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Aim: To compare two different regimens for children diagnosed with type 1 diabetes: hospital-based care or hospital-based home care (HBHC), referring to specialist care in a home-based setting. Method: The trial took place in Sweden with a randomized controlled design and included 60 children, aged 3-15 years. After 2-3 days with hospital-based care, children were randomized to either continue
In this paper we demonstrate the presence of two novel in vivo autophosphorylation sites in the c-Kit/stem cell factor receptor (c-Kit/SCFR): Tyr-703 in the kinase insert and Tyr-936 in the C-terminal tail. We furthermore demonstrate that the adapter protein Grb2 is a specific binding partner for both phosphorylated Tyr-703 and phosphorylated Tyr-936, whereas the adapter protein Grb7 binds selecti
Popular Abstract in Swedish Ultraljudundersökning av hjärtat (ekokardiografi) har under det senaste decenniet fått en alltmer framträdande roll i diagnostiken av hjärtsjukdomar och används ofta för att vägleda medicinska beslut inom hjärtsjukvården. Ekokardiografi är av central betydelse framförallt vid undersökning av vänsterkammarens pumpförmåga (systoliska funktion) och hjärtklaffarnas funktionTwo specific areas of development in echocardiography are assessment of left ventricular (LV) diastolic function and myocardial ischemia. This thesis describes echocardiographic methodology in these two areas. In the first study, two new echocardiographic methods, the early diastolic flow propagation velocity (Vp) and the early diastolic atrioventricular plane downward slope (EDS), were tested as
Regional cerebral blood flow was measured in 35 patients with organic dementia (Alzheimer's disease, n = 13, vascular dementia, n = 17, frontotemporal dementia, n = 5) and orthostatic hypotension. Measurements were performed during supine rest and during head-up tilt (60 degrees). Despite marked blood pressure falls, few patients had symptoms of orthostatic hypotension. All three dementia groups h
The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec
Abstract: Administrative regions do not necessarily correspond to areas that are homogenous in terms of innovation intensity. Although this has been recognized in the literature, quantitative evidence that explicitly considers this problem is rare. Using spatial exploratory analysis on detailed regional data derived from a census of R&D performers in the Czech Republic, we identify local spati
Wireless wearable medical devices located on the opposite side of the body communicate through creeping waves. The creeping waves undergo exponential attenuation with distance. Hence, an analytical propagation model is useful to estimate the link loss for a reliable link. In this document, we have presented analytical link loss models for the wireless propagation channel between the devices locate
Water for Injection (WFI) is a critical utility in pharmaceutical manufacturing, traditionally produced through an energy-intensive distillation process. This thesis investigates the feasibility of a more sustainable alternative, ambient WFI production using membrane-based purification technologies combined with ozonation in the storage and distribution loop. Conducted in collaboration with AstraZ
The European Union’s sustainability reporting framework, which includes the CSRD and the CSDDD, is widely regarded as a logical progression toward achieving the 2050 climate goals. The EU has faced criticism regarding the sustainability reporting directives, primarily due to concerns over the EU’s global competitiveness and the readiness of undertakings to comply. Consequently, there have been inc
The purpose of this essay is to assist teachers of Swedish who are considering using the exemption clause while grading. It does this by describing and charting teachers' perceptions of the exemption clause and its purpose in relation to dyslexia. In-service teachers, who feel uncertain about using the exemption clause, may read how other teachers perceive it, and tailor their own usage accord
This study investigated the changes in the physical activity of Japanese breast cancer survivors during and after the state of emergency declaration (SOED) due to the spread of COVID-19. Participants were survivors of stage I-IIa breast cancer diagnosed between the ages of 18 and 60 years who wore a wearable device (Fitbit Versa) before and after the SOED period. Outcomes included steps per day on
The Light Dark Matter eXperiment (LDMX) is proposed to employ a thin tungsten target and a multi-GeV electron beam to carry out a missing momentum search for the production of dark matter candidate particles. We study the sensitivity for a complementary missing-energy-based search using the LDMX Electromagnetic Calorimeter as an active target with a focus on early running. In this context, we cons
In this article I shed light on the phenomenon of Chinese young people’s conversion to Christianity and argue that it is often closely tied to a utopian longing for what is missing in their lives (Bloch 1907). Through a person-centered account of two young people, I explore their quests to escape the temporal predicament of endless striving 'fuzao' and search for a better life based autotelic valu
Purpose: The puspose with our essay is to investigate how an acquisition can affect leadership. We want to specialize us by analysing how a leadership and the employees in a smaller company can be affected by an acquisition by a larger organization. We also want to investigate how a good leadership should be in a small company due to an acquisition. Methodology: This essay is based on a qualitativ
