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Genomiska analyser av urinblåscancer

Uroteliala cancer, cancer i urinblåsan, är indelad i två större typer, icke-muskelinvasiv och muskel-invasiv cancer, med skilda biologiska och kliniska egenskaper. Prognos och behandling är i huvudsak baserade på patologiska kriterier. Det faktum att endast 20-25% av höggradiga tumörer med lågt tumörstadium bekräftas efter patologisk eftergranskning, och att 30% av patienterna med intermediärt tumUrothelial cancer, bladder cancer, is divided in two major subtypes, non-muscle invasive and muscle-invasive, with very distinct biological and clinical properties. Prognosis and treatment are mainly based on pathological criteria. The fact that only 20-25% of high grade low stage tumors are confirmed by review pathology, and that 30% of patients with intermediate stage tumors are upstaged after r

Grupp för neurometabola och neurogenetiska sjukdomar

I vår forskning fokuserar vi på sällsynta metabola och andra genetiska sjukdomar som påverkar centrala nervsystemet. Vi strävar efter att förbättra vården för patienter genom att fokusera våra forskningsprojekt på de kliniska aspekterna av dessa sällsynta sjukdomar.In our research we focus on rare metabolic and other genetic disorders that impact the central nervous system. We aim to improve the care for patients by focusing our research projects on the clinical aspects of these rare disorders.

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Since the early 1980’s and up until today many organizations have realized the importance of paying more and more attention to the effective strategic planning of the information systems resources. There are several reasons for this that where recognized by Pyburn (1983), one was the high speed of technological progress both in regards to IT and Telecoms facilities. Another key factor, which is ve

Avdelningen för bioteknik och teknisk mikrobiologi

Avdelningen för bioteknik och teknisk mikrobiologi bedriver forskning och utbildning på grund- och forskarnivå inom olika områden av bioteknik såsom industriell bioteknik för kemikalier, bioenergi och livsmedel, miljöbioteknik, och bioteknik för hälsa. Teknisk mikrobiologi har omfattande erfarenhet av forskning inom mikrobiell fysiologi och bioanalys. Målet är att förstå, konstruera och kontrollDivision of Biotechnology and Applied Microbiology conducts research and education at undergraduate and postgraduate level within different areas of biotechnology such as industrial biotechnology for biobased chemicals, bioenergy and food, environmental biotechnology, and biotechnology for health. Technical microbiology has extensive experience in research on microbial physiology and bioanalysis.

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Authors of a recent paper demonstrate that, like ERMES (ER-mitochondria encounter structure) in fungal cells, PDZD8 (PDZ domain containing 8) tethers mitochondria to the ER in mammalian cells. However, identifying PDZD8 as a "functional ortholog" of yeast Mmm1 (maintenance of mitochondrial morphology protein 1) is at odds with the phylogenetic data. PDZD8 and Mmm1 are paralogs, not orthologs, whic

Avdelningen för hematologi och klinisk immunologi

Vi studerar blod- och immunsystemet och dess sjukdomar. Ett särskilt fokusområde är hur medfödd genetisk variation påverkar hur blod- och immunceller, och hur sådan variation kan utnyttjas kliniskt. Vilka gener och genmutationer styr t ex risken för blodcancer? Kan vi utnyttja dem för att förebygga och behandla? Vilka styr vår blodgruppsuppsättning? Kan vi utnyttja dem för säkrare transfusion? EttWe study the blood and immune system and its diseases. A particular focus area is how congenital genetic variation affects blood and immune cells, and how such variation can be utilized clinically. Which genes and gene mutations control, for example, the risk of blood cancer? Can we use them to prevent and treat? Who controls our blood group set? Can we use them for safer transfusion? Another impo

Institutionen för arkeologi och antikens historia

Institutionen för arkeologi och antikens historia bedriver forskning och utbildning inom fyra ämnen – antikens kultur och samhällsliv, arkeologi, historisk arkeologi och historisk osteologi. Institutionen har funnits i olika former vid Lunds universitet sedan 1805 men fick sin nuvarande sammansättning 2001. Sedan 2016 rymmer institutionen även Laboratoriet för digital arkeologi (DARKLab), en infraThe Department of Archaeology and Ancient History conducts research and education in four subjects – Classical Archaeology and Ancient History, Archaeology, Historical Archaeology and Historical Osteology. The department has existed in various forms at Lund University since 1805 but was given its current composition in 2001. Since 2016, the department also houses the Laboratory for Digital Archaeo

Lund OsteoArthritis Division - Nedbrytning av ledbrosk: en biologisk process som leder till artros

Artros, vår vanligaste ledsjukdom, orsakar smärta och funktionsnedsättning och drabbar främst knä, höft och fingerleder. Dagens behandling är fokuserad på smärtlindring, sjukgymnastik och eventuell ledersättning. Vid ledskada och artros bryts broskproteiner ner, och ledskador är en riskfaktor för artros, men mekanismerna som leder fram till artros är till stor del okända. Vi studerar de molekyläraOsteoarthritis (OA), the most common joint disease, causes pain and disability and mainly affects the knee, hip and finger joints. Treatment focuses on pain relief, physical therapy and eventually prosthesis. Cartilage proteins are degraded after joint injuries and in OA; joint trauma is a risk factor for OA, but the mechanisms leading to OA are mainly unknown. We study the molecular and structura

Studieadministrativa system

Avdelningen Studieadministrativa system ansvarar bland annat för systemen Ladok, Lubas och SUNET Survey. Avdelningen arbetar med systemförvaltning samt systemadministration och ger utbildning och service till användarna.Study Administration Systems have responsibility for the Ladok, Lubas and SUNET Survey systems, among others. The unit works on system management and system administration and provides training and service to users. More information for staff: https://www.staff.lu.se/study-administration-systems

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Research Question: How do Swedish coworking firms internationalise, and what are the Key Success Factors allowing for a successful internationalisation? Purpose: This study investigates what drives international expansion for Swedish coworking firms. It also sees why these internationalisation projects were or were not successful. By identifying the key factors behind the projects, the study aims

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This study aims to investigate consumers’ perceptions of luxury fashion brands and whether these perceptions differ with and without the context of luxury rental platforms. A qualitative methodology was adapted, using semi-structured interviews and an abductive research approach. In order to investigate consumer perception of luxury brands in the context of rental platforms, the study applied con

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Purpose To examine if Chinese acquirers create short-term shareholder wealth through cross-border acquisitions, measured by fluctuations of the stock price of the acquiring firm. Additionally, to investigate if industrial, institutional and cultural independent variables affect the cumulative abnormal returns. Methodology The study is quantitative with a deductive approach and based on the tradit

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Today, as our cities are becoming increasingly dense - the role of internal spaces are rising as ever-more important in defining urbanity. And in a moment in which our private lives have become exposed and controlled in almost every aspect, the interior has become the eminent space of refuge, providing anonymity and freedom. In Is the New Out offers a radical reexamination of the interior as the l