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The aggregation of proteins into amyloid fibrils via erroneous folding, also known as misfolding, occurs in several diseases. As a consequence, the study of the kinetics and thermodynamics of this process is currently intensely pursued. Here, we study a minimalistic lattice-based model for amyloid formation using Monte Carlo techniques to sample the grand canonical ensemble, where the chemical pot
The relationship between business cycles and mortality has been a highly debated subject in the field of economics. The majority of previous studies, using the unemployment rate as the main proxy for macroeconomic conditions, have found ambiguous effects largely depending on how the effect is estimated. This thesis follows the methodology used by Ruhm (2000), but instead applies aggregate data for
Titel- Sex and the city för män? ?En kvalitativ studie om manligheter i förändring Författare- Malvina Britts Avdelning- Avdelningen för Medie- och kommunikationsvetenskap Problem: Området som min studie rör sig inom är representationen av maskulinitet. Förändringar i representationen av maskulinitet diskuteras i olika sammanhang och en specifik drama/komediserie, Entourage, har på sistone utmä
Abstract This thesis examines whether it is possible to ascertain a measurable difference between granted and refused grant applications with automatic methods. A corpus of project descriptions from the Swedish Science Council was examined with different classification techniques and using different linguistic features. A Naive Bayes classifier is shown to be a good predictor for this type of pro
The aim of this thesis is to investigate why the municipality of Lund has not done more, in relation to LundaMaTs, to inform and promote the purchasing of organic provisions to the public. This is of interest since it is determined in the Rio Declaration and Agenda 21 that the current unsustainable production and consumption patterns need to change. The local authorities play an important role
Presentation of problem: The movement of sediment parallel to the coast by waves and currents is known as longshore sediment transport or littoral transport. Throughout the years, researchers have found that knowledge of longshore sediment transport is important in connection with coastal engineering design, such as construction of breakwaters at harbour entrances, dredging of navigation channels,
The present study investigated the effects of three factors on the level of realism in frequency judgements. These factors were: Instruction (No correction for guessing/Correction for guessing), Format (whether the frequency judgements were made in terms of absolute numbers or in percent) and Difficulty level (easy/hard set of questions). All three factors were found to have a significant effect o
The present research is aimed at analyzing spirituality according to the way it is presented in academic management literature. To uncover comprehensively way this phenomenon is described, a thorough scientific analysis of the selected articles was performed including coding the materials, systematically categorizing them as well as critically investigating particular aspects. While conducting the
Sub-Saharan Africa suffers from a severe infrastructure deficit, particularly in the power sector and this is broadly recognised as a barrier to poverty alleviation, economic growth and sustainable development in the region. At the same time, the region is rich in natural resources and the mining sector, which already makes a significant contribution to national economies is currently expanding an
This thesis investigates the nonlinear detector response to Laser Induced Phosphorescence signal originating from the CdWO4 phosphor. A matrix method is utilized to map the detectors linearity for decay-time determination as function of detector gain and number of photons reaching the detector. The Matrix is created by scanning the energy of the laser beam hitting the phosphor thus changing the ph
Humans have always communicated with each other. When the smartphone technology was launched on the market, it revolutionized the way people communicate. This smartphone technology is constantly evolving and during 2014 wearable computing seems to be in the focal point at most smartphone technology conferences. This master thesis aims to discover how a wearable computing device can further develo
The many-body problem in quantum mechanics always presents new challenges and ways to discover new properties of existing materials. The difficulty (if not the impossibility) to solve the many-body problem analytically makes the numerical methods an appealing approach. Here we consider a Python code, which is under development to become an open-source tool to perform studies of finite lattice syst
Inflammation and subsequent endothelial dysfunction are main players in the vascular component of hypertension, and recent findings points to a key role of Sphingosine- 1-Phosphate and its signaling pathways in its pathophysiology. In neurodegenerative disorders such as Alzheimer’s disease, hypertension is the main modifiable risk factor, but insights regarding S1P receptor modulation in response
This Master Thesis aims to show an approach to the design of parallel robots,specifically the development of its kinematics. To do this, screw theory will be used, focusing on its theoretical bases and taking it later to practice. First, a theoretical definition of the inverse and forward kinematics of a parallel robot is carried out. Subsequently, algorithms are generated in Python that verify t
In this thesis, a new probabilistic risk assessment tool for road tunnels has been verified and validated. The verification and validation were performed along with a literature review to find different key variables that affect the risk in a road tunnel and find out how these variables can be handled. Examples of variables are heat release, ventilation mode and factors within evacuation modelling
In the field of computational biology, fluorescence microscopy images often constitute the input source of information. The process of binarization of raw images to delineate interesting objects requires image segmentation into signal and background pixels. Several methods to perform image segmentation exist, the Otsu method being a popular unsupervised example. The Otsu method's lack of pro
Globalization has led to the emergence of global value chains (GVCs) and most of the world’s trade is now in intermediate inputs. This has raised questions about employment in GVCs and attracted the interest of researchers and policymakers alike, but is difficult to study empirically. This paper investigates job creation in simple and complex GVCs for 43 economies between 2000 and 2014 on the basi
