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Induction of the mitochondrial permeability transition (MPT) has been implicated in cellular apoptosis and in ischemia-reperfusion injury. During MPT, a channel in the inner mitochondrial membrane, the mitochondrial megachannel, opens and causes isolated mitochondria to swell. MPT and mitochondrial swelling is inhibited by cyclosporin A (CsA), which may also inhibit apoptosis in some cells. Treatm

This paper describes the extraction of information on lethal events from the Swedish version of Wikipedia. The information searched includes the persons’ cause of death, origin, and profession. We carried out the extraction using a processing pipeline of available tools for Swedish including a part-of-speech tagger, a dependency parser, and manually-written extraction rules. We also extracted stru

A great amount of research effort has been devoted to theproduction of core-shell nanoparticles for applications in variousfields including biomedical imaging, catalysis, and plasmonics.Such attention to core-shell nanoparticles arise from the fact thatthey can exhibit enhanced physical and/or chemical properties.Furthermore, core-shell particles with distinctly new propertiescompared to those of

During the last two decades a slow but steady change of external factors has set-up new conditions affecting the way in how software producing firms create and leverage innovations. Firms now need to look outside of their boundaries and start interacting with the open environment that encompasses them in order to stay innovative and keep a competitive advantage. To facilitate this shift Requiremen

Rapport från ett seminarium sept. 2014 i Manama i Zimbabwe, om diakonens identitet i Lutherska kyrkan i Zimbabwe och i Sverige, två år efter den första vigningen (ordinationen) av diakoner i Evangelical Lutheran Church in Zombabwe.Report from a seminar i Manama in Zimbabwe September 2014: "The Identity of the Deacon in Zimbabwe and Sweden", two years after the first ordination of deacons in the Evangelical Lutheran Church in Zimbabwe (ELCZ).

Programmes driving ELT design are discussed. The nature and evolution of circum-stellar shells and planetary discs are attractive, while the small angular sizes place basic properties, asymmetry and warps, beyond VLT capability. An ELT is neeed to reveal the conversion processes shell - disc - planets, planetary systems, Earth-like planets, habitability and life signatures. Formation and evolution

Czechoslovak productive efficiency of the iron and steel sector fluctuated below the energy efficiency frontier. Until early 1970s, the country's iron sector was one of the least efficient ones in our sample. It was, however, during the decades of 1970s and 1980s that efficiency measures were adopted and the energy efficiency of the Czechoslovak iron and steel sector increased significantly to, de

In 2010, unmet medical care and sexual health counseling needs were assessed among students at a Ugandan University. Unmet medical care need was associated with poor mental health, experience of sexual coercion, and poor self-rated health. Unmet sexual health counseling need was significantly associated with being female, coming from an urban area, low social participation, poor mental health stat

Popular Abstract in Swedish Benskörhet (osteoporos) är ett tillstånd som definieras av låg benmassa och ökar med stigande ålder. Osteoporos är idag en av de stora folksjukdomarna och man räknar med att en tiondel av alla män och en fjärdedel av alla kvinnor i Sverige drabbas. Tillståndet är i sig symptomfritt men ökar risken att råka ut för ett benbrott (fraktur) redan vid lättare fall. Frakturer The aim of this thesis was to evaluate risk factors for bone fragility and fractures in postmenopausal women in a long-term perspective. The study period spanned from the age of 48 to age 82 and is thus unique in its length. The studied sample was homogeneous and consisted of 390 north European women from a population-based cohort. At the start of the study, general health and lifestyle parameters

A flattening filter free x-ray beam mode was added to an Elekta linear accelerator by placing a flat copper plate in the filter carousel and recalibrating the electron steering servo, gun servo and dosimetry system. Machine configurations were saved onto a separate hard disk in order to remain separate from the clinical configuration. Profile measurements with a Schuster BMS diode array show that

This study describes frequencies and associations between eating difficulties, assisted eating and nutritional status in 520 elderly patients in hospital rehabilitation. Eating difficulties were observed during a meal and nutritional status was assessed with Subjective Global Assessment form. Eighty-two percent of patients had one or more eating difficulties, 36% had assisted eating and 46% malnut

Normal ageing in men is associated with a physiological decline in testosterone levels, but adverse environmental or psychosocial factors may also impair testosterone secretion and cause secondary biological changes. In a number of observational or experimental studies in both animals and man, it has been possible to study the influences on gonadal function of stressful life situations. To underst

Transplantation of progenitor cells to the CNS has shown promise in neuronal and glial replacement and as a means of rescuing host neurons from apoptosis. Here we examined the effect of progenitor grafts on neurite extension in the degenerating retina of rd1 ( retinal degeneration 1) mice. Transplantation of retinal progenitor cells induced increased matrix metalloproteinase-2( MMP2) secretion, pa