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Phenotypic modulation of smooth muscle cells (SMCs) plays a key role in vascular disease, including atherosclerosis. Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown. Recent reports suggest that specific microRNAs (miRNAs) are involved in SMC differentiation and vascular disease but the global role of miRNAs in p
Popular Abstract in Swedish Jätteplaneterna, Jupiter, Saturnus, Uranus och Neptunus, är de största planeterna i solsystemet. De ligger långt från solen och har alla betydande gasatmosfärer, upp emot hundra gånger mer massiva än hela jorden. Tack vare de tjocka gashöljena, med en sammansättning som liknar solens, kan man förstå att jätteplaneterna bildades i en gasskiva. Denna skiva kallas för solGiant planets form embedded in a protoplanetary disc around a young star. Close to the midplane a large fraction of the available mass in solids is found in particles of cm to dm in size, which drift towards the star due to friction with the surrounding gas. In paper I, II, III we describe a novel theory that explains how embryos, planetesimals larger than ~1000 km, grow efficiently by sweeping up
The pre-Talpha (pTalpha[?]) gene encodes a protein that forms the pre-TCR together with the newly expressed TCR beta chain during a defined stage of early T cell development. The restricted expression of this gene has been suggested to depend on a promoter and an enhancer element containing E boxes, which are potential binding sites for basic helix-loop-helix (bHLH) proteins. We here report that i
BACKGROUND: Acute dyspnea affects a large heterogeneous patient group with high mortality and readmission rates.PURPOSE: To investigate if cardiometabolic biomarkers and clinical characteristics predict readmission and death in patients hospitalized for acute dyspnea.METHODS: 65 dyspnea patients at a general internal medicine ward were followed for six months. The combined endpoint was readmission
The ionizable-lipid component of RNA-containing nanoparticles controls the pH-dependent behavior necessary for an efficient delivery of the cargo - the so-called endosomal escape. However, it is still an empirical exercise to identify optimally performing lipids. Here, we study two well-known ionizable lipids, DLin-MC3-DMA and DLin-DMA using a combination of experiments, multiscale computer simula
An interdisciplinary symposium on the functions and aesthetics of sound in museums 2019-04-09 Sound Environment Centre hosted the interdisciplinary symposium on the functions and aesthetics of sound in museums. Sounding MuseumsWithin recent years sound has played a more and more prominent role in museums. Fine art galleries now integrate sound as part of the aesthetic expressions exhibited meanwhi
https://www.lmc.lu.se/aktiviteter/aktiviteter-2019/sounding-museums - 2026-07-07
Elephant Moraine (EET) 96029 is a CM carbonaceous chondrite regolith breccia with evidence for unusually mild aqueous alteration, a later phase of heating and terrestrial weathering. The presence of phyllosilicates and carbonates within chondrules and the fine-grained matrix indicates that this meteorite was aqueously altered in its parent body. Features showing that water-mediated processing was
SynopsisReduction of gold(III) complexes by thiocyanate takes place via rapid substitutions at gold(III), followed by intramolecular, slower reductive elimination through attack by outer-sphere thiocyanate. A transition state with an S−S interaction between attacking and coordinated thiocyanate is suggested for the redox process.AbstractAbstract ImageKinetics for reactions between thiocyanate and
This contribution deals with a specific ritual expression among the Sámi, the bear grave. Brown bears were sacred in the Sámi society. They were hunted, killed, and then consumed during a feast. All bones of the killed bear were afterwards collected and carefully buried. At present, in the Swedish part of Sápmi, we have evidence of definite Sámi bear graves going back in time for one thousand year
