Filetype
We report a flow-injection biosensor system with a capacitive transducer for assay and quality control of human immunoglobulin G (hIgG). The sensing platform is based on self-assembled monolayers (SAMs) of carboxylic acid terminated alkyl-thiols with covalently attached concanavalin A. The electrochemical characteristics of the sensor surface were assessed by cyclic voltammetry using a permeable r
By utilizing flow-controlled PLL-g-PEG and PLL-g-PEGbiotin modification of predefined regions of a poly-(dimethylsiloxane) (PDMS) micro-fluidic device, with an intentionally chosen large (similar to 1 cm(2)) internal surface area, we report rapid (10 min), highly localized (6 x 10(-6) cm(2)), and specific surface-based protein capture from a sample volume (100 mu L) containing a low amount of prot
Using exact dispersion relations for electromagnetic wave propagation in layered, periodic media, consisting of two phases, we derive explicit asymptotic solutions for small wavenumbers. These solutions are compared to the numerical solutions of the exact dispersion relations, and applications to homogenization problems are discussed. The results can be used as test cases for homogenization techni
A fragment-based development of 3C-triazol-1-yl-O-galactopyranosyl aldoximes led to the discovery of highly selective and high affinity (K(d) down to 11 microm) small monosaccharide based inhibitors of galectin-3. Galectin-7, 8 N-terminal CRD, and 9 N-terminal CRD bound the inhibitors only weakly. The galectin-3 selectivity was hypothesized to stem from interaction of the aldoxime moiety with a si
Parks, remnants of natural habitats and other green areas are important for preserving biodiversity in urban areas. Here, we investigate the relative importance of habitat type and connectivity for butterfly species richness in the city of Malmo, Sweden. Further, we compare species richness and composition in the urban habitats with that in the surrounding agricultural landscape using previously p
We have used density functional methods to calculate fully relaxed potential energy curves of the seven lowest electronic states during the binding of O-2 to a realistic model of ferrous deoxyheme. Beyond a Fe-O distance of similar to 2.5 Angstrom, we find a broad crossing region with five electronic states within 15 kJ/mol. The almost parallel surfaces strongly facilitate spin inversion, which is
BACKGROUND: Diclofenac is widely used for postoperative analgesia but the perioperative safety of this drug is controversial because of its effect on platelet aggregation, which might increase blood loss. In a prospective investigator-blinded study the effects of diclofenac and paracetamol on pain and blood loss were compared in patients undergoing tonsillectomy. METHOD: Ninety patients were rando
We present a data-driven proof of concept model capable of reproducing expected counterparty credit exposures from market and trade data. The model has its greatest advantages in quick single-contract exposure evaluations that could be used in front office xVA solutions. The data was generated using short rates from the Hull-White One-Factor model. The best performance was obtained from a GRU neur
With the ambition to contribute to a sustainable development, this project started with aim to recycle fiber boards. The idea behind the project is to take lose fibers that come from waste product or simply just worn out fiber boards, and make them into new fiber boards. In order to achieve this, a binder is needed to hold the boards together. The aim of this thesis was to evaluate different binde
The food industry is facing challenges in responding to the climate crisis, and research highlights the potential of using Business Intelligence & Analytics for organizations sustainability efforts. The aim of this study is to holistically map through the affordance lens, what capabilities organizations in the food industry may potentially gain by using BI&A for sustainability. The study i
The purpose of the thesis is to design a new antenna system and to verify its link performance in 5G FR2 mmWave frequency for handheld devices to enable cellular communication. The main objective is to design an antenna primarily at 28GHz and 39GHz to enhance spectrum efficiency, along with improved transmission data rates, enabling new cases like Augmented Reality (AR), Virtual Reality (VR) and
Research conducted on industrial symbiosis often brings up the importance of trust and collaboration related constraints and enablers if inter-organizational efforts are to be pursued. This is also found in literature related specifically to Sweden and its agri-food sector. There are limited examples of collecting empirical evidence on trust in relation to IS and even less so with a focus on SMEs.
Spallation sources such as European Spallation Source (ESS) produces neutrons by bombarding high-energy protons onto the target wheel. To determine the location of the proton beam a Proton Beam Imaging (PBI) system will be installed. The PBI system at ESS relies on the properties of a luminescent coating that is sprayed onto the target wheel and the proton beam window. In this study, luminescent m
There is an extensive expansion of fiber infrastructure for high-speed broadband networks in Sweden, and Landskrona municipality is one of the leading examples. Owing to the superior capabilities of a fiber based network, a number of digital welfare services can be provided directly to residents and companies of the municipality. Social care is an example of a welfare service that can utilize the
Deep learning is a machine learning technique inspired by the biological nervous system. The method has been used more and more over the last decades. Within this thesis, convolutional neural networks (CNN:s) are used for Gleason classification of prostate cancer in histopathological images. The data that has been used consists of digitalized microscopic images of prostate biopsies stained with ha
Flow cytometry is a versatile tool for monitoring a microbial population at a single-cell level. Multiple parameters can be monitored based on the users’ requirements through the utilization of different dyes, biosensors etc., and the use of FCM for on-line measurements during fed-batch cultivations has the potential to be used for precise process control. This project consisted of the development
Under de senaste åren har stora resurser lagts på forskning kring utvecklingen av biomaterial för ersättning av fossil-baserade material. Förpackningsindustrin i synnerhet är en sektor känd för att generera enorma mängder fast avfall, med produkter som inte sällan har betydligt kortare livslängd än sina materialkomponenter. Polylaktid (PLA) är en mångsidig biopolymer som används kommersiellt föIn recent years, large efforts have been put into the research of biomaterial synthesis for the replacement of fossil-based materials. Particularly in the packaging industry, a sector responsible for generating enormous amount of solid waste in which products have a considerably shorter life span than their material components. Polylactic acid (PLA) is a versatile, commercial biopolymer used fo
The purpose of this paper is to predict the cost-effectiveness of a preventive health care project based on physical exercise that will take place at Medicon Village, Lund, in the fall of 2016. Data from the Health Survey for England is used to develop an empirical model with individual fixed effects that estimates the relationship between physical exercise and psychological well-being. The freque
Thymidine kinase 1 from tomato (ToTK1) is a newly discovered deoxyribonucleoside kinase (dNK) that has been subject to study due to its in vitro and in vivo properties making it an interesting suicide gene candidate for the treatment of brain tumors. The ToTK1 phosphorylates the nucleoside analogue 3-azido-2,3-dideoxythymidine (azidothymidine, AZT) equally well as its natural substrate thymidine (
