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Glutamatergic transmission is an important factor in the development of neuronal death following transient cerebral ischemia. In this investigation the effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on neuronal damage were studied in rats exposed to 10 min of transient cerebral ischemia induced by bilateral common carotid occlusion combined with hypotension. The animals w
Optical coherence tomography angiography (OCT-A) is a non-invasive, non-dye-based imaging modality that has the potential to enhance our understanding of retinal diseases. While this rapidly advancing imaging modality offers great potential, there is a need for community-wide understanding of the range of technologies and methods for interpreting the images, as well as a need to enhance understand
Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in the reaction mixtures. The chymotrypsin-catalyzed reaction between Z-Phe-OMe and Leu-NH2 was used as a model reaction. Under the conditions used ([Z-P
It is estimated that about 30 000 people a year are successfully resuscitated after having suffered an out-of-hospital cardiac arrest in Europe. The number of patients that are successfully resuscitated after an in-hospital cardiac arrest is not known, but it can be assumed that this figure is even higher than that after an out-of-hospital cardiac arrest. The aim of the Swedish Resuscitation Counc
The selling or procuring of sexual services was never an uncontroversial part of the everyday exchange of goods and services in Western culture. Instead, it has been represented as a problem since (at least) the Middle Ages, and the problem descriptions have had different functions as the social, economic and cultural organisation of society was changing. Men selling sex to men, on the other hand,
Software-Defined Networking (SDN) is a novel architectural model for cloud network infrastructure, improving resource utilization, scalability and administration. SDN deployments increasingly rely on virtual switches executing on commodity operating systems with large code bases, which are prime targets for adversaries attacking the network infrastructure. We describe and implement TruSDN , a fr
An increasing number of patients are successfully resuscitated from cardiac arrest (CA) and subsequently treated in an intensive care unit due to unconsciousness. Approximately half of these patients will die during the first weeks postarrest, typically after a determination of a poor neurologic prognosis and a decision to withdraw life-sustaining therapy (WLST). These decisions are guided by univ
Bolagsordningar och aktieägaravtal skapar en hel del rättsfrågor, både individuellt och ihop. Många problem rör rättshandlingarnas rättsverkningar och vad verkningarna innebär för aktieägarna, bolaget och övriga avtalsparter. Dessa rättsfrågor har utretts i denna text och särskild hänsyn tagits till hur skydd för svagare part formar och påverkar rättsverkningarna för bolagsordningen och aktieägaraArticles of association and shareholders’ agreements create many legal issues both individually and together. Many of the problems revolve around the legal effects of the acts; what the effects entail for the shareholders, the company and other contractors. These questions have been examined in this text and special regards have been given to how protection for weaker parts form and affect the leg
Public Private Partnership, PPP, is a public procurement method involving the private sector used in several countries all over the world, now upcoming in Sweden. The UK, most prominent within this method, states that it offers good value for money, but the economic and financial benefits of PPP are still uncertain and subjects of debate. In order for the projects to be successful and to achieve v
År 2015 samlades världens ledare och antog 17 globala hållbarhetsmål för att bidra till en social, ekonomisk och miljömässigt hållbar utveckling. De 17 globala hållbarhetsmålen utgör Agenda 2030 och ansvaret för genomförandet av agendan vilar på medlemsländernas regeringar. För att uppnå agendan måste alla sektorer engagera sig. Det innebär att kommunal räddningstjänst som är en del av den kommunaThe importance of sustainability is constantly increasing in today’s society and 2015 the United Nations adopted 17 global sustainable development goals (SDGs), summarized as the “2030 Agenda”. To achieve the 2030 Agenda all sectors must become involved which means that the Fire and Rescue Services (FRS) must contribute to this sustainability work. It is therefore important to map how the Swedish
The Aviation industry is ultra-safe. Rules and procedures have been attributed as a contributory factor for attaining this high level of safety. The complexity of the aviation system has risen dramatically in the last few decades due to the development and introduction of modern aircraft and on-board technological innovations. Every day pilots encounter situations they did not expect. During those
An increase in large-scale agricultural investment in land has been going on since the global food crisis in 2008. Import-dependent countries have acquired large plots of land to secure food supplies. The investments had disastrous impacts on the local communities living on the land before the investment took place. Many have been expropriated and evicted from their lands, affecting their human ri
Viktigt för rättssäkerheten i Sverige är att ingen ska kunna dömas oskyldig och att medborgare anklagade för brott ska betraktas som oskyldiga till dess att motsatsen bevisats. Misstag sker dock och därför finns regler kring resning i brottmål till förmån för den tilltalade i 58 kap. 2 § Rättegångsbalken (RB). Rättelse kan därmed nås genom att den dömde begär resning och på så sätt får sin dom ompIt is of importance that citizen’s accused of crime is seen as innocent until proven guilty and no one should be innocently convicted. But mistakes happen and therefor there are rules for granting convicted citizens a new trial in 58 kap. 2 § Rättegångsbalken (RB). It is essential in a legal certain society that a verdict which has gained legal force is not easily removed, but as previously menti
I samband med att multinationella företag växt fram och fått en ökad betydelse och räckvidd i vår nu globaliserade ekonomi, har företagens sociala ansvar blivit en uppmärksammad och mycket aktuell fråga. Andra faktorer såsom klimatförändringar, mänskliga rättigheter och arbetsförhållanden har också bidragit till ökade krav på ansvar. Ett antal internationella standarder och rekommendationer på omr
