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Popular Abstract in Swedish Affärsklimatet för dagens energimarknad har varit händelserik de senaste två decennierna med introduktaion av den avreglerade elmarknaden och den ökade vikten av miljöfrågor vid design och inköp av energirelaterade anläggningar. Detta har bidragit med krav om nya analyskriterier, vilka inte bara påverkar den tekniska utformningen av komponenter och system, utan även tilThe business climate of the energy market has been eventful over the last two decades, particularly with the introduction of the deregulated electricity market and promotion of environmental issues. This has subsequently lead to new analysis criteria, influencing both technology requirements and production costs. To be able to manage all the questions that have arisen from this the knowledge of th

Popular Abstract in Swedish Tillväxthormon (GH) insöndras stötvis från hypofysen. Insöndringen är som högst nattetid, och de högsta nivåerna ses under puberteten för att därefter avta succecivt med ökande ålder. En av de vanligaste orsakerna till brist på GH är godartade tumörer i hypofys och hypofysnära områden där även behandling med kirurgi och strålbehandling kan bidra till hypofysinsufficiensIn childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. No significant improvement in cardiac systolic function or GFR, except for a

The French Safety and Appropriateness of Growth Hormone treatments in Europe (SAGhE) cohort has raised concern of increased mortality risk during follow-up into adulthood in certain patients who had received growth hormone (GH) treatment during childhood. The Hypopituitary Control and Complications Study monitored mortality and morbidity of adult GH-deficient patients including those with childhoo

This article examines the foundation of β-cell failure in type 2 diabetes (T2D) and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment.RESEARCH DESIGN AND METHODS: A group of experts participated in a conference on 14-16 October 2013 cosponsored by the Endocrine Society and the American Diabetes Association. A writing group prepared t

Background. Oestrogen receptor (ER) status is important for the choice of systemic treatment of breast cancer patients. However, most data from randomised trials on the effect of adjuvant endocrine therapy according to ER status are based on the cytosol methods. Comparisons with immunohistochemical methods have given similar results. The aim of the present study was to examine whether different ER

BACKGROUND: Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH: An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A new system was developed to grade the overall quality of the evidenc

This study evaluated a technique to allow the long-term monitoring of individual fishes of known sex in the wild using sex confirmation in close proximity to the reproductive period combined with individual tagging. Hundreds of partially migratory roach Rutilus rutilus were tagged with passive integrated transponders (PIT) following sex determination in spring and various performance measures were

As new technologies emerge such as wearables, it opens up for new challenges, especially related to security and privacy. One such recent technology is smart glasses. The use of glasses introduces security and privacy concerns for the general public but also for the user itself. In this paper we present ongoing theoretical work which focus on privacy of the user during authentication. We propose a

In order to study the effects of increasing age on the human skeletal muscle, cross-sections (15 micron) of autopsied whole vastus lateralis muscle from 43 previously physically healthy men between 15 and 83 years of age were prepared and examined. The data obtained on muscle area, total number, size, proportion and distribution of type 1 (slow-twitch) and type 2 (fast-twitch) fibers were analysed

Objective. To follow patients with fibromyalgia six and 24 months after they finished a six-month treatment programme. The programme comprised pool exercise therapy, adjusted to the patients' limitations, and education based on their health problems. Methods. Twenty-six patients were examined six and 24 months after the completion of the treatment programme with the Fibromyalgia Impact Questionnai

In the microelectronics industry, gold electrodes on silicon dioxide are produced using an adhesive layer of chromium or titanium. This method is applicable whenever a dry environment is present. However, when such an electrode is exposed to an electrolyte a galvanic cell is formed and the less noble metal will dissolve and eventually destroy the electrode. We describe here how a monolayer of merc

This article proceeds from the argument that various forces of globalization have resulted in increased dislocation and uncertainty for many people in the world. Religion and nationalism, compared to most other identity constructions, are viewed as particularly relevant organizing principles at a time when modern society is making increasing demands on individuals. In comparison to much constructi

Climate change researchers argue that a residual domain exists beyond the limits of adaptation to prevent deleterious climate change impacts: this has been labeled as “loss and damage.” Over the last 8 years, there has been significant growth in loss and damage scholarship thus making it imperative to take stock of what we know already and directions for future research. We undertook a quantitativ

Developing organisms typically mature earlier and at larger sizes in favorable growth conditions, while in rarer cases, maturity is delayed. The rarer reaction norm is easily accommodated by general life history models, whereas the common pattern is not. Theory suggests that a solution to this paradox lies in the existence of critical size thresholds at which maturation or metamorphosis can commen

Industrial cyber-physical system products interleave hardware, software, and communication components. System complexity is increasing simultaneously with increased demands on quality and shortened time-to-market. To effectively support the development of such systems, we present languages and tools for comprehensive integrated model-based development that cover major phases such as requirement an

The demand for large-scale and long-term information on tree growth is increasing rapidly as environmental change research strives to quantify and forecast the impacts of continued warming on forest ecosystems. This demand, combined with the now quasi-global availability of tree-ring observations, has inspired researchers to compile large tree-ring networks to address continental or even global-sc

In Classical Athens, being at war was more common than peace. The military expenditures were correspondingly large. The main puzzle, however, is not financial, but where the Athenians found the multitude of rowers needed for their ships. It was not until the end of the Peloponnesian War that there were good reasons to use slaves as rowers. The Spartan occupation of Decelea in 413 BCE had profound

Let NDTIME(f(n),g(n)) denote the class of problems solvable in O(g(n)) time by a multi-tape Turing machine using an f(n)-bit non-deterministic oracle, and let DTIME(g(n)) = NDTIME(0, g(n)). We show that if the all-pairs shortest paths problem (APSP) for directed graphs with N vertices and integer edge weights within a super-exponential range { -2Nk+o(1),.,2Nk+o(1)}, k≥1 does not admit a truly subc