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α-Synuclein (α-syn), a small protein that has the intrinsic propensity to aggregate, is implicated in several neurodegenerative diseases including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), which are collectively known as synucleinopathies. Genetic, pathological, biochemical, and animal modeling studies provided compelling evidence that α-syn aggr

Since the late 1980s, our group has examined the effects of radiofrequency electromagnetic fields (RF-EMF), including pulse-modulated waves of the type emitted by mobile phones, upon the blood-brain barrier. In more than 2,000 rats, we have repeatedly demonstrated a passage of the rats' own albumin from the blood through the brain capillaries into the surrounding brain parenchyma at SAR values dow

While several rating scales reliably and cost-effectively assess behavioral executive functioning (EF) in youths with neurodevelopmental disorders (NDDs), questions remain about the impact of comorbidities and dual NDDs on EF as measured by these scales in clinical samples. This study compared behavioral EF profiles among youths with NDDs, both with and without psychiatric comorbidities, non-NDDs

A new method for extracting seasonality information from time-series of satellite sensor data is presented. The method is based on nonlinear least squares fits of asymmetric Gaussian model functions to the time-series. The smooth model functions are then used for defining key seasonality parameters, such as the number of growing seasons, the beginning and end of the seasons, and the rates of growt

Background. The conventional treatment for poststernotomy mediastinitis usually involves surgical revision, closed irrigation, or reconstruction with omentum or pectoral muscle flaps. Recently, vacuum-assisted closure has been successfully used in poststernotomy mediastinitis. The aim of the present study was to compare the clinical outcome and survival in 101 patients undergoing vacuum-assisted c

Popular Abstract in Swedish Every breath you take – Every move you make Astma och allergier tillhör våra vanligaste folksjukdomar och de har ökat under de senaste fyra decennierna, särskilt bland barn och ungdomar. Under samma period så har inställningen till fysisk aktivitet och olika livsstilsfaktorer i samhället förändrats. Det är allmänt accepterat att fysisk aktivitet är bra for hälsan och viAsthma and allergies are common diseases in adolescents and have increased during the last few decades. All elite level sports activities result in increased risk of asthma and rhinitis regardless of sport practised. Physical activity is at the same time regarded as a health-promoting factor and is recommended both for the prevention and treatment of diseases. The aim of this study was to explore

Popular Abstract in Swedish MHC upptäcktes för 60 år sedan då George Snell konstaterade att möss som var genetiskt lika inte stötte bort transplanterad hud medan genetiskt olika möss gjorde det. Men det var inte förrän långt senare som man insåg vilken roll som MHC spelar i immunförsvaret hos alla vertebrater. Sedan ett par decennier tillbaka är detta ett välstuderat område speciellt hos människanIn birds the major histocompatibility complex (MHC) organization differs both among and within orders. Galliformes often have simple arrangements with few transcribed MHC genes whilst many songbirds (Passeriformes) have a complex arrangement with many MHC genes and also presence of pseudo-genes. In this thesis I have partly characterized MHC class I in house sparrows (Passer domesticus), sequencin

Popular Abstract in Swedish Njurarna spelar en central roll i de förändringsprocesser som anpassar kvinnans kropp till en graviditet. Många av de förändringar som sker mot slutet av en normal graviditet, påminner om de förändringar man ser vid preeklampsi, havandeskapsförgiftning, om än mindre uttalade. Preeklampsi är ett allvarligt risktillstånd som kan uppkomma under graviditet och en av de störThe kidneys play a pivotal role in the adaptive physiology of the pregnant woman, presenting some changes at term similar to the changes found in preeclampsia – a state of increased risk of fetal and maternal morbidity and mortality. The aim of these investigations was to explore possible similarities in blood pressure regulation, renal function and structure in normal term and preeclamptic pregna

Background and purpose: Pain is highly prevalent in Parkinson's disease (PD), impacting patients’ ability, mood and quality of life. Detecting the presence of pain in its multiple modalities is necessary for adequate personalized management of PD. A 14-item, PD-specific, patient-based questionnaire (the King's Parkinson's Disease Pain Questionnaire, KPPQ) was designed corresponding to the rater-ba

Very few absolute palaeointensity data exist from Holocene-aged rocks in New Zealand. Here we present a new suite of high-quality palaeointensities, supported by detailed rock magnetic investigations. Samples from 23 sites representing 10 distinct eruptive units of the Tongariro Volcanic Centre, Taupo Volcanic Zone, New Zealand, were studied. Both traditional double heating and microwave palaeoint

