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Popular Abstract in Swedish Kväveoxid (NO) och framför allt kolmonoxid (CO) tillhör de giftigaste gaserna man känner till. Vem har inte läst i kriminalromaner om hur människor stängts in i garage och gasats ihjäl med kolmonoxid från arbetande bilmotorers avgasutsläpp. Under det senaste årtiondet har man kunnat visa att dessa gaser i själva verket bildas i vår egen kropp och att de utgör signalmoleDuring the last decade it has been shown that nitric oxide (NO) and carbon monoxide (CO) are produced in our own body, and that they constitute a novel class of messenger molecules. In 1992 a constitutive NO-producing NO-synthase (cNOS) was found in the islets of Langerhans, and in 1997 we could show for the first time that the islets also contained a CO-producing constitutive heme oxygenase (HO-2

Popular Abstract in Swedish Hur man värderar resultat av kirurgisk behandling av ländryggens degenerativa åkommor är ett stort, komplext och delvis kontroversiellt ämne. Denna avhandling studerar resultatvärdering med olika metoder och instrument, huvudsakligen baserat på resultat från det nationella svenska ländryggskirurgiregistret. Arbete I. Inventering av befintliga instrument i litteraturen No consensus regarding outcomes assessment in spine patients exists. Health-Related Quality of Life (HRQoL) questionnaires are increasingly used. The objective of this thesis was the evaluation of HRQoL measures before and after lumbar spine surgery, and their relation to other evaluation parameters as well as relevance of differences. The patients included were operated on for lumbar spine disor

The citations of highly cited papers in the life sciences published in 1986 and 2000 was examined to determine the extent to which early impact predicts long term impact. Linear correlation between early and post-peak impact was found to be about 0.7

Bakgrund: Antalet personer som drabbas av demenssjukdomar ökar kraftigt och anhöriga till dessa påverkas i vardagen på olika sätt, vilket kan påverka deras hälsa. Syfte: Syftet med denna studie var att undersöka upplevelsen av aktivitetsbalans hos anhöriga till personer med demens. Metod: Data inhämtades genom en fokusgrupp vid två upprepade tillfällen med 5 deltagare. En riktad innehållsanalys ge

Home mechanical ventilation (HMV) is increasingly used as a therapeutic option to patients with symptomatic chronic hypoventilation. There is, however, a paucity of solid data on factors that could affect prognosis in patients on home ventilation. In the present study, our aim was to study several factors in these patients with potential influence on survival. We examined 1526 adult patients from

Popular Abstract in Swedish Det har traditionellt sett varit mycket svårt att genomföra förbränningsstudier i motorer, men i och med laserns introduktion har nya möjligheter öppnats. Under de senaste 20 åren har lasern blivit ett allt viktigare hjälpmedel, och ett stort antal laser baserade mätmetoder har utvecklats. Det är nu möjligt att mäta temperaturer, ämneskoncentrationer, hastighetsfält ochMulti-dimensional, laser-based measurements of quantities important for obtaining a better understanding of combustion processes, particularly of temperature and of species distributions, were performed using laser-induced fluorescence (LIF). The main purpose of the temperature experiments was to investigate the potential of employing a two-line atomic fluorescence technique (TLAF), using indium a

Vårt syfte med uppsatsen är att undersöka om det skett en förändring i svensk utvecklingspolitik sedan de nya riktlinjerna lanserades i propositionen PGU från 2002. Vårt mål är att urskilja vilka diskurser som är genomgående, hur dessa diskurser relationellt har påverkat varandra och hur de inbördes har förändrats över tid. Hur ser regeringen på utveckling, fattigdom och bistånd? Har det skett en

Den ökade digitaliseringen av ekonomin har medfört betydande utmaningar för traditionella skattesystem, särskilt i fråga om beskattning av multinationella företag med omfattande digital närvaro men utan fysisk etablering. Detta har lett till rättvisa konkurrensförhållanden mellan den digitala och den traditionella marknaden samt mellan olika staters skattebaser. Mot denna bakgrund har digital beskThe increasing digitalisation of the economy has led to significant challenges to traditional tax systems, particularly with regard to the taxation of multinational enterprises with substantial digital presence but no physical establishment. This has led to unequal competitive conditions between the digital and traditional markets, as well as between different states’ tax bases. Against this backg

Carotid sinus massage (CSM) is essential in evaluating recurrent unexplained reflex syncope, as it uniquely identifies cardioinhibitory forms that other tests may miss. CSM is largely underused in clinical practice outside dedicated syncope facilities and, when performed, its execution varies, as does the interpretation of results. Underuse affects the diagnostic yield of CSM in the syncope evalua

Membrane-bound water channels known as aquaporins (AQPs) facilitate water transport across biological membranes along osmotic gradients. Since all living cells depend on their ability to maintain water homeostasis, this must be tightly regulated. In eukaryotes, this is achieved by gating, which involves a conformational change of the protein, thereby physically blocking water transport, or by traf

Common remediation and land management approaches often preclude economically attractive and low risk brownfield redevelopment. The authors argue that recently developed dynamic site characterization techniques can greatly improve sound decision making on land revitalization options. A number of these in-situ soil and groundwater test methods, such as MIP, ROST™/UVOST™, XRF and BAT, based on geote

The last two decades have seen a significant increase in the number and quality of cross-national measures of institutions, which are also covering longer and longer time spans. However, despite the considerable progress that has been made, important measurement issues linger. This chapter argues that the key future challenge for the measurement of institutions is how to square objective or direct