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We randomised 46 newly diagnosed patients with chronic myeloid leukaemia (median age 56) to receive dasatinib 100mg QD or imatinib 400mg QD and report outcome as an intention-to-treat analysis with 36months follow-up. Early cytogenetic and molecular responses were superior in the dasatinib group, with a tendency that imatinib patients caught up with time. For instance, MR3.0 was reached at 3months

Indications exist in the scientific literature that infection with human herpes family viruses may contribute to the pathogenesis of neuroblastoma (NB). However, systematic investigations regarding viral presence in NB cells have been scarcely reported. Here, the presence of DNA from Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) was assessed by PCR in 12 NBs, supplemented with RNA in s

Background:Three prospective studies have evaluated the association between dietary acrylamide intake and endometrial cancer (EC) risk with inconsistent results. The objective of this study was to evaluate the association between acrylamide intake and EC risk: for overall EC, for type-I EC, and in never smokers and never users of oral contraceptives (OCs). Smoking is a source of acrylamide, and OC

Abstract Objective. Prostate cancer antigen 3 in urine (uPCA3) has been shown to perform better than total prostate-specific antigen in serum (tPSA) to predict prostate cancer (PCa) detection. The aim of this study was to validate the diagnostic precision of uPCA3 in a mixed set of patients with no previous history of PCa, including patients with previous negative biopsies. Material and methods. T

Breast tumors from BRCA1 germ line mutation carriers typically exhibit features of the basal-like molecular subtype. However, the specific genes recurrently mutated as a consequence of BRCA1 dysfunction have not been fully elucidated. In this study, we utilized gene expression profiling to molecularly subtype 577 breast tumors, including 72 breast tumors from BRCA1/2 mutation carriers. Focusing on

Popular Abstract in Swedish Avhandlingen innehåller tre empiriska studier som analyserar hur livsmedelsmarknaden påverkas av åtgärder för att fördjupa den europeiska ekonomiska integrationen. Fokus är på det svenska EU-medlemskap och det kontinuerliga arbetet med att harmonisera livsmedelslagstiftningen. Det senare har stor relevans för livsmedelsmarknaden eftersom det har funnits och fortfarande This thesis consists of three papers, all of which deal with the effects of deepening European integration on the food and beverage industry and market. The focus is on the period after Swedish EU membership in 1995. The last two papers use firm data and focus on the Swedish food and beverage industry, an industry which is an interesting case study as it was considered to be protected from foreign

Monitoring of condylomas is an early evidence of population effectiveness of human papillomavirus (HPV) vaccination programs. If reporting could include HPV typing, the contribution by vaccine HPV types to condyloma burden could be monitored.

BACKGROUND: Breast cancer detected by screening has an unexplained prognostic advantage beyond stage shift compared with cancers detected clinically. The aim was to investigate biological factors in invasive breast cancer, with reference to mode of detection and rate of death from breast cancer. METHODS: Histology, oestrogen receptor α and β, progesterone receptor, human epidermal growth factor

The fact that breast cancer patients with local or distal dissemination exhibit decreased survival, promotes a search for novel mechanisms to suppress such tumor progression. Here we have determined the expression of pro-inflammatory cysteinyl leukotriene receptors (CysLTRs) in breast tumor tissue and their signaling effect on breast cancer cell functions related to tumor progression. Patients wit

During development, hematopoietic stem cells (HSCs) undergo a rapid expansion in the fetal liver (FL) before settling in the adult bone marrow. We recently reported that proliferating adult HSCs are vulnerable to ER stress caused by accumulation of mis-folded proteins. Here, we find that FL-HSCs, despite an increased protein synthesis rate and a requirement for protein folding, do not upregulate E

Androgen receptor (AR) is expressed in all stages of prostate cancer progression, including in castration-resistant tumors. Eliminating AR function continues to represent a focus of therapeutic investigation, but AR regulatory mechanisms remain poorly understood. To systematically characterize mechanisms involving microRNAs (miRNAs), we conducted a gain-of function screen of 1129 miRNA molecules i

The aim of this investigation was to assess the Ku70/Ku80 complex as a potential target for antibody imaging of prostate cancer. We evaluated the in vivo and ex vivo tumor targeting and biodistribution of the (111)In-labeled human internalizing antibody, INCA-X ((111)In-DTPA-INCA-X antibody), in NMRI-nude mice bearing human PC-3, PC-3M-Lu2 or DU145 xenografts. DTPA-conjugated, non-labeled antibody

