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Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat
Background: MRI is an important tool in the prostate cancer work-up, with special emphasis on the ADC sequence. This study aimed to investigate the correlation between ADC and ADC ratio compared to tumor aggressiveness determined by a histopathological examination after radical prostatectomy.Methods: Ninety-eight patients with prostate cancer underwent MRI at five different hospitals prior to radi
Background: Hypertension is the leading modifiable risk factor for cerebral small vessel diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially affect microvascular function in SVDs. Aims: To test whether amlodipine has a beneficial effect on microvascular function when compared to either losartan or atenolol, and whether losartan has a beneficial effect when comp
Iron-centered N-heterocyclic carbene compounds have attracted much attention in recent years due to their long-lived excited states with charge transfer (CT) character. Understanding the orbital interactions between the metal and ligand orbitals is of great importance for the rational tuning of the transition metal compound properties, e.g., for future photovoltaic and photocatalytic applications.
A search is presented for the pair production of higgsinos χ˜ in gauge-mediated supersymmetry models, where the lightest neutralinos χ˜1 0 decay into a light gravitino G˜ in association with either a Higgs h or a Z boson. The search is performed with the ATLAS detector at the Large Hadron Collider using 139 fb−1 of proton–proton collisions at a centre-of-mass energy of s=13
A search is presented for non-resonant Higgs boson pair production, targeting the bbZZ, 4V (V = W or Z), VVττ, 4τ, γγVV and γγττ decay channels. Events are categorised based on the multiplicity of light charged leptons (electrons or muons), hadronically decaying tau leptons, and photons. The search is based on a data sample of proton-proton collisions at s = 13 TeV recorded with the ATLAS detector
Half of parents to infants and toddlers experience unwanted intrusive thoughts (UITs) about intentionally harming their child. For some, this can lead to impaired parental self-efficacy, elevated parental stress, and symptoms of depression. Many do not disclose their thoughts due to shame. Our research group has developed a self-guided online cognitive intervention for parents with distressing UIT
Background and aim: Although recommended, the P-score used for assessing the pertinence / relevance of findings seen in small bowel (SB) capsule endoscopy (CE) is based on a low level of knowledge. The aim of this study was to evaluate the clinical relevance of the most frequent SBCE findings through an illustrated script questionnaire. Materials and Methods: Sixteen types of SBCE findings were il
In the last ten years, x-ray free-electron lasers (XFELs) have been successfully employed to characterize metalloproteins at room temperature using various techniques including x-ray diffraction, scattering, and spectroscopy. The approach has been to outrun the radiation damage by using femtosecond (fs) x-ray pulses. An example of an important and damage sensitive active metal center is the Mn4CaO
Multiconfiguration Dirac-Hartree-Fock (MCDHF) calculations and relativistic configuration interaction (RCI) calculations are performed for states of the 3s23p2, 3s3p3 and 3s23p3d configurations in the Si-like ions Ti IX - Ge XIX, Sr XXV, Zr XXVII and Mo XXIX. Valence and core-valence electron correlation effects are accounted for through large configuration state function expansions. Calculated en
A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb-1 of proton-proton collisions at s=13 TeV collected with the ATLAS detector at the LHC during 2015-2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distr
This paper reports on a search for electroweak diboson (WW/WZ/ZZ) production in association with a high-mass dijet system, using data from proton-proton collisions at a center-of-mass energy of s=13 TeV. The data, corresponding to an integrated luminosity of 35.5 fb-1, were recorded with the ATLAS detector in 2015 and 2016 at the Large Hadron Collider. The search is performed in final states in wh
Immunotherapies with antibody-drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceome and how it is modulated by the tumor microenvironment. Here, we decode the surfaceome and endocytome and its remodeling by hypoxic stress in glioblastoma (GBM
Key performance indexes (KPIs) in various forms have always been used in one way or another in the production and processing of raw materials. The need for KPIs was accentuated with the advent of industrialism in the western world. The way and strategy of manufacturing industrial products has been divided into several so-called developmental transformations. Primarily after the depression of the 1
A generic search for resonances is performed with events containing a Z boson with transverse momentum greater than 100 GeV, decaying into e + e − or μ + μ −. The analysed data collected with the ATLAS detector in proton-proton collisions at a centre-of-mass energy of 13 TeV at the Large Hadron Collider correspond to an integrated luminosity of 139 fb −1. Two invariant mass distributions are exa
A search for pair production of scalar leptoquarks, each decaying into either an electron or a muon and a top quark, is presented. This is the first leptoquark search using ATLAS data to investigate top-philic cross-generational couplings that could provide explanations for recently observed anomalies in B meson decays. This analysis targets high leptoquark masses which cause the decay products of
Extensive COVID-19 information can generate information overload and confusion. Denmark and Sweden adopted different COVID-19 management strategies. Aim This study aimed to compare search strategies, perceptions and effects of COVID-19 information, in general and specifically in social media, in residents in Denmark and Sweden. Subject and methods Quantitative data from a sample of respondents (n AimExtensive COVID-19 information can generate information overload and confusion. Denmark and Sweden adopted different COVID-19 management strategies.This study aimed to compare search strategies, perceptions and effects of COVID-19 information, in general and specifically in social media, in residents in Denmark and Sweden.Subject and methodsQuantitative data from a sample of respondents (n = 61
The results of a search for direct pair production of top squarks and for dark matter in events with two opposite-charge leptons (electrons or muons), jets and missing transverse momentum are reported, using 139 fb−1 of integrated luminosity from proton-proton collisions at s = 13 TeV, collected by the ATLAS detector at the Large Hadron Collider during Run 2 (2015–2018). This search considers the
Bakgrund Teknikutvecklingen inom hälso- och sjukvårdsområdet möjliggör ständigt nya och mer avancerade sätt att distansmonitorera och vårda patienter digitalt. Digitaliseringen inom hälso- och sjukvårdsområdet i form av till exempel hälsoapplikationer gör det möjligt för patienter och personal att ha kontakt och kommunicera digitalt med varandra (WHO, 2011). itACiH är ett digitalt system där patie
