes. We aimed to examine the cost effectiveness of prescribing LTOT for 24 versus 15 hours/day.M
Objectives: Both depression and suicidal behaviour have been associated with neuroinflammation. Galectin-3 (Gal-3), a protein involved in microglial activation, has been linked to pro-inflammatory cytokines and the severity of depressive symptoms. The extent to which peripheral levels of Gal-3 reflect neuroinflammation is unknown, as is the relationship between Gal-3 and suicidality. Methods: Bloo
Children undergoing surgery for posterior fossa tumours (PFT) may experience postoperative language and communication difficulties, regardless of whether they develop cerebellar mutism syndrome (CMS) or not. While these language difficulties are increasingly recognised in current research, children’s own experiences of everyday communication remain limited. In this presentation, we share findings
Introduction: Oxidating fat as an energy substrate requires more oxygen than utilizing carbohydrates and can be acutely increased by hyperoxia. Therefore, substrate utilization may affect endurance performance and gas consumption in divers, but previous research is limited. This study aimed to evaluate changes in maximal fat oxidation (MFO) in navy divers during training. Methods: Seven explosive
