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Weak convergence of the multivariate point process of upcrossings of several high levels by a stationary Gaussian process is established. The limit is a certain multivariate Poisson process. This result is then used to determine the joint asymptotic distribution of heights and locations of the highest local maxima over an increasing interval. The results are generalized to upcrossings and local ma
Aims: To examine whether the socio-economic determinants of alcohol use found in high-income university student settings are also true of Uganda. Design: Two cross-sectional surveys, conducted in 2005 and 2010, combined into a single dataset. Setting: Mbarara University of Science and Technology (MUST) in southwestern Uganda. Participants: 2,934 students (N in 2005 = 980; N in 2010 = 1,954). To
Echocardiography has a vital role for diagnosing and monitoring infectious endocarditis. The recently published Swedish guidelines for diagnosis and treatment of infectious endocarditis recommend overuse of transoesophageal echocardiography, which is not supported by the literature. The European Society of Cardiology presents a considerably more appropriate opinion.
Conclusion Sentinel lymph node biopsies (SLNBs) can be performed safely and with reasonable accuracy in HNM patients. The outcome provides important prognostic information concerning DFS and further treatment. However, one must recognize that SLNB is a multidisciplinary procedure with a learning curve for all. Objectives To evaluate efficacy of performing SLNBs in a series of consecutive patients
Rational, autonomous agents that are able to achieve their goals in dynamic, partially observable environments are the ultimate dream of Artificial Intelligence research since its beginning. The goal of this PhD thesis is to propose, develop and evaluate a framework well suited for creating intelligent agents that would be able to learn from experience, thus becoming more efficient at solving thei
A capillary filling microfluidic proteomic sample processing system has been realized in an automated set-up. Chip-integrated solid-phase extraction is performed in a 96-array format followed by sequential capillary action elution into a piezoelectric microdispenser and subsequent transfer to MALDI targets. Samples are eluted and deposited in volumes of 200–300 nl. The robotic system offers calibr
Antibodies to citrulline-modified proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear. To obtain insight into this question, a panel of mouse monoclonal antibodies was generated against a major triple helical collagen type II (CII) epitope (position 359-369; ARGLTGRPGDA) with or without arginines modified by cit
Study commissioned by BIL Sweden for the Committee for Producer Responsibility Review (M 2000:01) på uppdrag av BIL Sweden
Many problems concerning resource management in modern communication systems can be simplified to queueing models under Markovian assumptions. The computation of the optimal policy is however often hindered by the curse of dimensionality especially for models that support multiple traffic or job classes. The research focus naturally turns to computationally efficient bounds and high performance he
Thread-Level Speculation can be used to take advantage of multicore architectures for web applications. We have implemented Thread-Level Speculation in the state-of-the-art JavaScript engine V8 instead of using an interpreted JavaScript engine. We evaluate the implementation with the Chromium web browser on 15 popular web applications for 2, 4, and 8 cores. The results show that it is beneficial t
Newton-Raphson and Goldschmidt algorithms can be sped up by using variable latency hardware architectures for rounding division, square root and their reciprocals. A new approach based on a rounding method with remainder estimate calculated concurrently with the algorithm was proposed in [5]. This paper presents an study of the hardware implementation of this approach and shows that does not suppo
OBJECTIVE: People with disabilities find it harder to enter the labour market than people without disabilities and those with a mental illness are, in relation to people with other disabilities, employed at an essentially lower extent. Many are effectively helped by the vocational rehabilitation model Individual Placement and Support (IPS), but there are still many individuals left in undesired un
We report on fabrication and optical characterization of GaAs nanopillar (NP) arrays, obtained using a combination of low-cost mask generation by self-assembled silica particles (nanosphere lithography) and dry etching. Tapered structures (conical and frustum NP arrays) are fabricated by appropriate optimization of process parameters. Significant suppression of surface reflectance is observed for
Introduction: Knowledge of longitudinal progression in mild Alzheimer’s disease (AD) is required for the evaluation of disease-modifying therapies. Our aim was to observe the effects of long-term cholinesterase inhibitor (ChEI) therapy in mild AD patients in a routine clinical setting. Methods: This was a prospective, open-label, non-randomised, multicentre study of ChEI treatment (donepezil, riva
We have studied the influence of three different fullerene derivatives on the charge generation and recombination dynamics of polymer/fullerene bulk heterojunction (BHJ) solar cell blends. Charge generation in APFO3/[70]PCBM and APFO3/[60]PCBM is very similar and somewhat slower than charge generation in APFO3/[70]BTPF. This difference qualitatively matches the trend in free energy change of elect
A new class of chiral non-racemic gamma- and delta-amino alcohols based on bicyclo[2.2.1]heptane and bicyclo[2.2.2]octane have been synthesized and used as catalysts in the asymmetric diethylzinc addition to benzaldehyde. (C) 2008 Elsevier Ltd. All rights reserved.
This work compares the extent of linear response regions from standard time-resolving optical detectors for phosphor thermometry. Different types of photomultipliers (ordinary and time-gated) as well as an avalanche photodiode were tested and compared using the phosphorescence decay time of cadmium tungstate (CdWO4). Effects originating from incipient detector saturation are revealed as a change i
Systems based on bag-of-words models from image features collected at maxima of sparse interest point operators have been used successfully for both computer visual object and action recognition tasks. While the sparse, interest-point based approach to recognition is not inconsistent with visual processing in biological systems that operate in 'saccade and fixate' regimes, the methodology and emph
