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Objective Ultrasound is a promising tool to foster much-needed improvement of skin assessment in systemic sclerosis (SSc). Our aim was to develop evidence and expert opinion-based recommendations to promote the standardisation and harmonisation of technical execution and reporting of skin ultrasound studies in SSc. Methods A multidisciplinary task force of 16 members from five European countries a
Many astrophysical observations indicate the existence Dark Matter, which is not predicted by the Standard Model (SM) of particle physics. Many theories beyond the Standard Model (BSM) predict new heavy particles called WIMPs (Weakly Interacting Massive Particles). One way to search for WIMP dark matter is through its pair-production in collider experiments. A possible signature, in this case, is
The risk assessment of pesticide residues in food is a key priority in the area of food safety. Most jurisdictions have implemented pre-marketing authorization processes, which are supported by prospective risk assessments. These prospective assessments estimate the expected residue levels in food combining results from residue trials, resembling the pesticide use patterns, with food con-sumption
Objectives: To assess the prevalence of reported and unreported incidental pulmonary embolism (iPE) in patients with cancer, and to evaluate an artificial intelligence (AI) algorithm for automatic detection of iPE. Methods: Retrospective cohort study on patients with cancer with an elective CT study including the chest between 2018-07-01 and 2019-06-30. All study reports and images were reviewed t
Working Mexican mothers have been experiencing drastic changes in their way of life due to the forced adaptation of their office work into a ‘Home office’ mode. The reason of this sudden change was brought by the Covid-19 pandemic which prompted governments and companies to enforce lockdowns and social distancing as measures to prevent the contagion. This pushed working women to juggle work and ho
This study explores the different psychological processes and psychological capital resources that help entrepreneurs sustain motivation to re-enter entrepreneurship after discontinuing a previous venture. While existing literature has focused intensely on the financial and social costs of business failure, minimal yet growing scholarly attention has focused on the psychological costs of failure a
This study explores the interdependencies and cascading effects in the disaster response management for a possible 7.2 magnitude earthquake scenario in Metro Manila, focusing on the role of the Cordillera Administrative Region (CAR) as the primary assisting region. The research is grounded in Complexity and Socio-Technical Network Theory, which provides that the disaster response management is a c
Drinking water distribution systems directly affect the quality of life, public health, and the reliability of essential water services. This study evaluates the hydraulic performance and operational efficiency of the Kirke Eskilstrup drinking water distribution network in Denmark using hydraulic modelling in MIKE+. Furthermore, a stakeholder value analysis was included to identify how the modelli
This thesis explores arguments and styles of argumentation in favour of Scotland gaining independence and rejoining the European Union in the aftermath of the United Kingdom leaving the EU in 2020. Since a majority of Scots did not support Brexit, it has provided Scottish independence supporters with a unique opportunity to bolster their arguments in the political debate. The thesis is built on a
Environmental and health risks are increasing in large Mediterranean cities like Athens, where high urban density and limited vegetation intensify the Urban Heat Island (UHI) effect. This study analyzes the spatial patterns of surface urban heat in Athens, Greece, using satellite-derived Land Surface Temperature (LST) as a proxy for UHI conditions. LST datasets were derived from Landsat 8 thermal
Background: Less adults with cerebral palsy (CP) lives independently, compared to adults without disabilities. Access to personal assistance may help overcome barriers to independent living. Also, little is known about hand function in adults with CP, and the role of hand function in achieving independent living remains unexplored. Objective: To explore the associations between housing and persona
Computational models play an increasingly vital role in scientific research by enabling the numerical simulation of complex processes. Such models are also fundamental in geosciences. For instance, they offer critical insights into the impacts of global change on the Earth system today and in the future. Beyond their value as research tools, models are also software products and should therefore a
From the early 1990s and onwards the use of debt relief as a method of providing development assistance has become increasingly popular, especially since the launch of the HIPC initiative in 1996. This thesis aims to investigate the general theoretical and empirical support of the growth enhancing properties of debt relief with regard to low income countries. Focus is put on evaluating the harmful
Macronutrient intake, the proportion of calories consumed from carbohydrate, fat, and protein, is an important risk factor for metabolic diseases with significant familial aggregation. Previous studies have identified two genetic loci for macronutrient intake, but incomplete coverage of genetic variation and modest sample sizes have hindered the discovery of additional loci. Here, we expanded the
BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this syst
BACKGROUND: Pegylated interferon alfa plus ribavirin protocol is currently considered the most efficient hepatitis C treatment. However, no evidence of costs comparison among common viral genotypes has been published.OBJECTIVES: We aimed to assess core drivers of hepatitis C medical care costs and compare cost effectiveness of this treatment among patients infected by hepatitis C virus with genoty
Results of a search for physics beyond the Standard Model in events containing an energetic photon and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. As the number of events observed in data, corresponding to an integrated luminosity of 36.1 fb- 1 of proton–proton collisions at a centre-of-mass energy of 13TeV, is in agreement with the Standard
Background: Lack of a global consensus on the definition of advanced Parkinson’s disease (APD) and considerations for timing of device-aided therapies may result in heterogeneity in care. Objectives: To reach consensus among movement disorder specialists regarding key patient characteristics indicating transition to APD and guiding appropriate use of device-aided therapies in the management of PD
A joint analysis of five paternal half-sib Holstein families that were part of two different granddaughter designs (ADR- or Inra-design) was carried out for five milk production traits and somatic cell score in order to conduct a QTL confirmation study and to increase the experimental power. Data were exchanged in a coded and standardised form. The combined data set (JOINT-design) consisted of on
A search for supersymmetric partners of top quarks decaying as t˜1→cχ˜10 and supersymmetric partners of charm quarks decaying as c˜1→cχ˜10, where χ˜10 is the lightest neutralino, is presented. The search uses 36.1 fb−1pp collision data at a centre-of-mass energy of 13 TeV collected by the ATLAS experiment at the Large Hadron Collider and is performed in final states with jets identified as contain
