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Galectin-8 is a carbohydrate-binding protein that plays a crucial role in tumor progression and metastasis, antibacterial autophagy, modulation of the immune system, and bone remodeling. The design, synthesis, and protein affinity evaluation of a set of C-3 substituted benzimidazole and quinoline d-galactal derivatives identified a d-galactal-benzimidazole hybrid as a selective ligand for the gale
Proper irrigation scheduling and agricultural water management require a precise estimation of crop water requirement. In practice, reference evapotranspiration (ETo) is firstly estimated, and used further to calculate the evapotranspiration of each crop. In this study, two new coupled models were developed for estimating daily ETo. Two optimization algorithms, the shuffled frog-leaping algorithm
Buildings account for a signifi cant proportion of the energy use thatgenerates greenhouse gases and consequently drives the ongoing climatechange. As the population of the world increases, the need for buildingsincreases, while the energy use needs to decrease. A reduction in energyuse and increased use of renewable energy are important measures forclimate change mitigation. A fi rst step in decr
In the next 24 years, the Malawian population is expected to double, a development that will inevitably affect access to land and land holding sizes. As access to land is already limited, securing food for the growing population will require policy shifts including the promotion of agricultural intensification. Malawi’s economy depends on the agricultural sector, and this paper addresses the gener
Copper from vehicles disc brakes is one main contributor of the total copper found in the environment. Therefore, the U.S. Environmental Protection Agency (EPA) and the automotive industries started the Copper-Free Brake Initiative. The pad friction material is essentially composed of a binder, fillers, reinforcing fibres and frictional additives. Copper and brass fibres are the most commonly used
Abstrakt. Ett etablerat MP2RAGE-protokoll för semikvantitativ strukturell hjärn-MRI överfördes frånen 7T MR-skanner till en annan leverantör med jämförbar hårdvara, men motsatt polaritet. På det härsystemet, kan skanningstiden reduceras från 11 till 8 minuter genom elliptisk k-space-sampling. Tre konfigurationerav radiofrekvens (RF) överföring jämfördes (enkelkanal med kvadraturen slits, två och åAbstract. An established MP2RAGE protocol for semi-quantitative structural brain MRI was transferred from one 7T MR scanner to that of another vendor featuring comparable hardware, but opposite polarity. On this system, the scan time could be reduced from 11 to 8 minutes by elliptical k-space sampling. Three configurations of radio-frequency (RF) transmission were compared (single channel with qu
Immunoglobulin A (IgA) is the dominant antibody isotype in the gut and has been shown to regulate microbiota. Mucosal IgA is also widely believed to prevent food allergens from penetrating the gut lining. Even though recent work has elucidated how bacteria-reactive IgA is induced, little is known about how IgA to food antigens is regulated. Although IgA is presumed to be induced in a healthy gut a
Abstract. In addition to the pheromone components (Z)‐5‐decenyl, (Z)‐7‐dodecenyl and (Z)‐9‐tetradecenyl acetate (Z5‐10:OAc, Z7‐12:OAc and Z9‐14:OAc), it has previously been shown that the sex pheromone gland of the turnip moth, Agrotis segetum (Lepidoptera: Noctuidae Schiff) contains 10:OAc, 12:OAc, Z5‐12:OAc, Z9‐12:OAc, 11–12:OAc, Z5‐14:OAc, Z7‐14:OAc and Z11‐16:OAc. To find out whether any of t
An established MP2RAGE protocol for semi-quantitative structural brain MRI was transferred from one 7T MR scanner to that of another vendor featuring comparable hardware, but opposite polarity. On this system, the scan time could be reduced from 11 to 8 minutes, mainly by elliptical k-space sampling. Three configurations of radio-frequency (RF) transmission were compared (single channel with quadr
As an influential publisher of miniature books in Europe during the late nineteenth and early twentieth century, David Bryce in Glasgow realized the profitable business of religious books and took use of the latest printing technologies to mass-produce small facsimiles of sacred texts in the world religions for a global market. This article presents some of the preserved letters from his colleague
This paper investigates potential factors that control the El Niño–Southern Oscillation (ENSO) Spring Persistence Barrier (SPB) strength in two different ENSO regimes and apply it to explain the ENSO SPB strength modulation after the 21st century. In a damped, noise-driven model, the theoretical solution of SPB strength illustrates that a weaker ENSO growth rate strengthens SPB. In the self-sustai
We present calculations on the atomic delay in photoionzation obtained with different combinations of linearly and circularly polarized light, and show how a tensor operator approach can be used to readily obtain results for any combination from a single calculation of the radial integrals. We find that for certain choices of polarization and detection geometry a single time-delay measurement is e
The search for mates and food is mediated by volatile chemicals. Insects sense food odorants and sex pheromones through odorant receptors (ORs) and pheromone receptors (PRs), which are expressed in olfactory sensory neurons. Molecular phylogenetics of ORs, informed by behavioral and functional data, generates sound hypotheses for the identification of semiochemicals driving olfactory behavior. Stu
Combustion of ammonia (NH3) as a carbon-free alternative fuel has been recently widely studied, with vast majority of the burning velocity data obtained at room temperature. In the present study, the laminar burning velocity SL of NH3/air mixtures has been measured at unburnt gas temperature Tu from 298 K to 448 K, covering equivalence ratios from 0.85 to 1.25 and at 1 atm using the heat flux meth
Background: Intensive care unit (ICU)-acquired delirium is frequent and associated with poor short- and long-term outcomes for patients in ICUs. It therefore constitutes a major healthcare problem. Despite limited evidence, haloperidol is the most frequently used pharmacological intervention against ICU-acquired delirium. Agents intervening against Delirium in the ICU (AID-ICU) is an international
Aim: To describe the experiences of peer learning in psychiatric inpatient settings during clinical placement of undergraduate nursing students and to highlight the possibility for peer learning in psychiatric outpatient settings. Design: A qualitative inductive design. Method: Questionnaires with 14 students and 12 preceptors in inpatient and outpatient care and interviews with one student and on
The paper presents research results from the Marie Skłodowska-Curie Innovative Training Network INFRASTAR in the field of reliability approaches for decision-making for wind turbines and bridges. This paper addresses the application of Bayesian decision analysis for installation of heating systems in wind turbine blades in cases where an ice detection system is already installed in order to allow