Student handbook 2022 WEB 1 GRADUATE SCHOOL STUDENT HANDBOOK 2022-23 Version 1.0 August 2022 1 Welcome 1 Letter from the Director of Studies 3 About 4 Lund University 5 The Faculty of Social Sciences 5 Graduate School 5 Contact information 7 Communication channels 8 Studying at Graduate School 9 Our Master’s programmes 10 Term 1 10 Term 2 12 Term 3 13 Term 4 14 Thesis preparation track 15 Pedagogi

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2022-08/Student%20handbook%202022.pdf - 2026-06-05

Adato användarmanual Sida 0. Miljödata AB Ronnebygatan 46 0455 – 33 35 30 BG: 5504-4325 Org. nr: 556324-4036 371 33 Karlskrona miljodata.se Författare: Tova Westin PG: 17141-3 Adato användarmanual Version 3.7.3 Senast uppdaterad: 2025-12-03 Adato användarmanual Sida 1. Miljödata AB Ronnebygatan 46 0455 – 33 35 30 BG: 5504-4325 Org. nr: 556324-4036 371 33 Karlskrona miljodata.se Författare: Tova We

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-02/Adato%203.7.3%20anv%C3%A4ndarmanual%20(1).pdf - 2026-06-05

7,3 miljoner flickor under 18 år föder varje år. En av tre flickor i länder med låg- eller medelinkomst kommer att gifta sig före 18 års ålder. Detta är en kränkning mot flickor och deras mänskliga rättigheter. United Nations Population Fund, UNFPA arbetar med att stärka kvinnors och unga människors möjligheter att leva ett hälsosammare och ett mer produktivt liv. Med detta i åtanke är syftet att

LUNDS UNIVERSITET SAMHÄLLS­ VETENSKAPLIGA FAKULTETEN PROTOKOLL 2020-06-05 1 Diarienummer Graduate School Nämnden för Graduate School, 2020-06-05 Närvarande Ledamöter Mikael Sundström Karin Steen Jakob Gustavsson Marta Kolankiewicz Rola EI-Husseini Annika Bergman Rosamond Shai Mulinari Christopher Swader Leili Laanemets Anne Jerneck Övriga Lucie Larssonova Frank Schreier Yagmur Yilmaz Buleza Emerll

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2020-08/Protokoll%20Na%CC%88mnden%20fo%CC%88r%20GS%20200605.pdf - 2026-06-05

Microsoft Word - PARTICLE PHYSICS.docx 1 PARTICLE PHYSICS AND COSMOLOGY Lars Gislén Hans-Uno Bengtsson Gösta Gustafson Department of Theoretical Physics, Lund University Spring 2001 2 3 Chapter l. Quarks, leptons and forces The fundamental particles of matter are quarks and leptons. They can be arranged in three families or generations according to the following scheme: Electric charge u d ⎛ ⎝⎜ ⎞

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2025-01/particle-physics-cosmology.pdf - 2026-06-05

RÖSTLÄNGD VID VAL AV LEDAMÖTER TILL UTBILDNINGSNÄMNDER VID MHM # Efternamn Förnamn Orgenhet Befattning 1 Albertsson Fredrik 458503 Musiker- o kyrkomusikerutbildn timlärare 2 Almgren Seki Beniko 458503 Musiker- o kyrkomusikerutbildn universitetsadjunkt 3 Andersson Carl-Axel 458502 Musiklärarutbildningen universitetslektor 4 Andersson iHans 458502 Musiklärarutbildningen universitetslektor 5 Andersso

https://www.mhm.lu.se/internt/sites/mhm.lu.se.internt/files/2023-09/Ro%CC%88stla%CC%88ngd_UN_faststa%CC%88lld_korr_u.pdf - 2026-06-05

LL_SMAA30_rev_170901 Litteraturlista för Service management: Grundkurs, 30 hp (SMAA30) Litteraturlistan är fastställd av styrelsen för institutionen för service management och tjänstevetenskap 2017-06-20, reviderad 2017-09-01. Litteraturlistan börjar gälla 2017-08-01 resp 2017-10-01. Delkurs 1 Andersson, Göran & Greve, Jan. (2016). Kalkyl och budget - grundläggande om kalkylering och budgetering.

https://www.ses.lu.se/sites/ses.lu.se/files/ll_smaa30_rev_170901.pdf - 2026-06-05