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Retinitis pigmentosa is a group of inherited retinal degenerative diseases characterized by the loss of photoreceptors and vision for which no effective treatment is available. Several animal models of retinitis pigmentosa are used to elucidate its pathogenesis and to devise therapies. The retinal degeneration (rd1) mouse is one such animal model in which rod-specific phosphodiesterase (PDE) is in

This chapter focuses on measuring spatial pattern in floodplains and reviews 108 publications from 1934-2013 to determine trends, dominant paradigms, and approaches to measuring spatial pattern in floodplains. The development of new technologies, especially those associated with remotely sensed data capture, increases the ability to quantitatively measure the spatial complexity of floodplain surfa

This dissertation aims at advancing the knowledge about the role of the labour market in the process of the technology-induced economic transformation, taking into account the variety of factors involved at micro-, meso-, and macro-levels of the economy and at different geographical scales. Empirically, the dissertation investigates the co-evolutionary dynamics of industrial restructuring and work

The current war in Ukraine has severely disrupted global food supply chains due to the significant decline in the production of grain commodities, of which Ukraine and Russia are major global suppliers. This creates problems in today’s globalised food systems. In particular, a number of countries are heavily dependent on food imports from Ukraine and/or Russia, particularly some developing nations

Songbirds have evolved diverse strategies to cope with seasonality, including long-, medium-, and short-distance migration. There is some evidence that birds with a longer migration distance deposit fuel faster. However, most studies focus on long-distance migrants. Comparisons between species with different migration distances are necessary to broaden our understanding of fueling capacity in migr

Artikeln behandlar den litauisk-amerikanske folkrättsjuristen Jacob Robinsons (1889-1977; på litauiska: Jokūbas Robinzonas) bidrag till folkrättsdoktrin och folkrättspraxis

Background: Little is known about accuracy of common risk prediction scores in elderly patients suffering from hip fractures. The objective of this study was to investigate accuracy of the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) score, Portsmouth-POSSUM (P-POSSUM) score and the Nottingham Hip Fracture Score (NHFS) for prediction of mortali

In 1822 the Parliament of the United Kingdom passed The Cruel Treatment of Cattle Act, which today is considered to be an important forerunner to modern animal protection and anti-cruelty legislation. However, the new Enlightenment attitudes to animals stemmed from an overly anthropocentric perception of the natural world and the place of the human animal in it. At the heart of the movement agains

Objectives: This study aimed to describe the clinical experience of the health-care professionals (HCPs) responsible for the introduction of methadone, for the treatment of complex cancer pain, at a low-resource hospital in India in a patient-group, burdened by illiteracy, and low socio-economic status. Materials and Methods: Ten HCPs: Four medical doctors, four nurses, one pharmacist, and one hos

As more people are surviving cardiac arrest, focus needs to shift towards improving neurological outcomes and quality of life in survivors. Brain injury after resuscitation, a common sequela following cardiac arrest, ranges in severity from mild impairment to devastating brain injury and brainstem death. Effective strategies to minimise brain injury after resuscitation include early intervention w

Static checker frameworks support software developers by automatically discovering bugs that fit general-purpose bug patterns. These frameworks ship with hundreds of detectors for such patterns and allow developers to add custom detectors for their own projects. However, existing frameworks generally encode detectors in imperative specifications, with extensive details of not only what to detect b

Large-scale ab initio calculations of the electronic contribution to the electric quadrupole hyperfine constant B were performed for the 5s25p6s1,3Po1 excited states of neutral tin. To probe the sensitivity of B to different electron correlation effects, three sets of variational multiconfiguration Dirac-Hartree-Fock and relativistic configuration interaction calculations employing different strat

The workshop brings together differing perspectives on what makes research data possible. How data is made represents an on-going negotiation between a number of elements. It reflects, firstly, the nature of disciplines and thecomplex way this is linked to cultures of research data and data sharing. Secondly, data is made across the complex temporalities within different practices of its managemen