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Bacterial extracellular vesicles (EVs) are shed during growth by the respiratory pathogens Pseudomonas aeruginosa and Haemophilus influenzae. Vesicles trigger release of antimicrobial compounds and proteins of the complement, which are partly regulated by vitronectin. We hypothesized that vitronectin is elevated in the lungs during pneumonia, that respiratory epithelial cells produce vitronectin u

Fast kicker systems are required for the proposed upgrade of ALS to a diffraction-limited light source (ALS-U). The main approach is to have multiple stripline kicker magnets driven by inductive adders. The design details of the kicker structures and the inductive adder options will be discussed.

Background & Aims: Glucagon-like peptide-2 (GLP-2) is a 33-amino acid peptide hormone secreted by enteroendocrine cells in response to nutrient ingestion. GLP-2 stimulates crypt cell proliferation leading to expansion of the mucosal epithelium; however, the mechanisms transducing the trophic effects of GLP-2 are incompletely understood. Methods: We examined the gene expression profiles and gro

Objective: To evaluate the safety, adherence, and efficacy of self-administered balance and resistance exercise using the Borg scale in patients with chronic kidney disease, and to examine relationships between exercise intensity or duration and baseline measures, and relationships between change in physical performance and baseline measures, intensity, or duration. Design: Post-hoc analysis of a

Målgruppen för vår forskning är vuxna med begränsningar i delaktighet och vardagsliv på grund av sjukdom, skada eller ålder. Forskningen baseras på teorier och modeller hämtade bland annat ur arbetsterapi och aktivitetsvetenskap, gerontologi, rehabilitering, hälsoekonomi, utvärdering och implementeringsforskning. Forskargruppen är knuten till Centre for Ageing and Supportive Environments, CAThe target group of our research is adults with limitations in participation and everyday life due to illness, injury or age. Our research is based on theories and models derived mainly within occupational therapy and occupational science, gerontology, rehabilitation, health economics, evaluation and implementation research. The research group is linked to the Centre for Ageing and Supportive

This thesis delves into Louis Spohr and his First Concerto for Clarinet and Orchestra, Op. 26, starting with an overview of the composer's life and his work. The analysis will provide a better understanding of the meaning and characteristics of this composer's writing during his musical career. The thesis also explores the performance of his concerto that is closer to the composer’s origin

Thymus colonisation and thymocyte positioning are regulated by interactions between CCR7 and CCR9, and their respective ligands, CCL19/CCL21 and CCL25. The ligands of CCR7 and CCR9 also interact with the atypical receptor CCRL1 (also known as ACKR4), which is expressed in the thymus and has recently been reported to play an important role in normal alpha beta T-cell development. Here, we show that

The aim of the study has been to investigate how discriminatory factors interlink and are conceptualized in governmental policies and strategies, within the field of gender equality and anti-racism work in Sweden. The Study used WPR approach developed by Bacchi as the method of policy analysis, a theoretical lens of intersectionality has been used to understand who the documents are representing i

This paper critically investigates the impact and meaning of managerialism in a pharmaceutical firm by exploring its shaky basis. Managers' explanations of the failure in research leading to new products showed considerable variety. This reflects the absence of any shared understanding of research inefficiencies and difficulties to determine the roots of the problems. Despite this people blame bad

The government of Finland has the ambition of making Finland the first fossil-free welfare state in the world and reaching carbon neutrality in 2035. Simultaneously, worktime reduction and basic income have been matters of vivid political debate. Both worktime reduction and basic income are go-to solutions for post-growth scholars as ways to arrange welfare in a non-growing economy. These initiati

The International Society for Clinical Densitometry (ISCD) has published position statements on topics relating to the use and interpretation of measurements of bone mineral density (BMD). The most recent appeared in the Journal of Clinical Densitometry (1) and was republished in the Journal of Endocrinology and Metabolism and in Osteoporosis International (2,3). The topics included the indication