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BACKGROUND: Diclofenac is widely used for postoperative analgesia but the perioperative safety of this drug is controversial because of its effect on platelet aggregation, which might increase blood loss. In a prospective investigator-blinded study the effects of diclofenac and paracetamol on pain and blood loss were compared in patients undergoing tonsillectomy. METHOD: Ninety patients were rando
In the European Union the Annexes of its chemical legislation (REACH) were revised and now clarify the technical data requirements for nanomaterials (NMs). These new provisions, effective from January 1, 2020, introduce requirements for manufacturers, importers and downstream users regarding registration and safety assessment of NMs. This study aims to assess the availability and suitability of me
We study the problem of decomposing a measured signal as a sum of decaying exponentials. There is a direct connection to sums of these types and positive semi-definite (PSD) Hankel matrices, where the rank of these matrices equals the number of exponentials. We propose to solve the identification problem by forming an optimization problem with a misfit function combined with a rank penalty functio
Background: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds. Methods: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy
Background: Antibiotics are commonly prescribed for outpatient management of cystitis. Previous evidence suggests that certain factors likely beyond the infection seem to influence the choice of antimicrobial treatment. However, studies on the specific antibiotic treatments for cystitis are lacking. This study aimed to explore the antibiotic treatments for cystitis using nationwide primary healthc
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive bronchoscopic procedure, well established as a diagnostic modality of first choice for diagnosis and staging of non-small cell lung cancer (NSCLC). The therapeutic decisions for advanced NSCLC require comprehensive profiling of actionable mutations, which is currently considered to be an essential
Background: GCA is a systemic vasculitis of the elderly, viewed by many as a disease with multiple and overlapping clinical phenotypes. Retrospective studies have shown differences in clinical presentation between these phenotypes. To reflect the heterogeneity of GCA and novel diagnostic methods, new classification criteria have been proposed. Methods: This is a retrospective study of newly diagno
This examination work is the final work in our education to become a Bachelor of Science in Mechanical Engineering by the University of Lund. The main purpose with this work has been to develop a new effective material handling system for TPPM AB in Lund since the existing system starts to become out of date. The future system that is going to be installed shall have the capacity to support all
Inflammation and subsequent endothelial dysfunction are main players in the vascular component of hypertension, and recent findings points to a key role of Sphingosine- 1-Phosphate and its signaling pathways in its pathophysiology. In neurodegenerative disorders such as Alzheimer’s disease, hypertension is the main modifiable risk factor, but insights regarding S1P receptor modulation in response
This Master Thesis aims to show an approach to the design of parallel robots,specifically the development of its kinematics. To do this, screw theory will be used, focusing on its theoretical bases and taking it later to practice. First, a theoretical definition of the inverse and forward kinematics of a parallel robot is carried out. Subsequently, algorithms are generated in Python that verify t
Aspects of Error Quantification and Evaluation in Digital Elevation Models for Glacier Surfaces This study explores methods to quantify and evaluate error in digital elevation models (DEMs) built from remotely sensed elevation data of the Hintereisferner glacier. A special focus lies on glacier surfaces because glaciers are often inaccessible for field observations but at the same time prone to m
In this thesis, a new probabilistic risk assessment tool for road tunnels has been verified and validated. The verification and validation were performed along with a literature review to find different key variables that affect the risk in a road tunnel and find out how these variables can be handled. Examples of variables are heat release, ventilation mode and factors within evacuation modelling
Using laser it is possible to measure the backscattered light from insects. The resulting signal can then be analysed in order to potentially determine the species of the insect. Estimating the fundamental wing beat frequency (FWBF) of insects is important in order do this classification of species, which is an area of research that has been explored previously. In this thesis, the relative phase
Due to increasing awareness and consumer demands it has become important for companies to develop an economical and environmentally sustainable alternative to traditional petroleum-based plastics. The transition from fossil material to bio based is important for the future of people and planet, still, how the transformation should be implemented is yet unknown. In this report, the possibilities of
The Large Hadron Collider (LHC) at CERN is undergoing a major upgrade to prepare for the High-Luminosity LHC. It will allow for many more particle collisions to occur. Some detectors that make up the LHC experiments must be replaced to withstand the harsher conditions. In particular, the inner tracking detector (ID) of the ATLAS experiment will be replaced by the new Inner Tracker (ITk). Every co
Due to increasing global energy demands and a need to move away from non-renewable energy sources, green hydrogen is now being considered as a possible replacement for fossil-based energy sources. Especially in “hard-to-abate” sectors, such as steel and petrochemical production, and long-distance transport, where the change to renewable electricity is more difficult. Green hydrogen is produced thr
