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Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of biologic responders in adults with severe asthma and investigate patient characteristics associated with biologic response. Methods: This was a longitudinal cohort study using d
This is the second article in the psychological elements of palliative care (PEPC) series. This series focuses on how key concepts from psychotherapy can be used in the context of palliative care to improve communication and fine tune palliative care interventions. In this article, we introduce two foundational concepts: frame and formulation. The frame is the context in which care is delivered; i
Ex-situ Raman spectroscopy is a well-established method for the structural characterization of soot but necessitates a sampling step before analysis is made. This work studied the potential to perform Raman spectroscopic measurements of soot directly in the combustion exhaust gases, i.e., online Raman measurements. Two types of soot were produced from a Mini-CAST soot generator, one immature with
Cellular-based localization and sensing pave the way for a variety ofapplications across various domains, ranging from autonomous driv-ing to emergency care and intelligent traffic management. Althoughtraditional methods have been effective, they still face challenges such as therequirement for highly accurate models and the inherent complexity of thealgorithms. This thesis explores the potential
High-order harmonic generation (HHG) supplies extreme ultraviolet (XUV) radiation with attosecond pulse duration for a wide variety of applications from fundamental research to industry. As HHG is a very inefficient process, enhancing the XUV flux is of great interest. Hereby, either the HHG process itself or the laser which is the primary driver of HHG can be optimized.Currently, the technology i
Unmanned aerial vehicles (UAVs) have been widely used in both military and civilian applications, where a stable communication link is vital for safe flight control and robust data transmission. To develop a reliable UAV communication system, it is necessary to deeply understand the UAV channel characteristics and establish accurate channel models. Channel sounding is the most effective way to obt
Electrons from a laser wakefield accelerator have a limited energy gain due to dephasing and are prone to emittance growth, causing a large divergence. In this paper, we experimentally show that adjusting the plasma density profile can address both issues. Shock-assisted ionisation injection is used to produce 100 MeV quasi-monoenergetic electron bunches in the primary part of the accelerator. Dow
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of vestibular stimulation compared to standard care or non-vestibular stimulation for physical and neurological development in preterm infants. To assess whether the effects of vestibular stimulation differ according to gestational age at birth; the type, frequency,
for clarinet, bassoon, horn and trumpetImpossible colors is not a hypothesis, but rather more hyperbole. In this musical piece "impossible colors" refer to illusions of timbre in sound, not vision. Impossible colors are colors that we do not normally see; that some fictional colors are beyond the functional perceptual space of humans. Some theories looking at forbidden colors, borrowed from color
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of infant positioning, nesting, and swaddling for promoting development and preventing morbidity in preterm infants.
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the benefits and harms of multisensory stimulation compared to any single sensory intervention or standard care for physical and neurological development in preterm infants.
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To evaluate the benefits and harms of olfactory stimulation with different odorants in the NICU for promoting development and preventing morbidity in preterm infants.
In this paper we argue that comprehensive and systematic parental education has the potential to equip young adults with the necessary information for the responsible exercise of their autonomy in choices about reproduction and parenting. Education can allow young adults to acquire largely accurate beliefs about reproduction and parenting and about the implications of their reproductive and parent
The direct reaction between carbohydrates and CO2 has recently attracted attention in the context of cellulose dissolution and derivatization as well as carbon capture applications. We have directly demonstrated the formation of cellulose carbonate upon the introduction of CO2 into a non-aqueous cellulose solution by nuclear magnetic resonance spectroscopy. Comparison of the observed spectra with
In this paper, a measurement campaign for massive multiple-input multiple-output (MIMO) channel characterization in both line-of-sight (LoS) and non-LoS outdoor environments is introduced. The measurements are conducted at the center frequency of 15 GHz with a bandwidth of 4 GHz. A virtual 40× 40 planar antenna array formed by stepping a vertically-polarized bi-conical omni-directional antenna (OD
In this contribution, a measurement campaign for high- speed-train (HST) channel is introduced where the down- link signals of in-service Long Time Evolution-Advanced (LTE-A) network deployed along the HST railway between Beijing to Shanghai are acquired. Channel impulse responses (CIRs) are extracted from received signals, and concatenated power delay profiles (CPDPs) are illustrated. According t
In this paper, a recently conducted measurement campaign for vehicle-to-vehicle (V2V) propagation channel characterization is introduced. Two vehicles carrying a transmitter and a receiver, respectively, have been driven along an eight-lane road with heavy traffic. The measurement was conducted with 100 MHz signal bandwidth at a carrier frequency of 5.9 GHz. Channels are observed consisting of two
We present Bioconda (https://bioconda.github.io), a distribution of bioinformatics software for the lightweight, multi-platform and language-agnostic package manager Conda. Currently, Bioconda offers a collection of over 3000 software packages, which is continuously maintained, updated, and extended by a growing global community of more than 200 contributors. Bioconda improves analysis reproducibi
