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Background: Circulating tumor cells (CTCs) carry independent prognostic information in patients with metastatic breast cancer (MBC) on different lines of therapy. Moreover, CTC clusters are suggested to add prognostic information to CTC enumeration alone but their significance is unknown in patients with newly diagnosed MBC. We aimed to evaluate whether longitudinal enumeration of circulating tumo
AIMS/HYPOTHESIS: Patients with Type I (insulin-dependent) diabetes mellitus have a reduced transcapillary fluid absorption from skeletal muscle and skin and thus defective plasma volume regulation during hypovolaemia. Our aim was to find whether a defective capillary filtration coefficient or impaired transcapillary driving force are aetiologic factors for this reduction.METHODS: We investigated 1
Abstract to PLANNORD 2019: Future challenges for Nordic planning
Objective: To assess the relative validity of two diet assessment methods, an extensive quantitative food frequency questionnaire (method A) and a novel shorter quantitative food frequency questionnaire with a 14 day food record (method B). Design: A randomized prospective cohort study. Setting: General community. Subjects: 206 residents of the town of Malmö, aged between 50-69 years, 101 men and
Background: No definite consensus has been reached yet on the best treatment strategy for the large group of infants hospitalised with bronchiolitis or pneumonia. Minimal handling is often recommended, although not evaluated scientifically. There is a need to evaluate the management, as the infants often are critically affected, and the costs for society are high. The aim of this RCT was to evalua
Monitoring insects of different species to understand the factors affecting their diversity and decline is a major challenge. Laser remote sensing and spectroscopy offer promising novel solutions to this. Coherent scattering from thin wing membranes also known as wing interference patterns (WIPs) have recently been demonstrated to be species specific. The colors of WIPs arise due to unique fringy
The central nervous system coordinates movement through forces generated by motor units (MUs) in skeletal muscles. To analyze MUs function is essential in sports, rehabilitation medicine applications, and neuromuscular diagnostics. The MUs and their function are studied using electromyography. Typically, these methods study only a small muscle volume (1 mm3) or only a superficial (<1 cm) volume of
Background and Purpose: For pelvic magnetic resonance imaging (MRI)-only radiotherapy the use of receiver coil bridges (CB) is recommended to avoid deformation of the patient. Development in coil technology has enabled lightweight, flexible coils. In this work we evaluate the effects of a lightweight coil in a pelvic MRI-only radiotherapy workflow. Materials and Methods: Twenty-one patients, refer
The Online Remote Behavioural Intervention for Tics (ORBIT) trial found that an internet-delivered, therapist-supported, and parent-assisted Exposure and Response Prevention (ERP) intervention reduced tic severity and improved clinical outcomes. This process evaluation aimed to explore mechanisms of impact and factors influencing efficacy. Participants were 112 children with a tic disorder and the
A high acoustic energy density is required in the acoustic resonator to increase the throughput of acoustophoresis devices. In this study, through both experiments and numerical simulations, we find that the energy density in bulk-wave-acoustophoresis devices can be enhanced by actuating the device from the side. Based on qualitative free-flow focusing experiments, side actuation shows clear super
Many nanoadsorbents are reported in the literature, exhibiting remarkable properties in the removal of low concentrations of toxic metals. However, their environmental performance has not yet been well studied. A life cycle assessment (LCA) was carried out for a previously reported nanomaterial-based adsorbent, silicate-titanate nanotubes chitosan beads (STNTs-Ch beads), used to remove cadmium fro
AIMS: Lumbar disc prolapse is a frequent indication for surgery. The few available long-term follow-up studies focus mainly on repeated surgery for recurrent disease. The aim of this study was to analyze all reasons for additional surgery for patients operated on for a primary lumbar disc prolapse. METHODS: We retrieved data from the Swedish spine register about 3,291 patients who underwent primar
In its proposed 2023 Critical Raw Materials Act, the European Commission considers access to critical raw materials within its territory as key to both the green transition and to reduce import dependencies. This onshoring of extractivist practices warrants a critical analysis that reflects on the justice implications this may have for local communities. Therefore, I apply an integrated post-struc
Border carbon adjustment is an economic instrument being discussed more frequently as a possible solution to address carbon leakage, which is an issue for many developed countries. Developed countries are showing interest in this instrument to protect domestic industries from carbon leakage to countries that do not tax carbon. There is however concerns from developing countries that border carbon
To stay within our planet’s limits and reach the United Nation’s Sustainable Development Goals, there is an urgent need to rethink our current and dominant systems. This thesis focuses on the food system, in particular, and explores how an overarching turnaround in the way we produce and consume food has the potential to trigger and steer a greater transition towards sustainability. However, this
Klimatförändringen förväntas orsaka 20-25% kraftigare regnoväder i Sverige vilket, tillsammans med urbaniseringen, ökar sannolikheten för översvämningar i urbana områden. En översvämningen kan innebära stora materiella skador och kostnader för samhället. För att förebygga dessa behövs mer kunskap om vilka områden i staden som är mest utsatta. Information om var och när stora vattenmängder väntas kClimate change is expected to cause 20-25% heavier rainfall in Sweden which, in combination with the ongoing urbanization, increases the probability of flooding in urban areas. These floods may cause large infrastructural damage and economical costs. Therefore, adequate models for overland flow are needed to identify high-risk areas where mitigating actions should be performed. In this thesis a ne
The symbolic elite discourse on the safety and viability of using the insecticide DDT for combating malaria in Africa is marked by extreme dissonance. While some positions within the debate on using DDT for malaria prevention are quite nuanced, others are more extreme if not one-dimensional. The ones who tend to hold more nuanced or centrist positions on using DDT for controlling malaria are often
Roots play a key role in terrestrial carbon and water cycles, and therefore for the global climate system. They mediate plant evapotranspiration, influence photosynthetic processes and are responsible for atmospheric carbon transport into the pedosphere. Fine roots, in particular, are chiefly regulating water and nutrient uptake. Recent research has suggested that the representation of fine roots
