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Vascular smooth muscle phenotype is regulated by environmental factors, such as mechanical forces, which exert effects on signaling to differentiation and growth. We used the mouse portal vein in organ culture to investigate stretch-dependent activation of Akt, extracellular regulated protein kinase (ERK) and focal adhesion kinase (FAK), which have been suggested to be involved in the regulation o
A number of optically pure 1,3-diols have been synthesized and used as catalysts in the asymmetric addition of diethylzinc to aromatic aldehydes. Enantiomeric excesses of up to 92% of (R)-1-phenylpropan-1-ol were obtained with anisylbicyclo[2.2.2] octanediol (14) as a catalyst. Using 2-picolylbicyclo[ 2.2.2] ocatanediol (16) as the catalyst resulted in a reversal of the stereoselectivity, yielding
We present new synthetic broad-band photometric colors for late-type giants based on synthetic spectra calculated with the PHOENIX model atmosphere code. The grid covers effective temperatures T-eff = 3000... 5000 K, gravities log g = - 0.5... + 3.5, and metallicities [M/H] = + 0.5... - 4.0. We show that individual broad-band photometric colors are strongly affected by model parameters such as mol
Screening women for lower genital tract infection with Chlamydia trachomatis is important in the prevention of pelvic inflammatory disease, ectopic pregnancy and infertility. This systematic review aims to state clearly which of the available diagnostic tests for the detection of C. trachomatis would be most effective in terms of clinical effectiveness. The review included all studies published fr
This paper describes a methodology for measuring theological flow properties in-line, in real-time, based on simultaneous measurements of velocity profiles using an ultrasound velocity profiling (UVP) technique with pressure difference (PD) technology. The methodology allows measurements that are rapid, non-destructive and non-invasive and has several advantages over methods presented previously.
We examine the near-field optical properties of multilayered metal core-shell sphere nanostructures by extending the Mie theory, and demonstrate that the local-field enhancement can be increased by adding new metal shells. A local intensity enhancement of more than 10(5) times can be obtained in the cavity between the Ag core and the innermost Ag shell for proper configurations of multilayered Ag
The Oxford-12 Item Knee Score is a recently developed and validated patient-completed outcome measure designed specifically for use with knee arthroplasty in the United Kingdom. We have translated this questionnaire into Swedish and tested the validity and reliability of the translated version in a cross-sectional study by a postal survey to 1,200 randomly selected patients from the Swedish Knee A
Carrier frequency offset (CFO) synchronization is a crucial issue in the implementation of orthogonal frequency division multiplexing (OFDM) systems. Since current technology tends to implement different standards in the same wireless device, a common frequency synchronization structure is desirable. Knowledge of the physical frame and performance and cost system requirements are needed to choose
This paper introduces a two-dimensional extension of the well established Rietveld refinement method for modeling neutron time-of-flight powder diffraction data. The novel approach takes into account the variation of two parameters, diffraction angle 2θ and wavelength λ, to optimally adapt to the varying resolution function in diffraction experiments. By doing so, the refinement against angular- a
BACKGROUND: The objective of this study was to assess, in a large data set from Swedish Medical Health Registries, whether maternal obesity and maternal morbid obesity were associated with an increased risk for various structural birth defects. METHODS: The study population consisted of 1,049,582 infants born in Sweden from January 1, 1995, through December 31, 2007, with known maternal weight and
Childhood and adolescence are critical periods of neural development and physical growth. The malnutrition and related medical complications resulting from eating disorders such as anorexia nervosa (AN), bulimia nervosa (BN) and eating disorder not otherwise specified may have more severe and potentially more protracted consequences during youth than during other age periods. The consensus opinion
Primary and backup paths in MPLS fast reroute (FRR) may be established as shortest paths according to the administrative link costs of the IP control plane, or as explicitly calculated arbitrary paths. In both cases, the path layout can be optimized so that the maximum link utilization for a specific traffic matrix and for a set of considered failure scenarios is minimized. In this paper, we propo
OBJECTIVES: To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. METHODS: A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiograph
We present a summary of late Paleoproterozoic to Neoproterozoic mafic magmatism in the Siberian craton, including recently published U-Pb and Ar-40-Ar-39 dates. These new precise ages suggest that at least some of the previously published K-Ar ages of Siberian mafic bodies should be ignored. The time-space geochronological chart, or the 'barcode' of mafic magmatic events shows significant differen
Detailed (222)radon (Rn-222) flux maps are an essential pre-requisite for the use of radon in atmospheric transport studies. Here we present a high-resolution Rn-222 flux map for Europe, based on a parameterization of Rn-222 production and transport in the soil. The Rn-222 exhalation rate is parameterized based on soil properties, uranium content, and modelled soil moisture from two different land
Biofuels for transport are attracting considerable support from the European Union. However, the complexity of the biofuels industry and the diversity of actors create significant challenges for policy-making and governance. This paper explores the role of governance in the development of the biofuels industry in Europe focusing on Sweden and the UK. The purpose of this paper is to investigate the
By reducing the cadmium (Cd(2+)) content in biomass used for bio-based products such as biogas, a less toxic bio-based fertilizer can be obtained. In this work, we demonstrate how a macroporous polymer can support titanate nanotubes, and we take advantage of its known selective adsorption behavior towards Cd(2+) in an adsorption process from real nutrient-rich process water from hydrolysis of seaw