Purpose: Obstructive sleep apnea (OSA) is a common disease in patients with coronary artery disease (CAD). Approximately 40–80% of cardiovascular disease patients have obstructive sleep apnea. The manifestation of it can vary significantly in different types of CAD patients. This systematic review and meta-analysis investigate the prevalence and severity of OSA in patients with acute coronary synd

In recent years, it has become increasingly clear that promiscuity plays a key role in the evolution of new enzyme function. This finding has helped to elucidate fundamental aspects of molecular evolution. While there has been extensive experimental work on enzyme promiscuity, computational modeling of the chemical details of such promiscuity has traditionally fallen behind the advances in experim

Yellow rust (Puccinia striiformis f. sp. Tritici) is a crop disease caused by a fungus that regularly infects wheat and causes yield loss in Ethiopia. The disease has a significant impact on the country’s crop production, food security, health, and socioeconomic well-being. Anticipating yellow rust epidemics can help to better manage them and mitigate their adverse impacts. This study explores t

Syftet med avhandlingen var att undersöka och utvärdera bindningen av molekyler mot ett målprotein som är involverad i tillväxten av cancerceller. Undersökning genomfördes på Red Glead Discovery med WAC (weak affinity chromotography) som är en kromatografisk separationsmetod, där molekyler med olika vikt pumpas genom olika kolonner och retentionstiden för molekylerna i kolonnen detekteras. MolekylThe drug discovery and development process has changed dramatically during the last decades and the growth of more efficient techniques as high throughput screening combined with combinatorial synthesis using amino acids and carboxylic acids on solid support makes it possible to investigate the affinity of molecules towards a biological target. Fragment based drug discovery (FBDD) has been impleme

Deposition of ferroelectric hafnium zirconium oxide (HZO) on semiconductor samples with Atomic Layer Deposition (ALD) has proven to be a viable method of production. But while the physical processes of ALD deposition is relatively well know, there exists some gaps in knowledge about different parameters for the ALD and the resulting depositions. This work is about analysing mainly how the purge ti

To continue the development of novel therapeutics to treat bladder cancer, a reliable model for preclinical testing of treatments and studying of the disease mechanism is essential. Ex vivo culturing of precision cut tumor slices (PCTS) provides a model that can retain the tumor architecture and its tumor microenvironment including the immune cell compartment, but data on PCTS based on bladder tum

Förslag på studieplanering för blivande präster - Start VT2023 Huvudspecialisering inkl kandidatuppsats i Religionshistoria Svenska kyrkans akademiska studiekrav: 255 hp inkl teol kand och magisterexamen 2011 års studieordning, CTR 2013 års utbildningsordning för blivande präster, Svenska kyrkan 180 hp Teol kand Religionsvetenskap och teologi: Grundkurs 30 Specialisering inkl examensarbete - RH 60

https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/studiegang/Planering_blivande_praester_RHI_VT23.pdf - 2026-05-25

Förslag på studieplanering för blivande präster - Start VT2023 Huvudspecialisering inkl kandidatuppsats i Kyrko- och missionsstudier Svenska kyrkans akademiska studiekrav: 2011 års studieordning, CTR 255 hp inkl teol kand och magisterexamen 2013 års utbildningsordning för blivande präster, Svenska kyrkan 180 hp Teol kand Religionsvetenskap och teologi: Grundkurs 30 Specialisering inkl examensarbet

https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/studvag/Planering_blivande_praester_KMS_VT23.pdf - 2026-05-25

Förslag på studieplanering för blivande präster - Start VT2024 Huvudspecialisering inkl kandidatuppsats i Kyrko- och missionsstudier Svenska kyrkans akademiska studiekrav: 2011 års studieordning, CTR 255 hp inkl teol kand och magisterexamen 2013 års utbildningsordning för blivande präster, Svenska kyrkan 180 hp Teol kand Religionsvetenskap: Grundkurs 30 Specialisering inkl examensarbete - KMS 45 V

https://www.ctr.lu.se/fileadmin/user_upload/ctr/pdf/studvag/Praestplaneringar/Start_VT24/Planering_blivande_praester_KMS_VT24.pdf - 2026-05-25