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Aim: The study was designed to document the incidence of non-immune hydrops fetalis (NIHF) at birth and characterise associated outcomes and obstetric complications. Methods: Data on more than 1.9 million births were extracted from the Swedish Birth Register for 1997-2015. Pregnancies not affected by NIHF served as controls. National registers on mortality and hospitalisations provided follow-up i
Background: Positive psychology indicators like well-being and life satisfaction may play a pivotal role in pain-related outcomes. In this study, we aimed to examine the prospective associations of positive well-being and life satisfaction with pain severity. Methods and Subjects: This longitudinal study, with a follow-up of 2 years, included 9361 participants (4266 males, 5095 females; mean age:
Serum levels of Anti-Mullerian Hormone (AMH) have been shown to be biomarker for prediction of the quantitative aspects of ovarian reserve. On the male side, sperm chromatin structure assay (SCSA) DNA fragmentation index (DFI) has been demonstrated to be an important predictor of outcomes in standard IVF procedures but to less degree in intracytoplasmic sperm injection procedures (ICSI). The purpo
Purpose: Differences exist concerning when and how to perform lymph node dissection (LND) during radical prostatectomy due to lack of high-grade evidence to its safety and efficacy. We aimed to compare readmission rates between limited and extended LND during open radical prostatectomy (ORP) and robot-assisted radical prostatectomy (RARP). Materials and methods: We conducted a prospective trial of
PURPOSETo assess interval cancer rate in a large, prospective digital breast tomosynthesis (DBT) screening trial in comparison with a concurrent screening population and to assess tumor characteristics of interval cancers in DBT-screening.METHOD AND MATERIALSThe prospective ****Trial, comparing digital breast tomosynthesis (DBT) with digital mammography (DM) in 14,848 women has shown a significant
Background: Molecular signatures in prostate cancer (PCa) tissue can provide useful prognostic information to improve the understanding of a patient's risk of harbouring aggressive disease. Objective: To develop and validate a gene signature that adds independent prognostic information to clinical parameters for better treatment decisions and patient management. Design, setting, and participants:
BACKGROUND: Electronic health records (EHRs) are generated at an ever-increasing rate. EHR trajectories, the temporal aspect of health records, facilitate predicting patients' future health-related risks. It enables healthcare systems to increase the quality of care through early identification and primary prevention. Deep learning techniques have shown great capacity for analyzing complex data an
I denna studie har elva svenska idrottare som dopat sig intervjuats – tio styrkelyftare och en tyngdlyftare. Idrottarna har varit verksamma på tävlings- till elitnivå, och har fällts för minst en dopingförseelse 1990 till och med 2006. Syftet med studien har varit att identifiera och analysera sociala processer som ligger bakom bruket. Anabola Androgena Steroider (AAS) var det preparat som samtlig
Standardized Cancer Patient Pathways (CPPs) were introduced in Swedish healthcare starting in 2015 to improve diagnostics for patients with symptoms of cancer, patient satisfaction and equity of care between healthcare providers. An inclusion target and a time target were set. Our primary aim was to visualize the patient population going through CPPs, in terms of investigation time and indications
OBJECTIVE: To summarize the effectiveness of management strategies and rehabilitation approaches for knee joint structural and molecular biomarker outcomes following anterior cruciate ligament (ACL) and/or meniscal tear. DESIGN: Intervention systematic review. LITERATURE SEARCH: We searched the MEDLINE, Embase, CINAHL, CENTRAL, and SPORTDiscus databases from their inception up to November 3, 2021.
Extra charges in semiconductor nanocrystals are of paramount importance for their electrically driven optoelectronic and photovoltaic applications. Optical excitations of such charged nanocrystals lead to rapid recombinationviaan Auger process, which can deteriorate the performance of the corresponding devices. While numerous articles report trion Auger processes in negatively charged nanocrystals
Purpose: In addition to incisional hernia, inguinal hernia is a recognized complication to radical retropubic prostatectomy. To compare the risk of developing inguinal and incisional hernias after open radical prostatectomy compared to robot-assisted laparoscopic prostatectomy. Method: Patients planned for prostatectomy were enrolled in the prospective, controlled LAPPRO trial between September 20
Background: Lower urinary tract symptoms due to benign prostate enlargement (LUTS/BPE) can lead to significant disturbances to health-related quality of life (HRQoL) and psychological well-being. The aim of this study was to evaluate the effect of pharmacological treatment of LUTS/BPE on disease specific and generic QOL measures. Methods: Evolution was a European prospective, multicenter multi-nat
Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is
Arbetstagarskyddet vid verksamhetsöverlåtelser regleras inom Europeiska unionen (EU) av Rådets direktiv 2001/23/EG av den 12 mars 2001 om till-närmning av medlemsstaternas lagstiftning om skydd för arbetstagares rättig-heter vid överlåtelse av företag, verksamheter eller delar av företag eller verk-samheter (överlåtelsedirektivet). I svensk rätt har reglerna implementerats ge-nom ändringar i lag (The protection of employees in the case of business transfers is regulated within the European Union (EU) by Council Directive 2001/23/EC of 12 March 2001 on the approximation of the laws of the Member States relating to the safeguarding of employees’ rights in the event of the transfer of under-takings, businesses or parts of undertakings or businesses (Transfer of Un-dertakings directive). In Sw
Technical assistance to public sector organisations is a much-debated topic and showcases a considerable size in contemporary international development assistance. Yet, the empirical evidence base on which factors contribute to the outcomes of projects within this field is surprisingly slim and diffuse. Particularly, the mechanisms through which different factors affect project outcomes remains un
Sweden is a state governed by the rule of law, and is based on many different principles in order to ensure a functioning justice system. An important prin-ciple is that the rulings from the courts should be adamant, also known as the principle of firmness. The ruling of the court shall stand when it has gained legal force and this is also known as the negative legal force of a judgment. The human
