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The hematopoietic system is responsible for transporting oxygen and nutrients, fighting infections, and repairing tissue damage. Hematopoietic system dysfunction therefore causes a range of serious health consequences. Lifelong hematopoiesis is maintained by repopulating multipotent hematopoietic stem cells (HSCs) that replenish shorter-lived, mature blood cell types. A prokaryotic mechanism of im
Purpose: Recently, there has been increasing interest in the use of dual mobility systems in the treatment of hip instability. The aim of this study was to investigate the re-revision rate of dual mobility cup compared to different surgical concepts when used for first-time hip revisions due to recurrent dislocations. Methods: The data were derived from the Lithuanian Arthroplasty Register. For su
The aim of our study was to experimentally investigate whether it is possible to reduce nuisance growth of filamentous algae in freshwater ecosystems. We used an experimental set-up mimicking a shallow pond system and performed a field investigation in the eutrophic moat of Krapperup castle (Southern Sweden), which exemplifies an extremely impaired ecosystem with ample growth of filamentous green
The self-assembly of small colloidal clusters, so-called colloidal molecules, into crystalline materials has proven extremely challenging, the outcome often being glassy, amorphous states where positions and orientations are locked. In this paper, a new type of colloidal molecule is therefore prepared, assembled from poly(N-isopropylacrylamide) (PNIPAM)-based microgels that due to their well docum
Aims: Iron deficiency (ID) is a common co-morbidity in heart failure (HF), associated with impaired functional capacity, poor quality of life and increased morbidity and mortality. Treatment with intravenous (i.v.) ferric carboxymaltose (FCM) has shown improvements in functional capacity, symptoms and quality of life in stable HF patients with reduced ejection fraction. The effect of i.v. iron sup
Utvärdering RALS2019 (210331) Sida 1 (10) Saco-S-föreningen vid Linnéuniversitetet Saco-S utvärdering av RALS 2019 Under år 2019 genomfördes för fjärde gången lönesättande samtal som gene- rellt tillvägagångssätt för samtliga medlemmar anslutna till ett fackförbund inom Saco-S vid Linnéuniversitetet. Som grund för lönesättningsprocessen fanns en överenskommelse som tyvärr inte blev undertecknad fö
Klebsiella pneumoniae is a major opportunistic pathogen, where the polysaccharide capsule is traditionally recognized as a critical virulence determinant. However, its role in surface interactions and intracellular adaptation remains incompletely understood. Here, we combined phenotypic assays with physicochemical analyses to dissect the contribution of the capsule. A wza knockout mutant displ
The Circular Economy (CE) concept is widely promoted as a pathway to sustainability, yet its practical realization can appear to be challenging and unclear due to divergent definitions, interpretations and understanding about the implications and goals of a realized CE. Addressing this gap, this study develops the Circular Economy Loop Strategies (CELS) Framework, a synthesizing foundational model
This chapter reviews the historical development of the regulation of waste and chemicals in both international law and European Union (EU) law after the 1972 Stockholm Conference as well as some of the subsequent trends and themes. It also highlights the relevant interactions between EU and international law on these issues. The chapter ends with a discussion of how the regulatory frameworks relat
Syftet med uppsatsen är att studera och analysera hur en räntehöjning respektive -sänkning påverkar aktiekursen samt om det föreligger någon skillnad mellan olika branscher och soliditetsnivåer. Vi har genomfört en kvantitativ studie, en händelsestudie, av totalt 60 svenska företag fördelade på sex olika branscher, alla noterade på Stockholmsbörsen. Vi har beräknat den onormala avkastningen för al
Modern society depends on dams for renewable hydropower, water supply, and flood control. As climate change increases the frequency of extreme rainfall and flood events, and as the demand for renewable energy sources continues to grow, ensuring the safety of these critical structures becomes more urgent than ever. One of the most serious hidden threats in embankment dams is internal erosion – a sl
Biogenic ice-nucleating particles (INPs) can significantly impact mixed-phase clouds by enhancing precipitation and reducing albedo. As Arctic sea ice diminishes, the exposure of open ocean may increase aerosolization rates of marine bioaerosols and INPs. We investigated INP concentrations and microbial communities in ambient marine air, sea bulk water (SBW), and sea surface microlayer (SML) along
Like other Western legal systems, the Swedish legal system constructs objectivity as an unemotional state of being. We argue that the enactment of objectivity in situ relies on objectivity work including emotion management and empathy. Building on qualitative interviews and observations in Swedish district courts, we analyse courtroom interaction through a dramaturgical lens, highlighting tacit siLike other Western legal systems, the Swedish legal system constructs objectivity as an unemotional state of being. We argue that the enactment of objectivity in situ relies on objectivity work including emotion management and empathy. Building on qualitative interviews and observations in Swedish district courts, we analyse courtroom interaction through a dramaturgical lens, highlighting tacit si
Background: Low-cost particulate matter sensors have enabled new opportunities for exposure monitoring but require evaluation before application in epidemiological studies. This study assessed the performance of the SPS30 sensor integrated into the ARMIE portable monitoring sensor-node under controlled laboratory conditions. Methods: Sensors were co-located with two comparison instruments—the opti
Shibanqiao Reservoir (0.24 km(2)) and Xiaohe Reservoir (0.28 km(2)) have catchments of 6.00 km(2) and 22.69 km(2), respectively. They essentially represent "strongly eroded" (Shibanqiao) and "mildly eroded" (Xiaohe) regions in Guizhou Plateau, southwestern China. Sediment cores were retrieved from the two reservoirs and soils were also sampled from their catchments. Mineral magnetic measurements w
Transplantation of hematopoietic stem cells (HSCs) to treat hematological disorders is routinely used in the clinic. However, HSC therapy is hindered by the requirement of finding HLA-matched donors, as well as attaining sufficient numbers of long-term HSCs in the graft. Therefore, ex vivo expansion of transplantable HSC remains one of the "holy grails" of hematology. Without the ability to mainta
Abstract For nanotoxicology investigations of air-borne particles to provide relevant results it is ever so important that the particle exposure of, for example cells, closely resembles the "real" exposure situation, that the dosimetry is well defined, and that the characteristics of the deposited nanoparticles are known in detail. By synthesizing the particles in the gas-phase and directly deposi
Popular Abstract in Swedish I Sverige har andelen förtidspensionärer ökat under lång tid och uppgick år 1998 till 7.6% av befolkningen i arbetsför ålder (16-64 år). Den vanligaste orsaken till att en individ förtidspensioneras är reducerad arbetsförmåga till följd av problem i rörelseorganen. Kunskaperna om förtidspensionärers livskvalitet är bristfälliga. Syftet med denna studie var att studera lThe starting-point of this thesis was the high rate of disability pensioners in Sweden and the lack of knowledge about what a disability pension entails for quality of life (QL). The aim of the study was to gain knowledge about QL among disability retirees with musculoskeletal disorders (ERPs). A questionnaire was sent in 1992 to 450 ERPs in Kristianstad Municipality, Sweden, granted their disabil
The proto-oncogene SKI is highly expressed in human myeloid leukemia and also in murine hematopoietic stem cells. However, its operative relevance in these cells remains elusive. We have over-expressed SKI to define its intrinsic role in hematopoiesis and myeloid neoplasms, which resulted in a robust competitive advantage upon transplantation, a complete dominance of the stem and progenitor compar
